| Identification |
|---|
| HMDB Protein ID
| CDBP03702 |
| Secondary Accession Numbers
| Not Available |
| Name
| Nucleolar GTP-binding protein 1 |
| Description
| Not Available |
| Synonyms
|
- Chronic renal failure gene protein
- GTP-binding protein NGB
|
| Gene Name
| GTPBP4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| Involved in the biogenesis of the 60S ribosomal subunit |
| GO Classification
|
| Function |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| purine nucleotide binding |
|
| Cellular Location
|
- Nucleus
- nucleolus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10p15-p14 |
| SNPs
| GTPBP4 |
| Gene Sequence
|
>1905 bp
ATGGCACATTACAACTTCAAGAAAATTACGGTGGTGCCGTCCGCCAAGGACTTCATAGAC
CTCACGTTGTCGAAGACTCAACGAAAGACTCCAACCGTTATTCATAAACATTACCAAATA
CATCGCATTAGACATTTTTACATGAGAAAAGTCAAATTTACTCAACAGAATTACCATGAT
AGACTTTCACAAATTCTAACAGATTTCCCCAAATTGGATGATATTCATCCGTTCTATGCT
GATTTGATGAATATTCTCTACGACAAGGATCATTACAAGTTGGCTCTGGGGCAAATAAAT
ATTGCCAAAAATTTAGTGGACAATGTTGCTAAAGATTATGTGCGACTGATGAAGTATGGC
GACTCTCTCTACCGCTGCAAACAGCTGAAGCGTGCGGCCCTGGGACGGATGTGCACAGTG
ATCAAGAGGCAGAAGCAGAGTTTGGAGTATTTGGAGCAAGTGCGTCAGCATTTATCCCGT
TTGCCAACCATTGATCCGAATACCAGGACCCTGCTTTTGTGTGGGTACCCAAATGTTGGG
AAGTCCAGCTTCATCAACAAGGTGACGAGAGCAGACGTGGATGTCCAGCCCTATGCGTTC
ACAACCAAGTCTCTGTTTGTTGGGCACATGGATTATAAGTATCTACGTTGGCAGGTTGTA
GACACTCCTGGGATCCTGGACCACCCTCTGGAGGATAGGAACACCATCGAGATGCAGGCC
ATCACTGCCCTGGCCCACCTCCGTGCTGCGGTCCTGTATGTGATGGATTTGTCTGAGCAG
TGTGGGCATGGGCTGAGGGAGCAGCTAGAACTCTTCCAGAACATCAGACCTCTCTTCATC
AACAAGCCTCTCATAGTTGTAGCCAACAAATGTGATGTGAAGAGAATAGCTGAACTTTCT
GAAGATGATCAGAAAATATTTACAGATTTGCAGTCTGAAGGATTCCCTGTAATAGAGACC
AGCACCCTGACTGAGGAAGGTGTTATTAAAGTTAAAACAGAGGCTTGCGATAGGCTTTTG
GCTCATCGAGTGGAAACCAAAATGAAGGGAAATAAAGTGAATGAGGTGCTGAATAGACTG
CACCTGGCTATCCCAACCAGGAGGGACGATAAGGAGAGGCCCCCTTTCATCCCTGAAGGA
GTGGTGGCTCGCAGGAAGAGGATGGAAACTGAGGAGTCCAGGAAGAAGAGGGAACGAGAT
CTTGAGCTGGAAATGGGAGATGATTATATTTTGGATCTTCAGAAGTACTGGGATTTAATG
AATTTGTCTGAAAAACATGATAAGATACCAGAAATCTGGGAAGGCCATAATATAGCTGAT
TATATTGATCCAGCCATCATGAAGAAATTGGAAGAATTAGAAAAAGAAGAAGAGCTGAGA
ACAGCTGCTGGAGAGTATGACAGTGTATCTGAGAGTGAAGACGAAGAGATGCTGGAAATC
CGACAGCTGGCAAAGCAAATTCGAGAGAAAAAGAAGTTGAAAATTCTGGAGTCCAAAGAA
AAGAATACACAGGGACCCAGGATGCCGCGAACTGCTAAGAAGGTTCAGAGGACAGTTTTG
GAGAAGGAGATGCGTAGTCTTGGTGTTGACATGGACGATAAAGACGATGCCCATTACGCA
GTCCAGGCAAGAAGATCCCGGAGCATCACTAGGAAAAGAAAGCGGGAAGACTCTGCTCCC
CCGTCCTCTGTGGCCCGGAGTGGGAGTTGCTCTCGAACTCCACGTGACGTTTCTGGTCTT
AGGGATGTCAAGATGGTGAAGAAAGCCAAGACTATGATGAAGAATGCTCAGAAGAAGATG
AATCGGTTGGGGAAGAAAGGGGAGGCGGATAGACACGTGTTTGATATGAAGCCCAAGCAC
TTGCTGTCTGGGAAGAGGAAAGCTGGTAAAAAGGACAGGAGATAG
|
| Protein Properties |
|---|
| Number of Residues
| 634 |
| Molecular Weight
| 73963.9 |
| Theoretical pI
| 10.07 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Nucleolar GTP-binding protein 1
MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHD
RLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYG
DSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVG
KSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQA
ITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELS
EDDQKIFTDLQSEGFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGNKVNEVLNRL
HLAIPTRRDDKERPPFIPEGVVARRKRMETEESRKKRERDLELEMGDDYILDLQKYWDLM
NLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEKEEELRTAAGEYDSVSESEDEEMLEI
RQLAKQIREKKKLKILESKEKNTQGPRMPRTAKKVQRTVLEKEMRSLGVDMDDKDDAHYA
VQARRSRSITRKRKREDSAPPSSVARSGSCSRTPRDVSGLRDVKMVKKAKTMMKNAQKKM
NRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR
|
| External Links |
|---|
| GenBank ID Protein
| 55953087 |
| UniProtKB/Swiss-Prot ID
| Q9BZE4 |
| UniProtKB/Swiss-Prot Entry Name
| NOG1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_012341.2 |
| GeneCard ID
| GTPBP4 |
| GenAtlas ID
| GTPBP4 |
| HGNC ID
| HGNC:21535 |
| References |
|---|
| General References
| Not Available |