| Identification |
|---|
| HMDB Protein ID
| CDBP03516 |
| Secondary Accession Numbers
| Not Available |
| Name
| ADP-ribosylation factor 4 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| ARF4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| Process |
| small gtpase mediated signal transduction |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
|
| Cellular Location
|
- Golgi apparatus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p21.2-p21.1 |
| SNPs
| ARF4 |
| Gene Sequence
|
>543 bp
ATGGGCCTCACTATCTCCTCCCTCTTCTCCCGACTATTTGGCAAGAAGCAGATGCGCATT
TTGATGGTTGGATTGGATGCTGCTGGCAAGACAACCATTCTGTATAAACTGAAGTTAGGG
GAGATAGTCACCACCATTCCTACCATTGGTTTTAATGTGGAAACAGTAGAATATAAGAAC
ATTTGTTTCACAGTATGGGATGTTGGTGGTCAAGATAGAATTAGGCCTCTCTGGAAGCAT
TACTTCCAGAATACCCAGGGTCTTATTTTTGTGGTAGATAGCAACGATCGTGAAAGAATT
CAGGAAGTAGCAGATGAGCTGCAGAAAATGCTTCTGGTAGATGAATTGAGAGATGCAGTG
CTGCTACTTTTTGCAAACAAACAGGATTTGCCAAATGCTATGGCCATCAGTGAAATGACA
GATAAACTAGGGCTTCAGTCTCTTCGTAACAGAACATGGTATGTTCAAGCCACTTGTGCA
ACACAAGGAACTGGTCTGTATGAAGGACTTGACTGGCTGTCAAATGAGCTTTCAAAACGT
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 180 |
| Molecular Weight
| 20510.6 |
| Theoretical pI
| 7.25 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>ADP-ribosylation factor 4
MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV
LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR
|
| External Links |
|---|
| GenBank ID Protein
| 178985 |
| UniProtKB/Swiss-Prot ID
| P18085 |
| UniProtKB/Swiss-Prot Entry Name
| ARF4_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M36341 |
| GeneCard ID
| ARF4 |
| GenAtlas ID
| ARF4 |
| HGNC ID
| HGNC:655 |
| References |
|---|
| General References
| Not Available |