| Identification |
|---|
| HMDB Protein ID
| CDBP03588 |
| Secondary Accession Numbers
| Not Available |
| Name
| Translation initiation factor eIF-2B subunit alpha |
| Description
| Not Available |
| Synonyms
|
- eIF-2B GDP-GTP exchange factor subunit alpha
|
| Gene Name
| EIF2B1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cellular metabolic process |
| Specific Function
| Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP |
| GO Classification
|
| Process |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12q24.31 |
| SNPs
| EIF2B1 |
| Gene Sequence
|
>918 bp
ATGGACGACAAGGAGTTAATTGAATACTTTAAGTCTCAGATGAAAGAAGATCCTGACATG
GCCTCAGCAGTGGCTGCCATCCGGACGTTGCTGGAGTTCTTGAAGAGAGATAAAGGGGAG
ACAATCCAGGGTCTGAGGGCGAATCTCACCAGTGCCATAGAAACCCTGTGTGGTGTGGAC
TCCTCTGTGGCAGTGTCCTCTGGCGGGGAGCTCTTCCTCCGCTTCATCAGTCTTGCCTCC
CTGGAATACTCCGATTACTCCAAATGTAAAAAGATCATGATTGAGCGGGGAGAACTTTTT
CTCAGGAGAATATCACTGTCAAGAAACAAAATTGCAGATCTGTGCCATACTTTCATCAAA
GATGGAGCGACAATATTGACTCACGCCTACTCCAGAGTGGTCCTGAGAGTCCTGGAAGCA
GCCGTGGCGGCCAAGAAGCGATTTAGTGTATACGTCACAGAGTCACAGCCTGATTTGTCA
GGTAAGAAAATGGCCAAAGCCCTCTGCCACCTCAACGTCCCTGTCACTGTGGTGCTAGAT
GCTGCTGTCGGCTACATCATGGAGAAAGCAGATCTTGTCATAGTTGGTGCTGAAGGAGTT
GTTGAAAACGGAGGAATTATTAACAAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAA
GCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGTTTCAAGTTTGTCCGGCTCTTTCCA
CTAAACCAGCAAGACGTCCCAGATAAGTTTAAGTATAAGGCAGACACTCTCAAGGTCGCG
CAGACTGGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTA
ATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACACCCTCAGCAGTCAGCGATGAGCTC
ATCAAGCTCTATCTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 305 |
| Molecular Weight
| 33711.8 |
| Theoretical pI
| 7.4 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Translation initiation factor eIF-2B subunit alpha
MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVD
SSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIK
DGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLD
AAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFP
LNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDEL
IKLYL
|
| External Links |
|---|
| GenBank ID Protein
| 4503503 |
| UniProtKB/Swiss-Prot ID
| Q14232 |
| UniProtKB/Swiss-Prot Entry Name
| EI2BA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001414.3 |
| GeneCard ID
| EIF2B1 |
| GenAtlas ID
| EIF2B1 |
| HGNC ID
| HGNC:3257 |
| References |
|---|
| General References
| Not Available |