| Identification |
| HMDB Protein ID
| CDBP03598 |
| Secondary Accession Numbers
| Not Available |
| Name
| Elongation factor Tu GTP-binding domain-containing protein 1 |
| Description
| Not Available |
| Synonyms
|
- Protein FAM42A
|
| Gene Name
| EFTUD1 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in GTPase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Function |
| nucleotide binding |
| catalytic activity |
| hydrolase activity |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| gtpase activity |
| nucleoside-triphosphatase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| pyrophosphatase activity |
| purine nucleotide binding |
| binding |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 15q25.2 |
| SNPs
| EFTUD1 |
| Gene Sequence
|
>3363 bp
ATGGTGCTCAACAGTTTGGATAAGATGATTCAACTCCAGAAAAACACTGCCAACATCAGG
AATATTTGTGTTTTGGCTCATGTTGACCATGGAAAAACTACTCTGGCTGACTGTCTTATA
TCTAGCAATGGAATCATCTCCAGCCGCCTAGCAGGCAAGTTAAGGTACATGGACAGCAGA
GAAGATGAACAGATCCGAGGGATCACTATGAAATCCAGTGCCATTTCCCTACATTATGCA
ACAGGTAATGAGGAGTACCTGATCAATCTGATAGACTCTCCAGGACACGTGGACTTTTCC
TCAGAAGTATCAACCGCTGTTCGCATTTGTGATGGATGCATCATTGTGGTAGATGCTGTG
GAAGGAGTCTGTCCACAGACACAGGCAGTTCTGCGACAAGCTTGGCTTGAAAACATCCGT
CCGGTTTTAGTGATTAATAAGATTGATCGCTTGATAGTGGAACTGAAATTCACCCCACAA
GAGGCCTATTCTCACCTCAAGAATATTTTAGAACAGATTAATGCGCTCACAGGGACTCTT
TTTACTTCTAAAGTCCTAGAAGAAAGAGCAGAGAGGGAGACTGAATCCCAAGTGAATCCA
AATTCTGAACAAGGAGAGCAAGTATATGACTGGAGCACTGGCTTGGAGGACACAGATGAT
TCTCACCTTTACTTCTCTCCAGAACAGGGAAATGTGGTGTTTACCAGTGCAATAGATGGG
TGGGGCTTTGGAATTGAGCACTTCGCCAGAATCTACAGTCAAAAAATTGGCATCAAAAAG
GAAGTTCTTATGAAAACCTTGTGGGGAGATTACTATATAAATATGAAGGCTAAAAAGATC
ATGAAGGGTGATCAGGCCAAAGGAAAGAAACCTTTATTTGTACAGTTGATCCTGGAAAAT
ATATGGAGTTTGTATGATGCTGTTTTGAAAAAGGACAAAGACAAAATTGATAAAATAGTG
ACTTCTTTAGGATTAAAAATTGGAGCCCGGGAGGCACGACATTCAGACCCTAAAGTTCAG
ATCAACGCCATTTGCAGTCAGTGGCTACCCATATCCCATGCTGTTCTTGCTATGGTGTGT
CAGAAACTTCCTAGTCCCCTTGATATTACAGCTGAGAGAGTGGAGAGACTGATGTGCACA
GGATCACAAACTTTTGACTCTTTTCCACCAGAAACTCAAGCACTGAAAGCAGCTTTTATG
AAATGTGGAAGTGAGGACACTGCTCCAGTTATTATATTTGTTTCCAAAATGTTTGCAGTT
GATGCTAAGGCCTTGCCTCAGAATAAGCCAAGGCCTCTCACTCAAGAAGAAATTGCTCAG
AGACGTGAGCGTGCAAGACAAAGGCATGCAGAGAAGCTTGCAGCAGCACAGGGACAGGCA
CCCTTGGAGCCCACCCAAGATGGGAGTGCCATTGAAACATGTCCAAAAGGAGAGGAGCCA
AGAGGTGACGAGCAACAGGTGGAAAGTATGACCCCTAAACCTGTGCTCCAGGAAGAAAAC
AACCAAGAGTCTTTTATTGCATTTGCTCGGGTGTTCAGTGGTGTGGCTCGAAGAGGAAAG
AAAATTTTTGTCTTGGGGCCCAAATACAGTCCTCTTGAGTTTTTACGAAGGGTACCATTA
GGCTTCTCAGCTCCACCAGATGGCCTCCCCCAAGTCCCCCACATGGCATACTGTGCTCTG
GAAAACCTGTATCTTCTGATGGGAAGGGAACTGGAATATCTAGAGGAGGTACCTCCAGGA
AATGTGCTAGGAATAGGAGGCCTTCAAGATTTTGTGCTGAAATCTGCAACACTGTGTAGC
CTGCCATCCTGCCCACCATTTATACCACTCAACTTCGAAGCCACTCCTATTGTGAGAGTT
GCTGTTGAACCAAAACATCCAAGTGAAATGCCTCAGCTCGTAAAAGGAATGAAACTGTTA
AACCAGGCTGATCCCTGTGTCCAGATTTTAATTCAGGAAACGGGAGAGCACGTTTTAGTC
ACAGCAGGAGAAGTCCACCTTCAGCGATGCCTGGATGACTTAAAAGAAAGGTTTGCAAAG
ATTCATATCAGTGTATCTGAACCTATTATTCCATTCAGAGAAACAATCACAAAACCCCCA
AAAGTTGACATGGTCAATGAAGAAATAGGCAAACAGCAAAAAGTTGCAGTCATACACCAA
