| Identification |
|---|
| HMDB Protein ID
| CDBP03533 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cdc42 effector protein 2 |
| Description
| Not Available |
| Synonyms
|
- Binder of Rho GTPases 1
|
| Gene Name
| CDC42EP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP-Rho binding |
| Specific Function
| Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Endomembrane system
- Peripheral membrane protein
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q13 |
| SNPs
| CDC42EP2 |
| Gene Sequence
|
>633 bp
ATGTCCACCAAGGTGCCCATCTATCTGAAGCGTGGCAGTCGCAAGGGCAAGAAGGAGAAG
CTTCGGGACCTGCTGTCCTCGGACATGATCAGCCCACCGCTGGGGGACTTCCGCCACACC
ATTCATATTGGCAGTGGCGGCGGCAGTGACATGTTTGGCGACATCTCCTTCCTGCAGGGC
AAGTTCCACCTCCTGCCGGGGACCATGGTGGAGGGGCCTGAAGAAGATGGCACCTTCGAC
CTCCCCTTCCAGTTCACCCGCACCGCCACCGTGTGTGGGCGGGAGCTCCCGGACGGCCCA
TCCCCTCTGCTCAAGAACGCCATCTCCCTCCCGGTTATCGGTGGACCCCAGGCTCTCACC
CTGCCCACAGCCCAGGCTCCACCCAAGCCCCCTCGCCTGCACCTGGAGACCCCTCAGCCT
TCCCCACAGGAGGGAGGGAGTGTGGACATCTGGAGGATTCCAGAGACTGGCTCCCCCAAC
AGTGGACTGACCCCGGAGTCAGGGGCCGAGGAGCCCTTCCTGTCCAATGCCAGCTCCCTG
CTGTCCCTGCACGTGGACCTGGGGCCTTCCATCCTGGATGATGTCCTGCAGATCATGGAT
CAGGACCTGGACAGCATGCAGATCCCCACATAG
|
| Protein Properties |
|---|
| Number of Residues
| 210 |
| Molecular Weight
| 22483.3 |
| Theoretical pI
| 4.73 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cdc42 effector protein 2
MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQG
KFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALT
LPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSL
LSLHVDLGPSILDDVLQIMDQDLDSMQIPT
|
| External Links |
|---|
| GenBank ID Protein
| 2529711 |
| UniProtKB/Swiss-Prot ID
| O14613 |
| UniProtKB/Swiss-Prot Entry Name
| BORG1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF001436 |
| GeneCard ID
| CDC42EP2 |
| GenAtlas ID
| CDC42EP2 |
| HGNC ID
| HGNC:16263 |
| References |
|---|
| General References
| Not Available |