Showing Protein NADPH-dependent diflavin oxidoreductase 1 (CDBP03492)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 4 compounds
Identification
HMDB Protein ID CDBP03492
Secondary Accession Numbers Not Available
Name NADPH-dependent diflavin oxidoreductase 1
Description Not Available
Synonyms
  1. NADPH-dependent FMN and FAD-containing oxidoreductase
  2. Novel reductase 1
Gene Name NDOR1
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity
Specific Function Oxidoreductase that catalyzes the NADP-dependent reduction of cytochrome c and one-electron acceptors, such as doxorubicin, potassium ferricyanide and menadione (in vitro)
GO Classification
Function
catalytic activity
transition metal ion binding
iron ion binding
fmn binding
oxidoreductase activity
ion binding
cation binding
metal ion binding
binding
nucleotide binding
Process
metabolic process
oxidation reduction
Cellular Location
  1. Cytoplasm
  2. perinuclear region
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9q34.3
SNPs NDOR1
Gene Sequence 
>1794 bp
ATGCCGAGCCCGCAGCTTCTGGTGCTCTTCGGCAGCCAGACAGGCACGGCTCAGGATGTG
TCGGAGAGACTGGGTCGCGAGGCCCGGCGCCGGCGGCTTGGCTGCCGGGTGCAGGCCCTG
GACTCCTACCCGGTGGTGAATCTGATTAACGAGCCCCTGGTGATATTTGTTTGTGCAACT
ACAGGCCAAGGAGACCCCCCTGACAACATGAAGAACTTCTGGAGGTTTATATTCCGGAAG
AACCTGCCCTCCACTGCCCTCTGTCAGATGGACTTTGCCGTCCTGGGCCTCGGGGACTCC
TCATACGCCAAGTTCAACTTCGTGGCCAAGAAGCTGCACCGACGGCTACTGCAGCTTGGG
GGCAGCGCCCTCCTGCCCGTGTGCCTGGGCGATGACCAGCATGAGCTGGGGCCCGACGCT
GCTGTGGACCCCTGGCTGCGAGACTTGTGGGACAGGGTTCTGGGGCTGTACCCGCCGCCT
CCGGGCCTCACTGAGATCCCTCCCGGAGTCCCCCTGCCCTCCAAGTTCACCCTGCTGTTC
CTCCAAGAGGCACCCAGCACGGGCTCTGAGGGGCAGCGGGTAGCTCACCCCGGCTCTCAG
GAGCCCCCGTCAGAGTCGAAGCCCTTCCTAGCACCCATGATCTCCAACCAGAGAGTCACC
GGCCCCTCCCACTTCCAGGACGTTCGGCTGATTGAGTTTGACATCTTGGGCTCTGGCATC
AGCTTTGCTGCTGGTGATGTGGTGCTGATTCAGCCCTCCAACTCGGCTGCCCATGTCCAG
CGGTTCTGCCAGGTGCTGGGCCTGGACCCTGACCAGCTCTTCATGCTGCAGCCGCGGGAG
CCAGATGTCTCCTCCCCCACGAGGCTGCCCCAGCCCTGCTCCATGCGGCACCTCGTGTCC
CACTACCTGGACATCGCCAGCGTGCCTCGCCGCTCCTTCTTCGAACTCCTGGCCTGTCTA
TCCCTCCATGAGCTGGAGCGGGAGAAGCTGCTGGAGTTCAGTTCTGCCCAAGGCCAGGAG
GAGCTCTTTGAATACTGCAACCGGCCCCGCAGGACCATCCTGGAGGTGCTCTGTGACTTC
CCGCACACAGCTGCCGCCATCCCTCCCGACTACCTGTTGGACCTCATCCCCGTTATCCGG
CCGAGGGCCTTCTCCATCGCCTCCTCGCTGCTGACTCACCCCTCACGGCTGCAGATCCTC
GTGGCTGTAGTGCAGTTCCAGACTCGCCTCAAGGAGCCCCGCCGGGGCCTCTGCTCCTCC
TGGCTGGCATCCCTGGACCCTGGGCAAGGACCTGTCCGGGTGCCCCTCTGGGTGCGGCCT
GGGAGTCTGGCCTTCCCAGAGACACCAGACACACCTGTGATCATGGTGGGGCCTGGCACT
GGGGTAGCCCCCTTCCGAGCAGCCATCCAGGAGCGTGTGGCCCAGGGCCAGACTGGAAAC
TTCTTGTTTTTTGGCTGCCGCTGGCGGGACCAAGACTTCTACTGGGAGGCTGAGTGGCAG
GAGCTGGAGAAGCGGGACTGTCTGACCCTCATCCCTGCCTTCTCCCGGGAACAGGAGCAG
AAAGTATATGTGCAGCACCGGCTCCGGGAGCTGGGGTCGCTTGTGTGGGAACTGCTGGAC
CGCCAGGGTGCATACTTCTACCTGGCAGGCAACGCCAAGTCCATGCCAGCGGACGTCTCG
GAAGCCCTGATGTCCATCTTCCAGGAGGAGGGTGGACTCTGCAGCCCGGACGCAGCCGCG
TATCTAGCCAGGCTCCAGCAGACACGGCGCTTCCAGACAGAGACGTGGGCCTGA
Protein Properties
Number of Residues 597
Molecular Weight 66761.9
Theoretical pI 6.3
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>NADPH-dependent diflavin oxidoreductase 1
MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT
TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG
GSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLF
LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI
SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS
HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF
PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS
WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN
FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD
RQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA
GenBank ID Protein 6694369
UniProtKB/Swiss-Prot ID Q9UHB4
UniProtKB/Swiss-Prot Entry Name NDOR1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF199509
GeneCard ID NDOR1
GenAtlas ID NDOR1
HGNC ID HGNC:29838
References
General References Not Available