| Identification |
|---|
| HMDB Protein ID
| CDBP03696 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ran guanine nucleotide release factor |
| Description
| Not Available |
| Synonyms
|
- Ran-binding protein MOG1
- RanGNRF
|
| Gene Name
| RANGRF |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in guanyl-nucleotide exchange factor activity |
| Specific Function
| May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17p13.1 |
| SNPs
| RANGRF |
| Gene Sequence
|
>561 bp
ATGGAGCCCACGAGAGACTGCCCGCTGTTCGGGGGCGCCTTTTCCGCCATCCTCCCCATG
GGGGCCATTGACGTAAGCGACCTCCGACCGGTCCCGGACAATCAAGAAGTTTTCTGCCAT
CCCGTGACGGACCAGAGCCTGATAGTGGAACTTCTCGAGCTGCAGGCCCACGTACGGGGC
GAAGCGGCTGCGCGGTACCACTTTGAGGATGTTGGTGGCGTGCAGGGGGCTAGGGCTGTC
CATGTGGAGTCTGTTCAGCCTCTCAGTTTGGAGAACCTGGCCCTGAGGGGCCGCTGTCAA
GAAGCCTGGGTCCTCTCTGGCAAGCAGCAGATAGCTAAGGAAAACCAGCAGGTAGCAAAG
GACGTGACACTTCATCAGGCCTTGCTGAGGCTGCCCCAGTACCAGACTGATCTCTTGCTT
ACCTTCAATCAGCCCCCCCCTGACAACAGGTCATCTCTTGGCCCCGAAAATCTGTCACCT
GCACCCTGGAGCCTGGGTGACTTTGAACAGCTGGTGACCAGTCTGACCCTTCACGATCCT
AACATCTTTGGTCCCCAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 186 |
| Molecular Weight
| 20447.9 |
| Theoretical pI
| 4.57 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ran guanine nucleotide release factor
MEPTRDCPLFGGAFSAILPMGAIDVSDLRPVPDNQEVFCHPVTDQSLIVELLELQAHVRG
EAAARYHFEDVGGVQGARAVHVESVQPLSLENLALRGRCQEAWVLSGKQQIAKENQQVAK
DVTLHQALLRLPQYQTDLLLTFNQPPPDNRSSLGPENLSPAPWSLGDFEQLVTSLTLHDP
NIFGPQ
|
| External Links |
|---|
| GenBank ID Protein
| 41462397 |
| UniProtKB/Swiss-Prot ID
| Q9HD47 |
| UniProtKB/Swiss-Prot Entry Name
| MOG1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_016492.4 |
| GeneCard ID
| RANGRF |
| GenAtlas ID
| RANGRF |
| HGNC ID
| HGNC:17679 |
| References |
|---|
| General References
| Not Available |