| Identification |
|---|
| HMDB Protein ID
| CDBP03615 |
| Secondary Accession Numbers
| Not Available |
| Name
| Guanine nucleotide-binding protein subunit beta-4 |
| Description
| Not Available |
| Synonyms
|
- Transducin beta chain 4
|
| Gene Name
| GNB4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transducer activity |
| Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q26.33 |
| SNPs
| GNB4 |
| Gene Sequence
|
>1023 bp
ATGAGCGAGCTGGAGCAGCTGAGGCAGGAGGCTGAACAGCTTCGGAATCAGATCCAGGAT
GCTCGGAAGGCCTGCAATGATGCCACGCTGGTTCAGATCACGTCTAATATGGACTCCGTG
GGCCGAATACAAATGCGAACAAGGCGCACGCTGCGCGGCCACCTCGCTAAGATCTACGCC
ATGCACTGGGGATATGATTCCAGGCTACTAGTCAGTGCTTCGCAAGATGGAAAATTAATT
ATTTGGGATAGCTATACGACAAATAAGATGCACGCCATCCCTCTGAGGTCCTCCTGGGTG
ATGACCTGTGCCTACGCCCCGTCCGGGAACTACGTTGCCTGTGGAGGCTTGGATAACATC
TGCTCCATATACAACCTAAAGACCCGAGAGGGGAATGTGCGGGTGAGCCGAGAATTGCCA
GGACACACGGGCTACTTGTCCTGCTGCCGATTCTTAGATGATGGACAAATCATTACAAGT
TCGGGAGACACGACTTGTGCTTTGTGGGACATTGAGACCGGACAGCAGACTACGACCTTC
ACGGGACACTCGGGTGACGTGATGAGCCTCTCACTGAGTCCTGACTTGAAGACCTTTGTG
TCTGGTGCTTGTGATGCATCCTCAAAGCTGTGGGATATCCGAGATGGGATGTGTAGACAG
TCTTTCACCGGACACATCTCAGACATCAACGCTGTCAGTTTCTTCCCGAGTGTATATGCC
TTTGCCACTGGTTCTGATGATGCCACATGCCGACTCTTTGACCTCCGTGCAGACCAGGAG
CTCCTGCTATACTCTCATGACAATATCATCTGTGGCATTACTTCTGTGGCCTTCTCAAAG
AGTGGGCGCCTCCTGTTAGCCGGCTATGACGACTTCAACTGCAGTGTGTGGGACGCTCTG
AAAGGAGGCCGGTCAGGTGTCCTTGCTGGTCATGACAACCGTGTTAGCTGCTTAGGTGTG
ACTGATGACGGCATGGCTGTGGCCACTGGCTCCTGGGACAGTTTTCTTAGAATCTGGAAT
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 340 |
| Molecular Weight
| 37566.8 |
| Theoretical pI
| 5.85 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Guanine nucleotide-binding protein subunit beta-4
MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYA
MHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTF
TGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYA
FATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
|
| External Links |
|---|
| GenBank ID Protein
| 20257506 |
| UniProtKB/Swiss-Prot ID
| Q9HAV0 |
| UniProtKB/Swiss-Prot Entry Name
| GBB4_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF501886 |
| GeneCard ID
| GNB4 |
| GenAtlas ID
| GNB4 |
| HGNC ID
| HGNC:20731 |
| References |
|---|
| General References
| Not Available |