Cannabis Compound Database: Showing Protein Guanylate-binding protein 3 (CDBP03630)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03630

Secondary Accession Numbers

Not Available

Name

Guanylate-binding protein 3

Description

Not Available

Synonyms

GBP-3
GTP-binding protein 3
Guanine nucleotide-binding protein 3

Gene Name

GBP3

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTPase activity

Specific Function

Binds GTP, GDP and GMP

GO Classification

Function
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding

Cellular Location

Membrane
Multi-pass membrane protein (Potential)

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1p22.2

SNPs

GBP3

Gene Sequence

>1788 bp
ATGGCTCCAGAGATCCACATGACAGGCCCAATGTGCCTCATTGAGAACACTAATGGGGAA
CTGGTGGCGAATCCAGAAGCTCTGAAAATCCTGTCTGCCATTACACAGCCTGTGGTGGTG
GTGGCAATTGTGGGCCTCTACCGCACAGGAAAATCCTACCTGATGAACAAGCTAGCTGGG
AAGAATAAGGGCTTCTCTCTGGGCTCCACAGTGAAATCTCACACCAAAGGAATCTGGATG
TGGTGTGTGCCTCACCCCAAAAAGCCAGAACACACCTTAGTCCTGCTTGACACTGAGGGC
CTGGGAGATGTAAAGAAGGGTGACAACCAGAATGACTCCTGGATCTTCACCCTGGCCGTC
CTCCTGAGCAGCACTCTCGTGTACAATAGCATGGGAACCATCAACCAGCAGGCTATGGAC
CAACTGTACTATGTGACAGAGCTGACACATCGAATCCGATCAAAATCCTCACCTGATGAG
AATGAGAATGAGGATTCAGCTGACTTTGTGAGCTTCTTCCCAGATTTTGTGTGGACACTG
AGAGATTTCTCCCTGGACTTGGAAGCAGATGGACAACCCCTCACACCAGATGAGTACCTG
GAGTATTCCCTGAAGCTAACGCAAGGTACCAGTCAAAAAGATAAAAATTTTAATCTGCCC
CGACTCTGTATCCGGAAGTTCTTCCCAAAGAAAAAATGTTTTGTCTTCGATCTGCCCATT
CACCGCAGGAAGCTTGCCCAGCTTGAGAAACTACAAGATGAAGAGCTGGACCCTGAATTT
GTGCAACAAGTAGCAGACTTCTGTTCCTACATCTTTAGCAATTCCAAAACTAAAACTCTT
TCAGGAGGCATCAAGGTCAATGGGCCTCGTCTAGAGAGCCTAGTGCTGACCTATATCAAT
GCTATCAGCAGAGGGGATCTGCCCTGCATGGAGAACGCAGTCCTGGCCTTGGCCCAGATA
GAGAACTCAGCCGCAGTGCAAAAGGCTATTGCCCACTATGACCAGCAGATGGGCCAGAAG
GTGCAGCTGCCCGCAGAAACCCTCCAGGAGCTGCTGGACCTGCACAGGGTTAGTGAGAGG
GAGGCCACTGAAGTCTATATGAAGAACTCTTTCAAGGATGTGGACCATCTGTTTCAAAAG
AAATTAGCGGCCCAGCTAGACAAAAAGCGGGATGACTTTTGTAAACAGAATCAAGAAGCA
TCATCAGATCGTTGCTCAGCTTTACTTCAGGTCATTTTCAGTCCTCTAGAAGAAGAAGTG
AAGGCGGGAATTTATTCGAAACCAGGGGGCTATTGTCTCTTTATTCAGAAGCTACAAGAC
CTGGAGAAAAAGTACTATGAGGAACCAAGGAAGGGGATACAGGCTGAAGAGATTCTGCAG
ACATACTTGAAATCCAAGGAGTCTGTGACCGATGCAATTCTACAGACAGACCAGATTCTC
ACAGAAAAGGAAAAGGAGATTGAAGTGGAATGTGTAAAAGCTGAATCTGCACAGGCTTCA
GCAAAAATGGTGGAGGAAATGCAAATAAAGTATCAGCAGATGATGGAAGAGAAAGAGAAG
AGTTATCAAGAACATGTGAAACAATTGACTGAGAAGATGGAGAGGGAGAGGGCCCAGTTG
CTGGAAGAGCAAGAGAAGACCCTCACTAGTAAACTTCAGGAACAGGCCCGAGTACTAAAG
GAGAGATGCCAAGGTGAAAGTACCCAACTTCAAAATGAGATACAAAAGCTACAGAAGACC
CTGAAAAAAAAAACCAAGAGATATATGTCGCATAAGCTAAAGATCTAA

Protein Properties

Number of Residues

595

Molecular Weight

68113.6

Theoretical pI

6.46

Pfam Domain Function

GBP (PF02263 )
GBP_C (PF02841 )

Signals

["None"]

Transmembrane Regions

["27-47", "114-134"]

Protein Sequence

>Guanylate-binding protein 3
MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAG
KNKGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAV
LLSSTLVYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTL
RDFSLDLEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPI
HRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYIN
AISRGDLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSER
EATEVYMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEV
KAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQIL
TEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQL
LEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKKTKRYMSHKLKI

External Links

GenBank ID Protein

112382372

UniProtKB/Swiss-Prot ID

Q9H0R5

UniProtKB/Swiss-Prot Entry Name

GBP3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_018284.2

GeneCard ID