| Identification |
|---|
| HMDB Protein ID
| CDBP03601 |
| Secondary Accession Numbers
| Not Available |
| Name
| Exocyst complex component 8 |
| Description
| Not Available |
| Synonyms
|
- Exocyst complex 84 kDa subunit
|
| Gene Name
| EXOC8 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Component of the exocyst complex involved in the docking of exocystic vesicles with fusion sites on the plasma membrane |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Cell projection
- growth cone
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q42.2 |
| SNPs
| EXOC8 |
| Gene Sequence
|
>2178 bp
ATGGCGATGGCGATGTCGGACAGTGGGGCGAGCCGCCTGCGTCGGCAGCTGGAGTCAGGG
GGTTTTGAGGCGCGGCTGTACGTGAAGCAGCTCTCGCAGCAGTCGGATGGGGACCGGGAC
CTCCAGGAGCACCGGCAGCGCATCCAGGCGCTGGCGGAGGAGACGGCGCAGAACCTGAAG
CGCAACGTCTACCAGAACTACCGGCAGTTCATAGAGACGGCCCGCGAGATCTCCTACCTG
GAGAGCGAGATGTACCAGCTCAGCCATTTGCTGACCGAGCAGAAAAGCAGCCTGGAGAGC
ATCCCGCTTACGTTGCTGCCTGCCGCTGCTGCCGCCGGAGCCGCCGCCGCCTCTGGAGGG
GAGGAGGGAGTCGGTGGGGCGGGGGGCCGAGACCACCTCCGAGGCCAGGCCGGCTTTTTC
TCCACCCCCGGGGGTGCCTCCCGCGACGGCTCCGGTCCAGGCGAGGAAGGAAAGCAGCGC
ACTCTCACCACCCTGCTTGAGAAGGTGGAAGGCTGCAGGCATCTGCTGGAGACGCCGGGA
CAGTACTTGGTGTACAATGGGGACCTAGTGGAATACGATGCGGACCACATGGCCCAACTG
CAGCGGGTGCACGGCTTTCTCATGAACGATTGCTTGTTGGTGGCTACCTGGCTGCCTCAG
CGGCGTGGGATGTATCGCTACAACGCTCTCTATTCCCTAGATGGTTTGGCCGTAGTCAAT
GTCAAGGACAACCCGCCCATGAAGGACATGTTCAAGCTGCTTATGTTCCCCGAGAGCCGT
ATTTTCCAGGCCGAAAATGCTAAAATCAAACGAGAGTGGCTGGAAGTGCTGGAGGACACC
AAGAGGGCCCTCAGTGAGAAAAGGCGAAGGGAGCAGGAGGAGGCAGCGGCCCCTCGAGGG
CCACCCCAAGTGACTTCCAAGGCCACTAACCCATTTGAGGATGACGAAGAAGAAGAACCA
GCTGTTCCTGAGGTAGAGGAAGAGAAGGTGGACCTCTCCATGGAATGGATCCAGGAGTTA
CCTGAAGACCTGGATGTCTGCATTGCGCAGAGAGACTTTGAAGGGGCGGTTGACCTGCTG
GATAAATTGAACCATTACCTGGAAGATAAACCTAGCCCACCTCCTGTAAAAGAACTAAGG
GCCAAAGTGGAGGAGCGAGTTCGACAGCTCACTGAGGTGCTAGTTTTCGAACTCTCCCCA
GATCGTTCCCTGAGAGGTGGTCCGAAGGCTACTCGCAGAGCAGTTTCGCAACTGATCCGG
CTGGGCCAGTGCACGAAGGCCTGTGAGCTATTTTTGAGAAACAGGGCAGCCGCTGTTCAT
ACTGCAATTCGTCAGCTTCGCATCGAAGGTGCCACTTTACTCTATATTCATAAGCTGTGC
CATGTCTTCTTTACCAGCCTTCTCGAGACTGCAAGAGAATTTGAGATCGATTTTGCAGGC
ACTGACAGCGGCTGCTACTCTGCCTTTGTGGTCTGGGCAAGATCAGCCATGGGCATGTTC
GTGGATGCTTTTAGCAAGCAGGTGTTTGATAGTAAGGAGAGCCTCTCTACAGCAGCTGAG
TGTGTAAAAGTGGCTAAGGAGCATTGCCAGCAACTGGGTGATATCGGACTGGATCTCACC
TTCATCATCCATGCCCTTCTGGTGAAAGACATCCAAGGGGCCTTGCACAGTTACAAAGAA
ATCATCATTGAAGCCACTAAACATCGCAACTCTGAAGAGATGTGGAGGAGGATGAACTTG
ATGACGCCAGAAGCCCTGGGTAAGCTCAAAGAAGAGATGAAAAGTTGTGGGGTAAGTAAC
TTTGAGCAGTACACAGGGGATGACTGCTGGGTGAACCTAAGTTACACAGTGGTTGCTTTC
ACCAAACAGACCATGGGCTTCTTGGAAGAGGCCCTGAAGCTGTATTTCCCAGAGCTGCAC
ATGGTACTTTTGGAGAGCCTGGTGGAAATCATTTTGGTTGCTGTTCAGCATGTGGATTAT
AGTCTTCGATGTGAGCAGGATCCAGAGAAGAAAGCTTTTATCAGACAGAATGCATCCTTT
TTATATGAAACAGTCCTCCCTGTGGTGGAGAAAAGGTTTGAAGAAGGTGTGGGGAAACCT
GCCAAGCAACTCCAAGATCTGAGGAATGCATCTAGACTTATTCGTGTGAATCCTGAAAGT
ACAACATCAGTGGTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 725 |
| Molecular Weight
| 81798.4 |
| Theoretical pI
| 5.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Exocyst complex component 8
MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLK
RNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGG
EEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPG
QYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVN
VKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRG
PPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLL
DKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIR
LGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAG
TDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGDIGLDLT
FIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSN
FEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDY
SLRCEQDPEKKAFIRQNASFLYETVLPVVEKRFEEGVGKPAKQLQDLRNASRLIRVNPES
TTSVV
|
| External Links |
|---|
| GenBank ID Protein
| 193788401 |
| UniProtKB/Swiss-Prot ID
| Q8IYI6 |
| UniProtKB/Swiss-Prot Entry Name
| EXOC8_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK096460 |
| GeneCard ID
| EXOC8 |
| GenAtlas ID
| EXOC8 |
| HGNC ID
| HGNC:24659 |
| References |
|---|
| General References
| Not Available |