| Identification |
|---|
| HMDB Protein ID
| CDBP03471 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein SCO2 homolog, mitochondrial |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| SCO2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in copper ion binding |
| Specific Function
| Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2) |
| GO Classification
|
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| copper ion binding |
| Process |
| homeostatic process |
| cellular component organization or biogenesis |
| chemical homeostasis |
| biological regulation |
| ion homeostasis |
| cellular component organization |
| cellular ion homeostasis |
| cellular component assembly |
| cellular cation homeostasis |
| macromolecular complex assembly |
| cellular di-, tri-valent inorganic cation homeostasis |
| cellular protein complex assembly |
| respiratory chain complex iv assembly |
| cellular copper ion homeostasis |
| protein complex assembly |
| cellular homeostasis |
| cell redox homeostasis |
| ion transport |
| copper ion transport |
| cation transport |
| metal ion transport |
| establishment of localization |
| transition metal ion transport |
| cellular process |
| regulation of biological quality |
| transport |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22q13.33 |
| SNPs
| SCO2 |
| Gene Sequence
|
>801 bp
ATGCTGCTGCTGACTCGGAGCCCCACAGCTTGGCACAGGCTCTCTCAGCTCAAGCCTCGG
GTCCTCCCTGGGACCCTGGGAGGCCAGGCCCTGCATCTGAGGTCCTGGCTTTTGTCAAGG
CAGGGCCCTGCAGAGACAGGTGGGCAGGGCCAGCCCCAGGGCCCTGGGCTTCGAACCCGG
CTGCTGATCACAGGCCTGTTCGGGGCTGGACTCGGTGGGGCCTGGCTGGCCCTGAGGGCT
GAGAAGGAGAGGCTGCAGCAGCAAAAGCGAACAGAAGCCCTGCGCCAGGCAGCTGTGGGC
CAGGGCGACTTCCACCTGCTGGATCACAGAGGCCGGGCTCGCTGCAAGGCTGACTTCCGG
GGCCAGTGGGTGCTGATGTACTTTGGCTTCACTCACTGCCCTGACATCTGCCCAGACGAG
CTGGAGAAGCTGGTGCAGGTGGTGCGGCAGCTGGAAGCAGAGCCTGGTTTGCCTCCAGTG
CAGCCTGTCTTCATCACTGTGGACCCCGAGCGGGACGACGTTGAAGCCATGGCCCGCTAC
GTCCAGGACTTCCACCCAAGACTGTTGGGTCTGACCGGCTCCACCAAACAGGTTGCCCAG
GCTAGTCACAGTTACCGCGTGTACTACAATGCAGGCCCCAAGGATGAGGACCAGGACTAC
ATCGTGGACCACTCCATTGCCATCTACCTGCTCAACCCTGACGGCCTCTTCACGGATTAC
TACGGCCGGAGCAGATCGGCTGAGCAGATCTCAGACAGTGTGCGGCGGCACATGGCGGCT
TTCCGCAGTGTCCTGTCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 266 |
| Molecular Weight
| 29809.7 |
| Theoretical pI
| 9.07 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein SCO2 homolog, mitochondrial
MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTR
LLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFR
GQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARY
VQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDY
YGRSRSAEQISDSVRRHMAAFRSVLS
|
| External Links |
|---|
| GenBank ID Protein
| 6175867 |
| UniProtKB/Swiss-Prot ID
| O43819 |
| UniProtKB/Swiss-Prot Entry Name
| SCO2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF177385 |
| GeneCard ID
| SCO2 |
| GenAtlas ID
| SCO2 |
| HGNC ID
| HGNC:10604 |
| References |
|---|
| General References
| Not Available |