| Identification |
|---|
| HMDB Protein ID
| CDBP03657 |
| Secondary Accession Numbers
| Not Available |
| Name
| GTP-binding protein 10 |
| Description
| Not Available |
| Synonyms
|
- ObgH2
- Protein obg homolog 2
|
| Gene Name
| GTPBP10 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in magnesium ion binding |
| Specific Function
| May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| nucleotide binding |
| catalytic activity |
| hydrolase activity |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| magnesium ion binding |
| gtpase activity |
| nucleoside-triphosphatase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| ion binding |
| pyrophosphatase activity |
| cation binding |
| metal ion binding |
| purine nucleotide binding |
| binding |
|
| Cellular Location
|
- Nucleus
- nucleolus
- Chromosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q21.13 |
| SNPs
| GTPBP10 |
| Gene Sequence
|
>1164 bp
ATGGTGCATTGCAGTTGCGTGTTGTTCAGAAAGTATGGAAATTTCATCGATAAGCTAAGA
CTCTTCACCAGGGGAGGATCCGGTGGAATGGGTTATCCTCGTTTAGGTGGAGAAGGTGGA
AAAGGTGGTGATGTCTGGGTTGTAGCCCAGAACAGAATGACTTTAAAACAACTTAAAGAC
AGGTATCCTCGGAAACGGTTTGTGGCTGGAGTAGGAGCAAACAGCAAAATTAGTGCACTG
AAAGGCTCCAAAGGAAAAGACTGTGAAATCCCTGTGCCTGTGGGTATTTCAGTAACTGAT
GAAAATGGTAAAATTATAGGAGAACTCAATAAAGAAAATGACAGAATTTTGGTAGCTCAA
GGAGGTCTTGGTGGTAAATTACTTACAAATTTCTTACCATTGAAAGGCCAGAAACGAATA
ATTCACCTTGATCTAAAACTTATAGCTGATGTAGGCCTAGTAGGATTCCCAAATGCTGGA
AAATCCTCTTTGCTAAGTTGTGTTTCTCATGCAAAACCTGCAATTGCAGATTACGCATTT
ACAACATTAAAGCCTGAACTTGGAAAGATAATGTACAGTGATTTCAAACAGATATCAGTA
GCTGATCTTCCGGGTTTAATAGAAGGAGCACATATGAACAAAGGAATGGGCCACAAATTC
CTCAAGCATATAGAAAGAACTAGACAACTACTTTTTGTTGTTGATATTTCTGGATTTCAG
CTTTCTTCTCACACTCAATACAGGACAGCTTTTGAAACCATAATACTGCTTACAAAAGAG
TTGGAATTGTACAAAGAGGAACTTCAGACAAAACCTGCACTCTTGGCAGTTAATAAAATG
GACTTGCCAGATGCCCAAGATAAGTTCCATGAATTGATGAGCCAGCTCCAGAATCCTAAA
GATTTTCTGCATTTATTTGAAAAAAACATGATTCCAGAGAGGACTGTAGAGTTCCAACAT
ATCATCCCCATATCTGCAGTTACTGGAGAAGGAATCGAAGAATTAAAGAATTGTATAAGA
AAGTCACTGGATGAACAGGCCAACCAGGAAAATGATGCACTTCATAAGAAACAGTTGCTT
AATTTGTGGATTTCTGATACAATGTCTTCTACTGAGCCACCATCAAAGCATGCTGTTACT
ACTTCCAAAATGGATATAATTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 387 |
| Molecular Weight
| 42932.6 |
| Theoretical pI
| 9.55 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>GTP-binding protein 10
MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKD
RYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQ
GGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAF
TTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQ
LSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPK
DFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLL
NLWISDTMSSTEPPSKHAVTTSKMDII
|
| External Links |
|---|
| GenBank ID Protein
| 111955139 |
| UniProtKB/Swiss-Prot ID
| A4D1E9 |
| UniProtKB/Swiss-Prot Entry Name
| GTPBA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_033107.2 |
| GeneCard ID
| GTPBP10 |
| GenAtlas ID
| GTPBP10 |
| HGNC ID
| HGNC:25106 |
| References |
|---|
| General References
| Not Available |