| Identification |
|---|
| HMDB Protein ID
| CDBP03719 |
| Secondary Accession Numbers
| Not Available |
| Name
| DENN domain-containing protein 5A |
| Description
| Not Available |
| Synonyms
|
- Rab6-interacting protein 1
- Rab6IP1
|
| Gene Name
| DENND5A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| May be involved in Rab6-mediated GTPase signaling |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p15.4 |
| SNPs
| DENND5A |
| Gene Sequence
|
>3864 bp
ATGAGTGGCGGCGGCGGCGGAGGGGGCTCGGCGCCCAGTCGCTTCGCCGACTACTTTGTC
ATCTGCGGACTGGACACGGAGACCGGGCTGGAGCCGGACGAGCTGTCGGCATTATGCCAG
TACATACAGGCTTCTAAAGCCAGGGATGGTGCCAGCCCTTTCATTTCAAGTACGACTGAA
GGAGAAAATTTTGAGCAGACACCATTGAGAAGAACATTCAAATCTAAGGTCCTTGCACGA
TATCCTGAGAACGTAGAATGGAATCCCTTTGACCAAGATGCAGTAGGAATGCTATGTATG
CCGAAAGGGCTGGCATTCAAGACCCAGGCTGATCCCAGGGAGCCCCAATTCCATGCCTTT
ATTATCACAAGGGAGGATGGCTCTCGGACATTTGGGTTTGCCCTCACATTTTATGAAGAG
GTGACTAGCAAGCAGATCTGCAGTGCAATGCAGACCCTCTACCACATGCACAATGCTGAG
TATGATGTCCTACATGCTCCCCCTGCTGATGACAGAGACCAGAGCAGCATGGAGGATGGT
GAAGACACTCCTGTGACCAAACTGCAGCGCTTCAACTCCTATGACATTAGCCGGGACACT
CTCTACGTCTCTAAGTGCATCTGCCTCATCACACCCATGTCTTTCATGAAGGCATGTCGG
AGCGTGCTGGAGCAACTCCACCAGGCAGTCACTTCACCTCAGCCCCCTCCACTGCCCCTT
GAGAGCTACATATACAACGTACTCTACGAGGTGCCGCTCCCACCTCCTGGCCGGTCCTTG
AAGTTTTCTGGGGTCTATGGGCCAATAATCTGCCAGAGACCAAGTACCAATGAGCTTCCC
CTATTTGACTTTCCTGTCAAAGAGGTTTTTGAACTGCTCGGGGTGGAGAATGTGTTTCAG
CTTTTTACTTGTGCCCTTCTGGAGTTTCAAATCCTGCTCTACTCACAGCATTACCAGAGA
CTGATGACTGTGGCGGAGACGATTACAGCTCTCATGTTTCCTTTCCAGTGGCAGCATGTC
TATGTCCCTATTCTCCCAGCTTCTCTCCTGCATTTCTTAGATGCTCCTGTTCCATACCTG
ATGGGTTTGCATTCCAATGGCCTGGATGACCGGTCAAAGCTGGAGCTGCCTCAAGAGGCT
AACCTCTGCTTTGTGGACATTGACAACCACTTCATTGAGTTGCCAGAGGACTTGCCACAG
TTCCCCAACAAATTGGAGTTTGTCCAGGAAGTCTCTGAGATTCTCATGGCATTTGGAATT
CCCCCTGAAGGGAATCTTCATTGCAGTGAGAGTGCCTCCAAGCTGAAGAGGCTGCGGGCC
TCTGAGCTTGTCTCGGACAAGAGGAATGGGAACATTGCTGGCTCCCCTTTGCATTCCTAC
GAGCTTCTTAAGGAGAATGAAACTATTGCCCGGCTGCAAGCCTTGGTCAAGAGAACTGGG
GTGAGCCTGGAAAAGTTGGAAGTGCGTGAAGACCCCAGCAGCAATAAGGATCTCAAAGTT
CAGTGTGATGAAGAAGAACTCAGGATTTACCAGCTAAACATTCAGATCCGGGAAGTTTTT
GCAAATCGTTTCACTCAGATGTTTGCAGATTATGAGGTGTTTGTCATCCAACCCAGCCAG
GATAAGGAATCCTGGTTTACCAACAGGGAGCAAATGCAAAACTTTGATAAAGCATCTTTT
CTGTCAGATCAGCCTGAGCCCTACCTGCCCTTCCTCTCAAGATTCCTGGAGACCCAGATG
TTTGCATCTTTCATTGACAACAAAATAATGTGTCATGATGATGATGATAAAGACCCTGTA
CTCCGGGTATTTGATTCCCGAGTTGACAAGATCAGGCTGTTGAATGTTCGGACACCTACT
CTCCGTACATCCATGTACCAGAAGTGTACCACTGTGGATGAAGCAGAGAAAGCAATTGAG
CTGCGTCTGGCAAAAATTGACCATACTGCAATTCACCCACATTTACTTGACATGAAGATT
GGACAAGGGAAATATGAGCCGGGCTTCTTCCCTAAGCTGCAGTCTGATGTACTTTCCACT
GGGCCAGCCAGCAACAAGTGGACGAAAAGGAATGCCCCTGCCCAGTGGAGGCGGAAAGAT
CGGCAGAAGCAGCACACAGAACACCTGCGTTTAGATAATGACCAGAGGGAGAAGTACATC
CAGGAAGCCAGGACTATGGGCAGCACTATCCGCCAGCCCAAACTGTCCAACCTCTCTCCA
TCAGTGATTGCCCAGACCAATTGGAAGTTTGTAGAGGGCCTGCTGAAGGAATGCCGCAAT
AAGACCAAGAGGATGCTGGTGGAAAAGATGGGCCGAGAAGCTGTGGAGCTAGGGCATGGG
GAGGTGAACATCACAGGGGTGGAAGAGAACACCCTGATTGCCAGCCTTTGTGATCTCCTG
GAAAGGATCTGGAGTCATGGACTACAAGTGAAACAGGGGAAATCAGCCTTATGGTCCCAC
CTGTTACATTATCAGGACAACCGGCAGAGAAAACTCACATCAGGAAGCCTCAGTACCTCA
GGAATACTTCTTGATTCAGAACGTAGGAAGTCTGATGCCAGCTCACTCATGCCTCCCCTG
AGGATCTCCCTGATTCAGGATATGAGGCACATCCAGAACATCGGGGAAATCAAGACTGAT
