| Identification |
|---|
| HMDB Protein ID
| CDBP03590 |
| Secondary Accession Numbers
| Not Available |
| Name
| Translation initiation factor eIF-2B subunit delta |
| Description
| Not Available |
| Synonyms
|
- eIF-2B GDP-GTP exchange factor subunit delta
|
| Gene Name
| EIF2B4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cellular metabolic process |
| Specific Function
| Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP |
| GO Classification
|
| Process |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2p23.3 |
| SNPs
| EIF2B4 |
| Gene Sequence
|
>1572 bp
ATGGCTGCTGTGGCCGTGGCTGTTCGCGAGGACTCGGGATCCGGGATGAAGGCGGAGCTT
CCCCCTGGGCCTGGGGCAGTGGGGAGGGAAATGACCAAAGAAGAAAAGCTGCAGCTTCGG
AAGGAAAAGAAACAGCAGAAGAAGAAACGGAAGGAAGAAAAGGGGGCAGAACCAGAGACT
GGCTCTGCTGTATCTGCAGCCCAATGTCAAGTAGGCCCAACCAGAGAACTGCCAGAATCG
GGCATTCAGTTGGGCACTCCTCGGGAGAAAGTTCCAGCTGGTCGGAGTAAGGCCGAACTT
CGGGCTGAGCGTCGAGCCAAGCAGGAGGCCGAGCGGGCCCTGAAACAGGCAAGAAAAGGG
GAACAAGGAGGACCACCTCCTAAGGCCAGCCCCAGCACAGCTGGAGAAACCCCCTCAGGA
GTGAAGCGTCTCCCTGAGTACCCTCAGGTTGATGACCTACTTCTGAGAAGGCTTGTTAAA
AAACCAGAGCGTCAACAGGTTCCTACACGAAAGGATTATGGATCCAAAGTCAGTCTCTTC
TCTCACCTACCCCAGTACAGCAGACAAAACTCTCTGACCCAGTTTATGAGCATCCCATCC
TCTGTGATCCACCCAGCCATGGTGCGACTCGGCCTGCAGTACTCCCAGGGCCTGGTCAGT
GGCTCCAATGCCCGGTGTATTGCCCTGCTTCGTGCCTTGCAGCAGGTGATTCAGGATTAC
ACAACACCGCCTAATGAAGAACTCTCCAGGGATCTAGTGAATAAACTAAAACCCTACATG
AGCTTCCTGACTCAGTGCCGTCCCCTGTCAGCGAGCATGCACAACGCCATCAAGTTCCTT
AACAAGGAAATCACCAGTGTGGGCAGTTCCAAGCGGGAAGAGGAGGCCAAGTCAGAACTT
CGAGCAGCCATTGATCGGTATGTGCAAGAGAAGATTGTGCTAGCAGCTCAGGCAATTTCA
CGCTTTTCTTACCAGAAGATCAGTAATGGAGATGTGATCCTGGTATATGGATGCTCATCT
CTGGTATCACGAATTCTTCAGGAGGCTTGGACAGAGGGCCGGCGGTTTCGGGTGGTAGTG
GTGGACAGCCGGCCATGGCTGGAAGGAAGGCACACACTACGTTCTCTAGTCCATGCTGGT
GTCCCAGCCTCCTACCTGCTGATTCCTGCAGCCTCCTATGTGCTCCCAGAGGTTTCCAAG
GTGCTATTGGGAGCTCATGCACTCTTGGCCAACGGGTCTGTGATGTCACGGGTAGGGACA
GCACAGTTAGCCCTGGTGGCTCGAGCCCATAATGTACCAGTGCTGGTTTGCTGTGAAACA
TACAAGTTCTGTGAGCGTGTGCAGACTGATGCCTTTGTCTCTAATGAGCTAGATGACCCT
GATGATCTGCAATGTAAGCGGGGAGAACATGTTGCGCTGGCTAACTGGCAGAACCACGCA
CTCCTACGGTTGTTGAATCTAGTCTATGATGTGACTCCCCCAGAGCTTGTGGATCTGGTG
ATCACGGAGCTGGGGATGATCCCTTGCAGTTCTGTACCTGTTGTTCTACGAGTCAAGAGC
AGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 523 |
| Molecular Weight
| 57556.7 |
| Theoretical pI
| 9.87 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Translation initiation factor eIF-2B subunit delta
MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 6563202 |
| UniProtKB/Swiss-Prot ID
| Q9UI10 |
| UniProtKB/Swiss-Prot Entry Name
| EI2BD_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF112207 |
| GeneCard ID
| EIF2B4 |
| GenAtlas ID
| EIF2B4 |
| HGNC ID
| HGNC:3260 |
| References |
|---|
| General References
| Not Available |