| Identification |
|---|
| HMDB Protein ID
| CDBP03444 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein tweety homolog 3 |
| Description
| Not Available |
| Synonyms
|
- hTTY3
|
| Gene Name
| TTYH3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chloride channel activity |
| Specific Function
| Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7p22 |
| SNPs
| TTYH3 |
| Gene Sequence
|
>1572 bp
ATGGCCGGGGTCAGCTACGCGGCGCCCTGGTGGGTGAGCCTCCTGCACCGGCTGCCCCAC
TTCGACCTGAGCTGGGAGGCCACTAGCAGCCAGTTCCGGCCCGAGGACACCGACTACCAG
CAGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGCCTGCCTCGCCCTGGACCTCCTCTTC
CTGCTCTTCTACTCCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGAC
GCCGACTGCTGCTGCACGGCCTGGTGTGTCATCATCGCCACGCTGGTGTGCAGCGCCGGC
ATCGCAGTGGGATTCTACGGCAACGGGGAGACCAGTGATGGCATCCATAGGGCCACCTAC
TCGCTCCGCCACGCCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCG
GTGGGGCTGAACCACACGGCGGAGCCCAGCCTGCAGACCCTGGAGCGGCAGCTGGCCGGG
CGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCAGGGCCTGCTGGAGACGCTGCTGGGC
TACACGGCCGCCATCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAG
CAGGTGGATCTCTACGACTGGTACAGGTGGCTGGGCTACCTGGGCCTGCTGCTGCTGGAC
GTCATCATCTGCCTCCTGGTGCTGGTTGGCCTCATCCGCAGCTCCAAGGGCATCCTGGTG
GGGGTCTGCCTGCTGGGAGTCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAG
CTGGCTGTGTCCGTGGGCTCCAGCGACTTCTGTGTGGACCCTGACGCCTACGTGACCAAA
ATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACATCCTGCAGTACTACCTGGCCTGCTCG
CCCCGCGCCGCCAACCCCTTCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAG
ATGCAGGATGTCGTGGCTGAGCTTCTGAGGACCGTCCCCTGGGAGCAGCCGGCCACTAAG
GACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGGCACGGAGGTGAACCTGCAGCACCTC
ACCGCCCTGGTGGACTGCCGCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTC
TGCTATGACGGCGTGGAGGGCCTCATCTACCTGGCCCTCTTCTCCTTCGTCACAGCCCTC
ATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACACCTGGCAGCAAAAGAGAGGCCCTGAT
GAGGACGGGGAGGAGGAGGCCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGC
GTCCACATGCCCAGCCTGTACAGCTGTGGCAGCAGCTACGGCAGTGAGACCAGCATCCCG
GCCGCGGCCCACACCGTCAGCAACGCCCCGGTCACTGAGTACATGAGCCAGAACGCTAAT
TTCCAGAACCCCCGCTGTGAGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCA
TACACCTCCAGCATGAGAGCCAAATACCTCGCCACGAGCCAGCCTCGCCCTGACTCCAGC
GGCAGCCACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 523 |
| Molecular Weight
| 57544.1 |
| Theoretical pI
| 5.05 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["43-63", "87-107", "212-232", "237-257", "387-407"]
|
| Protein Sequence
|
>Protein tweety homolog 3
MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLF
LLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATY
SLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLG
YTAAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILV
GVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACS
PRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHL
TALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPD
EDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNAN
FQNPRCENTPLIGRESPPPSYTSSMRAKYLATSQPRPDSSGSH
|
| External Links |
|---|
| GenBank ID Protein
| 51100978 |
| UniProtKB/Swiss-Prot ID
| Q9C0H2 |
| UniProtKB/Swiss-Prot Entry Name
| TTYH3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_025250.2 |
| GeneCard ID
| TTYH3 |
| GenAtlas ID
| TTYH3 |
| HGNC ID
| HGNC:22222 |
| References |
|---|
| General References
| Not Available |