GTGGGAAAGGCCAGAGCATGGGTGCGACTGTCCATGGAAAAAAAGTTACTTTCCAGACAC
CTGAAGCAGCTCCTCTCAGACCATGAGCTCACCAAAAAGTTATATAAGCGCTATGCCTTC
CTGCGCTGTGATGACGAGAAGGAGCAGTTCCTCTATCACCTCCTGTCTTTCAATGCCGTC
GATTACTTTTGCTTCACCAATGTCTTCACAACTATCCTGATCCCGTACCACATTCTGATC
GTACCAAGCAAGAAGCTGGGGGGCTCCATGTTCACTGCCAACCCATGGATCTGTATATCA
GGAGAATTGGGTGAGACACAGATCATGCAGATTCCCAGGAATGTGCTAGAGATGACCTTC
GAGTGCCAGAACTTGGGGAAGCTTACTACTGTCCAGATTGGCCATGATAACTCTGGGCTG
TATGCCAAATGGCTGGTGGAGTATGTGATGGTCAGGAATGAGATCACAGGACATACCTAC
AAGTTCCCGTGTGGCCGGTGGTTAGGGAAGGGCATGGATGATGGAAGCCTGGAGCGGATC
CTAGTTGGGGAGCTGCTCACATCCCAGCCTGAGGTGGATGAGAGGCCATGCCGGACCCCG
CCGCTGCAGCAGTCCCCCAGTGTCATCCGGAGGCTTGTTACCATCTCACCCAACAACAAG
CCCAAGCTGAACACTGGGCAGATCCAGGAGTCCATCGGGGAGGCAGTCAATGGCATTGTG
AAGCACTTCCATAAGCCTGAGAAAGAGCGAGGCAGTCTGACGCTGTTGCTCTGTGGAGAG
TGTGGCCTTGTCTCGGCCTTGGAACAGGCTTTCCAGCATGGATTTAAATCGCCCCGGCTC
TTCAAAAATGTCTTCATTTGGGATTTCCTGGAAAAAGCACAAACCTATTATGAGACATTA
GAGAAGAATGAAGTAGTCCCTGAGGAAAACTGGCATACAAGAGCCCGGAACTTCTGCCGA
TTTGTCACTGCAATCAACAATACTCCCCGGAACATCGGCAAGGATGGCAAGTTTCAGATG
CTGGTGTGCTTGGGAGCCAGAGATCACCTCCTACACCACTGGATTGCCCTGCTGGCTGAC
TGCCCCATCACTGCACACATGTATGAGGATGTGGCACTGATCAAAGACCATACACTTGTC
AATTCCTTGATTCGTGTGCTGCAGACATTGCAGGAGTTCAACATCACGCTGGAGACGTCC
CTTGTCAAGGGCATCGACATCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1287 |
| Molecular Weight
| 147093.3 |
| Theoretical pI
| 6.68 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>DENN domain-containing protein 5A
MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTE
GENFEQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAF
IITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPPADDRDQSSMEDG
EDTPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPL
ESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQ
LFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYL
MGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGI
PPEGNLHCSESASKLKRLRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTG
VSLEKLEVREDPSSNKDLKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQ
DKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPV
LRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKI
GQGKYEPGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYI
QEARTMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHG
EVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTS
GILLDSERRKSDASSLMPPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRH
LKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILI
VPSKKLGGSMFTANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGL
YAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERPCRTP
PLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGE
CGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEKNEVVPEENWHTRARNFCR
FVTAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLV
NSLIRVLQTLQEFNITLETSLVKGIDI
|
| External Links |
|---|
| GenBank ID Protein
| 44889475 |
| UniProtKB/Swiss-Prot ID
| Q6IQ26 |
| UniProtKB/Swiss-Prot Entry Name
| DEN5A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015213.2 |
| GeneCard ID
| DENND5A |
| GenAtlas ID
| DENND5A |
| HGNC ID
| HGNC:19344 |
| References |
|---|
| General References
| Not Available |