Cannabis Compound Database: Showing Protein ADP-ribosylation factor-binding protein GGA1 (CDBP03634)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03634

Secondary Accession Numbers

Not Available

Name

ADP-ribosylation factor-binding protein GGA1

Description

Not Available

Synonyms

Gamma-adaptin-related protein 1
Golgi-localized, gamma ear-containing, ARF-binding protein 1

Gene Name

GGA1

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein binding

Specific Function

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif

GO Classification

Component
membrane coat
golgi apparatus part
cell part
intracellular part
macromolecular complex
protein complex
cytoplasmic part
ap-type membrane coat adaptor complex
intracellular
clathrin adaptor complex
Function
binding
protein binding
Process
vesicle-mediated transport
establishment of localization
transport
protein transport
intracellular protein transport

Cellular Location

Peripheral membrane protein
Peripheral membrane protein
Endosome membrane
Golgi apparatus
trans-Golgi network membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:2

Locus

22q13.31

SNPs

GGA1

Gene Sequence

>1920 bp
ATGGAGCCCGCGATGGAGCCGGAGACTCTGGAGGCGCGAATCAATAGAGCCACGAACCCC
CTGAACAAGGAGCTCGACTGGGCCAGCATCAACGGCTTCTGCGAGCAGCTCAACGAGGAC
TTTGAGGGGCCTCCACTCGCCACCCGGCTGCTGGCCCACAAGATCCAGTCCCCACAGGAG
TGGGAGGCGATCCAGGCCTTGACGGTGCTGGAAACATGCATGAAGAGCTGCGGCAAGCGG
TTCCACGACGAAGTGGGCAAGTTCCGCTTTCTCAACGAGCTCATCAAGGTCGTGTCTCCC
AAGTATCTGGGCTCTCGGACATCGGAGAAGGTGAAGAACAAGATCTTGGAGCTCCTCTAC
AGCTGGACAGTGGGCCTGCCCGAGGAGGTGAAAATCGCAGAGGCCTACCAGATGCTAAAG
AAGCAGGGGATTGTAAAGTCCGACCCCAAGCTTCCAGATGACACTACCTTTCCCCTTCCT
CCTCCACGGCCGAAGAATGTGATCTTTGAAGATGAGGAGAAATCCAAGATGCTGGCCCGC
CTGCTGAAGAGCTCCCATCCCGAAGACCTCCGCGCAGCCAATAAGCTCATCAAAGAGATG
GTGCAGGAGGACCAGAAGCGGATGGAGAAGATCTCGAAGAGGGTGAATGCCATCGAGGAG
GTGAACAACAATGTGAAACTGCTCACGGAGATGGTGATGAGCCACAGCCAGGGCGGCGCA
GCAGCTGGCAGCAGCGAGGACCTCATGAAGGAACTGTACCAGCGCTGTGAGCGGATGCGG
CCCACGCTCTTCCGACTGGCGAGTGACACAGAGGACAATGATGAGGCCTTAGCGGAGATC
CTGCAGGCCAATGACAACCTCACCCAGGTGATCAACCTGTATAAGCAGCTGGTGCGGGGT
GAGGAGGTCAACGGTGATGCCACAGCCGGCTCCATCCCTGGGAGCACCTCGGCCCTGCTG
GATCTCTCAGGCCTGGATCTCCCGCCTGCGGGCACCACCTACCCAGCTATGCCCACCCGC
CCTGGCGAGCAGGCCAGCCCTGAGCAACCCAGTGCCTCAGTTTCCCTGCTTGACGACGAG
CTCATGTCTCTGGGCCTCAGTGACCCCACACCCCCTTCAGGCCCAAGCCTGGATGGTACC
GGATGGAACAGCTTCCAGTCGTCGGATGCCACTGAGCCCCCAGCCCCTGCTCTGGCCCAG
GCCCCCAGTATGGAAAGCCGACCCCCAGCGCAGACATCCCTGCCAGCAAGCAGCGGTCTG
GACGACCTAGACCTCCTGGGGAAGACCCTCCTGCAGCAGTCGCTGCCCCCGGAATCCCAG
CAAGTGCGGTGGGAGAAGCAGCAGCCAACCCCCCGGCTCACACTCCGGGACCTGCAGAAT
AAGAGCAGCAGCTGCAGCTCCCCCAGCTCCAGCGCCACCAGCCTTCTCCACACCGTGTCC
CCAGAGCCCCCCAGGCCTCCGCAGCAGCCCGTACCAACCGAGCTCTCACTGGCCAGCATC
ACTGTGCCCCTGGAGTCCATCAAACCCAGCAACATCCTGCCCGTGACTGTGTATGACCAG
CACGGCTTCCGCATCCTCTTCCATTTTGCCCGGGACCCACTGCCAGGGCGCTCCGACGTG
CTGGTGGTGGTGGTTTCCATGCTGAGCACCGCCCCCCAGCCCATCCGCAACATCGTGTTC
CAGTCAGCTGTCCCCAAGGTTATGAAGGTGAAGCTGCAGCCACCCTCGGGCACGGAGCTG
CCAGCTTTTAACCCCATCGTCCACCCCTCAGCAATCACCCAGGTCCTGCTGCTTGCCAAC
CCCCAGAAGGAGAAGGTTCGCCTCCGCTACAAGCTCACCTTCACCATGGGTGACCAGACC
TACAACGAGATGGGGGATGTGGACCAGTTCCCCCCACCTGAAACCTGGGGTAGCCTCTAG

Protein Properties

Number of Residues

639

Molecular Weight

70383.5

Theoretical pI

4.93

Pfam Domain Function

Alpha_adaptinC2 (PF02883 )
GAT (PF03127 )
VHS (PF00790 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>ADP-ribosylation factor-binding protein GGA1
MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY
SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR
LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA
AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG
EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDE
LMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL
DDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVS
PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDV
LVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLAN
PQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL

External Links

GenBank ID Protein

6179912

UniProtKB/Swiss-Prot ID

Q9UJY5

UniProtKB/Swiss-Prot Entry Name

GGA1_HUMAN

PDB IDs