| Identification |
|---|
| HMDB Protein ID
| CDBP03655 |
| Secondary Accession Numbers
| Not Available |
| Name
| GTP-binding protein 5 |
| Description
| Not Available |
| Synonyms
|
- ObgH1
- Protein obg homolog 1
|
| Gene Name
| GTPBP5 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in magnesium ion binding |
| Specific Function
| Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| nucleoside-triphosphatase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| pyrophosphatase activity |
| ion binding |
| cation binding |
| metal ion binding |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| catalytic activity |
| hydrolase activity |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| magnesium ion binding |
| gtpase activity |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20q13.33 |
| SNPs
| GTPBP5 |
| Gene Sequence
|
>1221 bp
ATGGCACCTGCAAGGTGTTTCTCAGCAAGATTGAGGACCGTGTTTCAGGGCGTGGGGCAT
TGGGCTTTGTCCACATGGGCTGGCCTGAAGCCCAGCCGGCTACTGCCACAGCGGGCTTCT
CCCAGGCTGCTCTCGGTCGGCCGTGCGGACCTCGCCAAGCATCAGGAACTCCCGGGGAAG
AAGCTGCTCTCTGAGAAAAAGCTGAAAAGGTACTTTGTGGACTATCGGAGAGTGCTTGTC
TGTGGAGGAAACGGAGGCGCTGGGGCAAGCTGCTTCCACAGTGAGCCCCGCAAGGAGTTT
GGAGGCCCTGATGGAGGGGACGGAGGCAACGGTGGACACGTCATTCTGAGAGTTGACCAG
CAAGTCAAGTCCCTGTCGTCGGTCCTGTCGCGGTACCAGGGTTTCAGTGGAGAAGATGGA
GGGAGTAAAAACTGCTTCGGGCGCAGTGGCGCCGTCCTCTACATCCGGGTCCCCGTGGGC
ACGCTGGTGAAGGAGGGAGGCAGAGTTGTGGCCGACCTGTCTTGCGTGGGAGATGAGTAC
ATTGCCGCGCTGGGCGGGGCAGGAGGGAAAGGCAACCGCTTCTTCCTGGCCAACAACAAC
CGTGCCCCTGTGACCTGTACCCCTGGACAGCCAGGACAGCAGCGAGTTCTCCACCTGGAG
CTCAAGACGGTGGCCCACGCCGGAATGGTGGGATTCCCCAACGCCGGGAAGTCCTCACTG
CTCCGGGCCATTTCAAACGCCAGACCCGCCGTGGCTTCCTACCCGTTCACCACCCTGAAG
CCCCACGTCGGGATCGTCCACTACGAAGGCCACCTACAAATAGCAGTGGCCGACATCCCC
GGCATCATACGAGGCGCCCACCAGAACAGGGGTCTGGGGTCCGCCTTCCTCAGGCACATC
GAGCGCTGCCGCTTTCTCTTGTTCGTGGTGGATCTTTCTCAGCCTGAGCCGTGGACTCAA
GTTGACGATTTAAAATATGAACTGGAGATGTATGAAAAGGGCCTGTCTGCGAGGCCCCAC
GCAATCGTCGCAAACAAGATTGACCTCCCTGAAGCCCAAGCCAATCTGTCCCAGCTCCGG
GATCACTTGGGACAGGAGGTCATCGTGCTGTCGGCGTTGACCGGCGAGAACCTGGAGCAG
CTGCTGTTGCACCTGAAGGTGCTGTATGACGCCTACGCGGAGGCCGAGCTGGGCCAGGGC
CGCCAGCCGCTCAGGTGGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 406 |
| Molecular Weight
| 43955.1 |
| Theoretical pI
| 9.89 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>GTP-binding protein 5
MAPARCFSARLRTVFQGVGHWALSTWAGLKPSRLLPQRASPRLLSVGRADLAKHQELPGK
KLLSEKKLKRYFVDYRRVLVCGGNGGAGASCFHSEPRKEFGGPDGGDGGNGGHVILRVDQ
QVKSLSSVLSRYQGFSGEDGGSKNCFGRSGAVLYIRVPVGTLVKEGGRVVADLSCVGDEY
IAALGGAGGKGNRFFLANNNRAPVTCTPGQPGQQRVLHLELKTVAHAGMVGFPNAGKSSL
LRAISNARPAVASYPFTTLKPHVGIVHYEGHLQIAVADIPGIIRGAHQNRGLGSAFLRHI
ERCRFLLFVVDLSQPEPWTQVDDLKYELEMYEKGLSARPHAIVANKIDLPEAQANLSQLR
DHLGQEVIVLSALTGENLEQLLLHLKVLYDAYAEAELGQGRQPLRW
|
| External Links |
|---|
| GenBank ID Protein
| 24308117 |
| UniProtKB/Swiss-Prot ID
| Q9H4K7 |
| UniProtKB/Swiss-Prot Entry Name
| GTPB5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015666.3 |
| GeneCard ID
| GTPBP5 |
| GenAtlas ID
| GTPBP5 |
| HGNC ID
| HGNC:16239 |
| References |
|---|
| General References
| Not Available |