Cannabis Compound Database: Showing Protein Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (CDBP03596)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03596

Secondary Accession Numbers

Not Available

Name

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

Description

Not Available

Synonyms

Eukaryotic peptide chain release factor subunit 3a
G1 to S phase transition protein 1 homolog
eRF3a

Gene Name

GSPT1

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTPase activity

Specific Function

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth

GO Classification

Function
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding

Cellular Location

Cytoplasmic

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

16p13.1

SNPs

GSPT1

Gene Sequence

>1500 bp
ATGGAACTTTCAGAACCTATTGTAGAAAATGGAGAGACAGAAATGTCTCCAGAAGAATCA
TGGGAGCACAAAGAAGAAATAAGTGAAGCAGAGCCAGGGGGTGGTTCCTTGGGAGATGGA
AGGCCGCCAGAGGAAAGTGCCCATGAAATGATGGAGGAGGAAGAGGAAATCCCAAAACCT
AAGTCTGTGGTTGCACCGCCAGGTGCTCCTAAGAAAGAGCATGTAAATGTAGTATTCATT
GGGCACGTAGATGCTGGCAAGTCAACCATTGGAGGACAAATAATGTATTTGACTGGAATG
GTTGACAAAAGGACGCTTGAAAAGTATGAAAGAGAAGCTAAAGAGAAAAACAGAGAAACT
TGGTACTTGTCTTGGGCCTTAGACACAAATCAGGAAGAACGAGACAAGGGTAAAACAGTA
GAAGTGGGTCGTGCCTATTTTGAAACCGAAAAGAAGCATTTCACAATTCTAGATGCCCCT
GGCCACAAGAGTTTTGTCCCAAATATGATTGGTGGTGCCTCTCAAGCTGATTTGGCTGTG
CTGGTAATCTCAGCCAGGAAAGGAGAGTTTGAAACTGGATTTGAAAAAGGAGGACAGACA
AGAGAACATGCAATGTTGGCAAAGACAGCAGGTGTAAAACACCTAATTGTGCTAATTAAT
AAGATGGATGATCCAACAGTAAATTGGAGCAATGAGAGATATGAAGAATGTAAGGAGAAA
CTAGTGCCATTTTTGAAAAAAGTTGGCTTCAATCCCAAAAAGGACATTCACTTTATGCCC
TGCTCAGGACTTACTGGAGCAAATCTCAAAGAGCAGTCGGATTTCTGTCCTTGGTACATT
GGATTACCGTTTATTCCATATCTGGATAATTTGCCGAACTTCAATAGATCAGTTGATGGA
CCAATCAGGCTGCCAATTGTGGATAAGTACAAGGATATGGGCACTGTGGTCCTGGGAAAG
CTGGAATCAGGATCTATTTGTAAAGGCCAGCAGCTTGTGATGATGCCAAACAAGCACAAC
GTGGAAGTTCTTGGAATACTTTCCGATGATGTAGAGACTGATACCGTAGCCCCAGGTGAA
AACCTCAAAATCAGACTGAAAGGAATTGAAGAAGAGGAGATTCTTCCAGGGTTTATACTT
TGTGATCCTAATAATCTTTGTCATTCTGGACGCACATTTGATGCCCAGATAGTGATTATA
GAGCACAAATCCATCATCTGCCCAGGCTATAATGCGGTGCTGCATATTCATACCTGTATT
GAGGAGGTGGAAATAACAGCCTTAATCTGCTTGGTAGACAAAAAATCAGGAGAAAAAAGT
AAGACCCGACCCCGTTTTGTGAAACAAGATCAAGTATGCATTGCTCGCTTAAGGACAGCA
GGAACCATCTGCCTTGAGACCTTTAAAGACTTCCCTCAGATGGGTCGTTTCACCTTAAGA
GATGAGGGTAAGACCATTGCAATTGGAAAAGTTCTGAAACTGGTTCCAGAGAAAGACTAA

Protein Properties

Number of Residues

499

Molecular Weight

55755.6

Theoretical pI

5.34

Pfam Domain Function

GTP_EFTU (PF00009 )
GTP_EFTU_D2 (PF03144 )
GTP_EFTU_D3 (PF03143 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
MELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKP
KSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRET
WYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAV
LVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEK
LVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDG
PIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGE
NLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCI
EEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLR
DEGKTIAIGKVLKLVPEKD

External Links

GenBank ID Protein

31921

UniProtKB/Swiss-Prot ID

P15170

UniProtKB/Swiss-Prot Entry Name

ERF3A_HUMAN

PDB IDs

Not Available

GenBank Gene ID

X17644

GeneCard ID