| Identification |
|---|
| HMDB Protein ID
| CDBP03714 |
| Secondary Accession Numbers
| Not Available |
| Name
| Partitioning defective 6 homolog gamma |
| Description
| Not Available |
| Synonyms
|
- PAR-6 gamma
- PAR6D
|
| Gene Name
| PARD6G |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins |
| GO Classification
|
| Function |
| binding |
| protein binding |
|
| Cellular Location
|
- Cell membrane
- Cytoplasm
- Cell junction
- tight junction
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q23 |
| SNPs
| PARD6G |
| Gene Sequence
|
>1131 bp
ATGAACCGAAGTTTTCACAAGTCTCAGACCTTGCGATTCTACGATTGCAGCGCAGTGGAA
GTCAAGAGCAAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCGTCATAAGCCTGGG
AAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTA
ACTATTGGCTATGCAGATGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTC
TGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCAGAAACGAGAGGAG
GCCGAGCGTGGCAGCCTCGGCGCGGGCTCGCTGTGCAGGCGGAGGCGGGCGCTGGGCGCG
CTGCGTGATGAAGGACCCCGGCGGCGTGCACACCTGGACATCGGCCTCCCGCGCGACTTC
CGCCCCGTATCATCCATCATCGATGTGGACCTGGTCCCCGAGACGCACCGGCGAGTGCGG
CTGCACCGGCACGGCTGCGAGAAGCCGCTGGGCTTCTACATCCGCGATGGCGCCAGCGTG
CGCGTGACCCCGCACGGGCTGGAGAAGGTGCCCGGCATCTTCATCTCGCGCATGGTACCC
GGGGGCCTGGCGGAGAGCACCGGGCTGCTGGCTGTGAATGACGAGGTCCTGGAGGTGAAC
GGCATTGAGGTGGCCGGGAAGACGCTGGACCAGGTCACGGACATGATGATCGCCAACAGC
CACAACCTCATCGTCACCGTCAAGCCCGCCAACCAGCGCAACAACGTGGTGCGCGGCGGC
CGCGCGTTGGGCAGCTCGGGACCGCCCTCGGACGGCACCGCGGGCTTCGTGGGTCCCCCC
GCCCCGCGCGTCCTGCAGAACTTCCACCCCGACGAGGCGGAGAGCGATGAGGACAACGAC
GTCGTCATCGAGGGCACACTGGAGCCTGCACGTCCCCCCCAGACCCCGGGCGCGCCCGCA
GGCAGCCTCTCCCGGGTCAATGGCGCGGGCCTGGCGCAGCGGCTGCAGCGGGACCTGGCC
CTGGACGGCGGCCTCCAGCGGCTGCTCAGCTCCCTGCGGGCCGACCCCCGTCACAGCCTG
GCGCTGCCGCCAGGCGGCGTGGAGGAGCACGGGCCCGCGGTCACGCTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 376 |
| Molecular Weight
| 40882.9 |
| Theoretical pI
| 8.37 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Partitioning defective 6 homolog gamma
MNRSFHKSQTLRFYDCSAVEVKSKFGAEFRRFSLDRHKPGKFEDFYKLVVHTHHISNSDV
TIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGA
LRDEGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASV
RVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANS
HNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDND
VVIEGTLEPARPPQTPGAPAGSLSRVNGAGLAQRLQRDLALDGGLQRLLSSLRADPRHSL
ALPPGGVEEHGPAVTL
|
| External Links |
|---|
| GenBank ID Protein
| 13537119 |
| UniProtKB/Swiss-Prot ID
| Q9BYG4 |
| UniProtKB/Swiss-Prot Entry Name
| PAR6G_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AB044556 |
| GeneCard ID
| PARD6G |
| GenAtlas ID
| PARD6G |
| HGNC ID
| HGNC:16076 |
| References |
|---|
| General References
| Not Available |