| Identification |
|---|
| HMDB Protein ID
| CDBP03534 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cdc42 effector protein 3 |
| Description
| Not Available |
| Synonyms
|
- Binder of Rho GTPases 2
- MSE55-related Cdc42-binding protein
|
| Gene Name
| CDC42EP3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cytoskeletal regulatory protein binding |
| Specific Function
| Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Endomembrane system
- Peripheral membrane protein
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2p21 |
| SNPs
| CDC42EP3 |
| Gene Sequence
|
>765 bp
ATGCCAGCCAAGACCCCAATTTACCTGAAAGCAGCCAATAACAAGAAAGGAAAGAAATTT
AAACTGAGGGACATTCTGTCTCCTGATATGATCAGTCCCCCGCTTGGAGACTTTCGCCAC
ACCATCCACATTGGCAAAGAGGGCCAGCACGATGTCTTTGGAGATATTTCCTTTCTTCAA
GGGAACTACGAGCTTTTACCTGGAAACCAGGAGAAAGCACACCTGGGCCAGTTCCCTGGG
CATAATGAGTTCTTCCGGGCCAACAGCACCTCGGACTCTGTGTTCACAGAAACGCCCTCC
CCGGTGCTCAAAAATGCCATCTCCCTCCCGACCATTGGAGGATCCCAAGCTCTCATGTTG
CCCTTATTGTCACCAGTGACATTTAATTCCAAACAGGAGTCCTTCGGGCCAGCAAAGCTG
CCCAGGCTTAGCTGCGAGCCCGTCATGGAGGAAAAAGCTCAGGAGAAAAGCAGTCTGTTG
GAGAATGGGACAGTCCACCAGGGAGACACCTCGTGGGGCTCCAGCGGTTCTGCATCTCAG
TCCAGCCAAGGCAGAGACAGCCACTCCTCCAGCCTGTCCGAACAGTACCCCGACTGGCCA
GCCGAGGACATGTTTGACCATCCCACCCCATGCGAGCTCATCAAGGGAAAGACTAAGTCA
GAGGAGTCCCTCTCTGACCTTACAGGTTCCCTCCTCTCCCTGCAGCTTGATCTTGGGCCC
TCACTTTTGGATGAGGTGCTGAATGTAATGGATAAAAATAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 254 |
| Molecular Weight
| 27677.8 |
| Theoretical pI
| 5.58 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cdc42 effector protein 3
MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQ
GNYELLPGNQEKAHLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQALML
PLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSASQ
SSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDLGP
SLLDEVLNVMDKNK
|
| External Links |
|---|
| GenBank ID Protein
| 62702145 |
| UniProtKB/Swiss-Prot ID
| Q9UKI2 |
| UniProtKB/Swiss-Prot Entry Name
| BORG2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC006369 |
| GeneCard ID
| CDC42EP3 |
| GenAtlas ID
| CDC42EP3 |
| HGNC ID
| HGNC:16943 |
| References |
|---|
| General References
| Not Available |