ATGAAAGAAGATCAAAGCAAAATCCCTGAAGGAATCCAAGTTGACTCTGACGGGCTAATC
ACCATAACAACTCCCAATAAACTTGCCACGCTCAGTGTTCGAGCCATGCCCCTTCCAGAA
GAAGTCACCCAGATTCTGGAAGAAAATAGTGATTTGATTCGTTCTATGGAGCAGTTGACA
TCCTCTTTGAATGAGGGTGAAAATACTCACATGATTCATCAGAAGACCCAAGAGAAAATT
TGGGAATTCAAAGGAAAACTGGAGCAACACCTAACAGGGAGAAGATGGAGGAACATTGTT
GACCAAATCTGGTCATTTGGCCCAAGAAAATGTGGGCCCAACATACTAGTCAATAAAAGT
GAAGATTTTCAGAACTCAGTATGGACAGGTCCAGCTGACAAAGCTTCAAAAGAAGCCAGT
AGATACCGAGATTTGGGCAATAGCATTGTGAGTGGCTTCCAACTAGCAACCCTCTCTGGC
CCCATGTGTGAGGAGCCTCTCATGGGTGTCTGTTTTGTTCTGGAAAAATGGGACCTAAGT
AAATTTGAGGAACAAGGAGCAAGTGATCTGGCAAAAGAGGGACAGGAGGAAAATGAAACC
TGTTCTGGTGGAAATGAAAACCAAGAGCTACAAGATGGCTGCTCTGAGGCCTTTGAGAAG
AGGACATCACAGAAAGGAGAATCTCCACTCACTGACTGCTATGGACCTTTCTCAGGACAG
CTAATTGCCACCATGAAAGAAGCATGTCGCTATGCACTGCAAGTGAAACCTCAGCGCCTG
ATGGCAGCTATGTACACATGTGACATCATGGCCACTGGTGATGTTCTCGGTCGAGTCTAT
GCTGTCTTGTCAAAGAGAGAAGGTCGGGTACTTCAAGAAGAAATGAAAGAAGGGACAGAC
ATGTTCATCATCAAGGCTGTGCTGCCTGTTGCTGAAAGCTTTGGTTTTGCTGATGAAATC
AGGAAGAGGACAAGTGGCCTGGCCAGCCCACAACTAGTATTCAGCCATTGGGAGATCATT
CCCAGTGACCCCTTCTGGGTGCCAACTACTGAGGAGGAATACTTGCACTTTGGGGAGAAG
GCTGACTCTGAGAACCAAGCCCGGAAGTACATGAACGCAGTACGAAAGCGGAAGGGGCTT
TATGTGGAAGAAAAGATTGTGGAGCATGCAGAAAAGCAGAGGACACTCAGCAAAAATAAG
TAG
|
| Protein Properties |
| Number of Residues
| 1120 |
| Molecular Weight
| 125428.7 |
| Theoretical pI
| 5.72 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Elongation factor Tu GTP-binding domain-containing protein 1
MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSR
EDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAV
EGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTL
FTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDG
WGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGKKPLFVQLILEN
IWSLYDAVLKKDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVC
QKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAV
DAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAAQGQAPLEPTQDGSAIETCPKGEEP
RGDEQQVESMTPKPVLQEENNQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPL
GFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCS
LPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLV
TAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQ
MKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLT
SSLNEGENTHMIHQKTQEKIWEFKGKLEQHLTGRRWRNIVDQIWSFGPRKCGPNILVNKS
EDFQNSVWTGPADKASKEASRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLS
KFEEQGASDLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQ
LIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTD
MFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEK
ADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK
|
| External Links |
| GenBank ID Protein
| 94966754 |
| UniProtKB/Swiss-Prot ID
| Q7Z2Z2 |
| UniProtKB/Swiss-Prot Entry Name
| ETUD1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_024580.5 |
| GeneCard ID
| EFTUD1 |
| GenAtlas ID
| EFTUD1 |
| HGNC ID
| HGNC:25789 |
| References |
| General References
| Not Available |