| Identification |
|---|
| HMDB Protein ID
| CDBP03668 |
| Secondary Accession Numbers
| Not Available |
| Name
| Interferon-inducible GTPase 5 |
| Description
| Not Available |
| Synonyms
|
- Immunity-related GTPase cinema 1
|
| Gene Name
| IRGC |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| Not Available |
| GO Classification
|
| Cellular Component |
| membrane |
| Component |
| membrane |
| cell part |
| Function |
| hydrolase activity, acting on acid anhydrides |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| catalytic activity |
| hydrolase activity |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| Molecular Function |
| hydrolase activity, acting on acid anhydrides |
| GTP binding |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| 19q13.31 |
| SNPs
| IRGC |
| Gene Sequence
|
>1392 bp
ATGGCTACTTCAAAGTTGCCCGTGGTGCCTGGGGAGGAGGAAAACACCATCCTTATGGCC
AAGGAAAGGCTGGAGGCCCTGCGCACAGCCTTTGAGTCGGGTGACCTCCCCCAGGCCGCC
TCTCACCTCCAGGAGCTGCTGGCCTCCACGGAAAGCATCCGCCTGGAGGTGGGCGTCACG
GGCGAGTCGGGCGCGGGCAAGTCCTCCCTCATCAATGCCCTGCGTGGCCTGGAGGCCGAG
GACCCTGGCGCGGCTCTCACGGGCGTCATGGAGACCACGATGCAACCGTCGCCCTATCCA
CACCCACAGTTCCCTGACGTGACCCTCTGGGACCTGCCAGGAGCCGGCTCTCCAGGCTGC
CCGGCTGACAAGTACCTAAAGCAGGTAGACTTCAGCCGCTATGACTTCTTCCTGCTGGTC
TCCCCCCGCCGCTGCGGGGCCGTCGAGACCCGCCTGGCCGCTGAGATCCTGTGCCAGGGC
AAGAAGTTCTACTTTGTGCGCACCAAGGTGGACGAGGACCTGGCGGCCACGCGCACCCAG
CGGCCGTCGGGCTTCAGAGAGGCCGCTGTCCTGCAGGAGATCCGAGACCACTGTGCCGAG
CGGCTGCGGGAGGCCGGCGTGGCTGACCCTCGCATCTTCCTGGTGTCCAACCTCTCGCCG
GCCCGCTACGACTTTCCCACGCTGGTGTCCACCTGGGAGCACGACCTGCCCTCCCACCGG
CGCCACGCTGGCCTGCTGTCGCTCCCCGACATCTCGCTGGAGGCCTTGCAGAAGAAGAAG
GCCATGCTTCAAGAGCAAGTCCTCAAGACCGCCCTGGTGTTGGGCGTCATCCAGGCCCTG
CCGGTCCCAGGGCTGGCGGCCGCCTACGATGATGCGTTGCTCATCCACTCACTGCGTGGC
TACCACCGCAGCTTTGGTCTGGACGACGACTCGCTGGCCAAGCTGGCCGAGCAGGTGGGC
AAACAGGCAGGTGACCTGCGCTCGGTCATCCGCTCCCCACTGGCCAACGAGGTCTCGCCT
GAGACTGTCCTGCGGCTCTATTCCCAGTCGTCCGACGGCGCCATGCGGGTGGCCCGCGCC
TTTGAGAGGGGCATCCCTGTGTTTGGGACGCTGGTGGCTGGCGGCATCAGCTTTGGCGCT
GTCTACACCATGCTCCAGGGCTGCCTCAACGAGATGGCTGAGGACGCCCAGCGTGTCCGC
ATCAAGGCCCTGGAGGATGACGAGCCGCAGCCGGAGGTCAGCTTGGAAGTGGCCAGTGAC
AATGGCGTGGAAAAGGGGGGCTCCGGGGAGGGAGGTGGGGAGGAAGCCCCACTCTCAACC
TGCAGGAAGCTCGGCCTCCTTCTTAAGTACATTCTGGACAGCTGGAAGAAACACGACTCA
GAAGAGAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 463 |
| Molecular Weight
| 50287.62 |
| Theoretical pI
| 5.354 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Interferon-inducible GTPase 5
MATSKLPVVPGEEENTILMAKERLEALRTAFESGDLPQAASHLQELLASTESIRLEVGVT
GESGAGKSSLINALRGLEAEDPGAALTGVMETTMQPSPYPHPQFPDVTLWDLPGAGSPGC
PADKYLKQVDFSRYDFFLLVSPRRCGAVETRLAAEILCQGKKFYFVRTKVDEDLAATRTQ
RPSGFREAAVLQEIRDHCAERLREAGVADPRIFLVSNLSPARYDFPTLVSTWEHDLPSHR
RHAGLLSLPDISLEALQKKKAMLQEQVLKTALVLGVIQALPVPGLAAAYDDALLIHSLRG
YHRSFGLDDDSLAKLAEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVARA
FERGIPVFGTLVAGGISFGAVYTMLQGCLNEMAEDAQRVRIKALEDDEPQPEVSLEVASD
NGVEKGGSGEGGGEEAPLSTCRKLGLLLKYILDSWKKHDSEEK
|
| External Links |
|---|
| GenBank ID Protein
| 3548787 |
| UniProtKB/Swiss-Prot ID
| Q6NXR0 |
| UniProtKB/Swiss-Prot Entry Name
| IIGP5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC005622 |
| GeneCard ID
| IRGC |
| GenAtlas ID
| IRGC |
| HGNC ID
| HGNC:28835 |
| References |
|---|
| General References
| Not Available |