Cannabis Compound Database: Showing Protein ADP-ribosylation factor-binding protein GGA3 (CDBP03636)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03636

Secondary Accession Numbers

Not Available

Name

ADP-ribosylation factor-binding protein GGA3

Description

Not Available

Synonyms

Golgi-localized, gamma ear-containing, ARF-binding protein 3

Gene Name

GGA3

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein binding

Specific Function

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif

GO Classification

Component
intracellular part
macromolecular complex
protein complex
cytoplasmic part
ap-type membrane coat adaptor complex
intracellular
clathrin adaptor complex
membrane coat
golgi apparatus part
cell part
Function
binding
protein binding
Process
establishment of localization
transport
protein transport
intracellular protein transport
vesicle-mediated transport

Cellular Location

Peripheral membrane protein
Peripheral membrane protein
Endosome membrane
Golgi apparatus
trans-Golgi network membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

17q25.1

SNPs

GGA3

Gene Sequence

>2172 bp
ATGGCGGAGGCGGAAGGGGAAAGCCTGGAGTCCTGGCTCAATAAAGCCACCAATCCTTCC
AACCGCCAGGAGGACTGGGAATACATAATTGGCTTCTGTGATCAGATCAACAAGGAGCTG
GAAGGGCCACAGATCGCCGTCCGACTGCTGGCCCACAAGATCCAGTCCCCACAGGAATGG
GAGGCGCTCCAGGCCCTGACGGTGCTGGAGGCATGCATGAAGAACTGTGGGAGGAGATTT
CATAACGAAGTGGGGAAGTTCCGCTTTTTGAATGAGTTAATCAAAGTCGTCTCTCCAAAG
TACCTGGGGGACAGGGTGTCTGAGAAAGTGAAGACCAAGGTTATTGAGCTGCTGTACAGC
TGGACCATGGCCCTGCCAGAAGAAGCAAAGATCAAAGACGCCTACCACATGCTGAAGAGA
CAGGGCATAGTGCAGTCTGACCCACCAATTCCTGTGGATAGGACGCTGATCCCCTCTCCA
CCACCTCGTCCCAAAAACCCTGTTTTTGATGATGAGGAGAAGTCCAAGCTTTTAGCCAAG
CTGCTGAAAAGCAAAAACCCAGATGACCTGCAGGAGGCCAACAAGCTCATCAAGTCCATG
GTGAAGGAAGACGAGGCACGGATCCAGAAGGTGACCAAGCGTCTGCACACGTTAGAGGAA
GTTAACAACAACGTGAGACTGCTCAGTGAGATGCTGCTTCATTACAGCCAGGAGGACTCT
TCGGACGGGGACAGAGAGCTGATGAAGGAGCTGTTTGATCAGTGTGAGAACAAGAGGCGG
ACTTTATTTAAACTCGCCAGTGAGACTGAGGACAATGATAACAGTTTGGGGGACATCCTG
CAAGCCAGTGACAACCTCTCCCGGGTCATCAACTCTTACAAAACAATTATTGAAGGGCAG
GTCATCAATGGCGAGGTGGCTACCTTAACCCTGCCTGACTCGGAAGGAAACAGTCAGTGC
AGTAACCAAGGCACGCTCATCGACCTTGCGGAGCTGGACACGACCAACAGTTTGTCCTCC
GTGTTGGCCCCAGCACCTACTCCACCCTCCTCAGGCATCCCAATCCTCCCTCCACCACCC
CAGGCCTCAGGACCTCCACGGAGCCGCTCCTCTAGCCAGGCCGAGGCCACCCTGGGGCCC
AGCAGCACAAGCAACGCCCTCTCCTGGCTGGACGAGGAGCTACTCTGCTTGGGCCTCGCC
GACCCAGCCCCTAATGTTCCTCCCAAAGAGTCAGCTGGGAACAGCCAGTGGCACCTGCTC
CAGAGGGAACAGTCCGACCTGGACTTCTTCAGCCCCAGGCCGGGGACCGCTGCCTGTGGC
GCCTCCGATGCTCCTCTGCTCCAGCCCTCAGCCCCCTCCTCAAGCAGCTCCCAAGCTCCA
CTGCCGCCTCCCTTCCCAGCTCCTGTGGTCCCAGCCAGTGTTCCTGCCCCCAGTGCGGGC
TCCTCCTTGTTTTCTACTGGAGTGGCCCCAGCCTTGGCCCCAAAAGTTGAGCCCGCAGTC
CCTGGGCACCATGGCTTGGCGTTGGGCAACAGCGCGCTGCACCACCTGGATGCCCTCGAT
CAGCTTCTAGAAGAGGCCAAAGTGACCTCGGGCTTGGTGAAACCCACTACCTCCCCTCTC
ATCCCCACCACCACCCCAGCCAGGCCCCTCCTGCCCTTCTCCACGGGGCCCGGCAGCCCG
CTCTTCCAGCCACTGAGTTTCCAGTCCCAGGGCAGCCCCCCGAAGGGGCCTGAGCTCTCC
CTGGCCAGCATCCACGTGCCCCTGGAATCGATCAAGCCTAGCAGTGCCCTTCCTGTGACA
GCCTACGATAAAAACGGCTTCCGCATCCTCTTCCACTTTGCCAAGGAGTGTCCCCCAGGA
CGACCTGACGTGCTGGTGGTGGTGGTGTCCATGCTGAACACGGCTCCCTTACCTGTCAAG
AGCATCGTGCTGCAGGCTGCAGTGCCCAAGTCAATGAAAGTGAAGTTGCAGCCACCTTCT
GGGACAGAACTCTCTCCATTTAGCCCCATCCAGCCACCTGCAGCCATCACCCAGGTCATG
TTGCTGGCCAATCCACTGAAGGAGAAGGTGCGGCTTCGGTATAAGCTGACCTTCGCCCTG
GGGGAGCAGCTGAGCACAGAGGTGGGCGAGGTGGACCAGTTCCCTCCTGTGGAACAGTGG
GGGAACCTATGA

Protein Properties

Number of Residues

723

Molecular Weight

78314.5

Theoretical pI

5.27

Pfam Domain Function

Alpha_adaptinC2 (PF02883 )
GAT (PF03127 )
VHS (PF00790 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>ADP-ribosylation factor-binding protein GGA3
MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW
EALQALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYS
WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK
LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS
SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ
VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP
QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL
QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG
SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL
IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT
AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS
GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW
GNL

External Links

GenBank ID Protein

20336267

UniProtKB/Swiss-Prot ID

Q9NZ52

UniProtKB/Swiss-Prot Entry Name

GGA3_HUMAN

PDB IDs