| Identification |
|---|
| HMDB Protein ID
| CDBP03539 |
| Secondary Accession Numbers
| Not Available |
| Name
| CDC42 small effector protein 2 |
| Description
| Not Available |
| Synonyms
|
- Small effector of CDC42 protein 2
|
| Gene Name
| CDC42SE2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasm
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31.1 |
| SNPs
| CDC42SE2 |
| Gene Sequence
|
>255 bp
ATGAGTGAATTCTGGTTGTGTTTCAACTGCTGTATTGCAGAACAGCCTCAGCCTAAAAGG
CGACGGCGGATTGACAGAAGTATGATTGGAGAGCCCACAAACTTTGTGCATACAGCTCAT
GTTGGATCAGGAGACCTGTTCAGTGGAATGAATTCAGTTAGCTCCATTCAGAACCAAATG
CAGTCCAAGGGAGGTTATGGAGGTGGAATGCCTGCCAATGTCCAGATGCAGCTCGTGGAT
ACGAAGGCGGGATAG
|
| Protein Properties |
|---|
| Number of Residues
| 84 |
| Molecular Weight
| 9223.5 |
| Theoretical pI
| 8.52 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>CDC42 small effector protein 2
MSEFWLCFNCCIAEQPQPKRRRRIDRSMIGEPTNFVHTAHVGSGDLFSGMNSVSSIQNQM
QSKGGYGGGMPANVQMQLVDTKAG
|
| External Links |
|---|
| GenBank ID Protein
| 9453926 |
| UniProtKB/Swiss-Prot ID
| Q9NRR3 |
| UniProtKB/Swiss-Prot Entry Name
| C42S2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF189692 |
| GeneCard ID
| CDC42SE2 |
| GenAtlas ID
| CDC42SE2 |
| HGNC ID
| HGNC:18547 |
| References |
|---|
| General References
| Not Available |