| Identification |
|---|
| HMDB Protein ID
| CDBP03457 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cytochrome c oxidase copper chaperone |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| COX17 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in copper ion binding |
| Specific Function
| Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX |
| GO Classification
|
| Component |
| membrane-enclosed lumen |
| organelle envelope lumen |
| mitochondrial intermembrane space |
| Function |
| binding |
| transition metal ion binding |
| copper chaperone activity |
| copper ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| Process |
| copper ion transport |
| establishment of localization |
| transport |
| ion transport |
| cation transport |
| metal ion transport |
| transition metal ion transport |
|
| Cellular Location
|
- Mitochondrion intermembrane space
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q13.33 |
| SNPs
| COX17 |
| Gene Sequence
|
>192 bp
ATGCCGGGTCTGGTTGACTCAAACCCTGCCCCGCCTGAGTCTCAGGAGAAGAAGCCGCTG
AAGCCCTGCTGCGCTTGCCCGGAGACCAAGAAGGCGCGCGATGCGTGTATCATCGAGAAA
GGAGAAGAACACTGTGGACATCTAATTGAGGCCCACAAGGAATGCATGAGAGCCCTAGGA
TTTAAAATATGA
|
| Protein Properties |
|---|
| Number of Residues
| 63 |
| Molecular Weight
| 6915.0 |
| Theoretical pI
| 7.3 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cytochrome c oxidase copper chaperone
MPGLVDSNPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALG
FKI
|
| External Links |
|---|
| GenBank ID Protein
| 9049966 |
| UniProtKB/Swiss-Prot ID
| Q14061 |
| UniProtKB/Swiss-Prot Entry Name
| COX17_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF269244 |
| GeneCard ID
| COX17 |
| GenAtlas ID
| COX17 |
| HGNC ID
| HGNC:2264 |
| References |
|---|
| General References
| Not Available |