| Identification |
| HMDB Protein ID
| CDBP03561 |
| Secondary Accession Numbers
| Not Available |
| Name
| GTP-binding protein Di-Ras1 |
| Description
| Not Available |
| Synonyms
|
- Distinct subgroup of the Ras family member 1
- Ras-related inhibitor of cell growth
- Rig
- Small GTP-binding tumor suppressor 1
|
| Gene Name
| DIRAS1 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in GTP binding |
| Specific Function
| Displays low GTPase activity and exist predominantly in the GTP-bound form |
| GO Classification
|
| Component |
| membrane |
| cell part |
| intracellular |
| Function |
| catalytic activity |
| hydrolase activity |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| gtpase activity |
| nucleoside-triphosphatase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| pyrophosphatase activity |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
| small gtpase mediated signal transduction |
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13.3 |
| SNPs
| DIRAS1 |
| Gene Sequence
|
>597 bp
ATGCCGGAACAGAGTAACGATTACCGCGTGGTGGTGTTCGGGGCGGGCGGCGTGGGCAAG
AGCTCGCTGGTGCTGCGCTTCGTGAAGGGCACGTTCCGCGACACCTACATCCCCACCATC
GAGGACACCTACCGGCAGGTGATCAGCTGCGACAAGAGCGTGTGCACGCTGCAGATCACA
GACACCACCGGCAGCCACCAGTTCCCGGCCATGCAGCGCCTGTCCATCTCCAAGGGCCAC
GCCTTCATCCTGGTGTTCTCCGTCACCAGCAAGCAGTCGCTGGAGGAGCTGGGGCCCATC
TACAAGCTCATCGTGCAGATCAAGGGCAGCGTGGAGGACATCCCCGTGATGCTCGTGGGC
AACAAGTGCGATGAGACGCAGCGGGAGGTGGACACGCGCGAGGCGCAGGCGGTGGCCCAG
GAGTGGAAGTGCGCTTTCATGGAGACCTCGGCCAAGATGAACTACAACGTCAAGGAGCTC
TTCCAGGAGCTGCTGACGCTGGAGACGCGCCGGAACATGAGCCTCAACATCGACGGCAAG
CGCTCCGGGAAGCAGAAGAGGACAGACCGCGTCAAGGGCAAATGCACCCTCATGTGA
|
| Protein Properties |
| Number of Residues
| 198 |
| Molecular Weight
| 22328.6 |
| Theoretical pI
| 8.97 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>GTP-binding protein Di-Ras1
MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQIT
DTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVG
NKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGK
RSGKQKRTDRVKGKCTLM
|
| External Links |
| GenBank ID Protein
| 21624248 |
| UniProtKB/Swiss-Prot ID
| O95057 |
| UniProtKB/Swiss-Prot Entry Name
| DIRA1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB076888 |
| GeneCard ID
| DIRAS1 |
| GenAtlas ID
| DIRAS1 |
| HGNC ID
| HGNC:19127 |
| References |
| General References
| Not Available |