Showing Protein Solute carrier family 12 member 8 (CDBP03439)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP03439
Secondary Accession Numbers Not Available
Name Solute carrier family 12 member 8
Description Not Available
Synonyms
  1. Cation-chloride cotransporter 9
Gene Name SLC12A8
Protein Type Enzyme
Biological Properties
General Function Involved in transport
Specific Function Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation
GO Classification
Component
membrane
cell part
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3q21.2
SNPs SLC12A8
Gene Sequence 
>2145 bp
ATGACCCAGATGTCCCAGGTGCAGGAGCTCTTCCATGAGGCAGCCCAGCAGGATGCCCTG
GCCCAGCCCCAGCCCTGGTGGAAGACCCAGCTGTTCATGTGGGAGCCTGTGCTGTTTGGG
ACCTGGGATGGTGTGTTCACATCCTGCATGATCAACATCTTTGGGGTTGTGCTCTTCCTG
AGGACTGGCTGGCTGGTGGGAAACACAGGAGTGCTCCTGGGCATGTTCCTGGTGTCCTTC
GTCATCCTGGTGGCCCTCGTCACGGTGCTGTCTGGCATTGGCGTCGGGGAGCGCAGCAGC
ATCGGCAGCGGTGGCGTCTACTCCATGATCTCCTCGGTCCTGGGTGGGCAGACGGGAGGC
ACCATCGGGCTGCTCTATGTGTTTGGACAGTGTGTTGCAGGTGCCATGTATATCACCGGC
TTTGCTGAATCCATCTCGGATTTGCTGGGCCTCGGGAATATCTGGGCTGTGCGAGGAATT
TCAGTTGCGGTGCTTCTGGCCTTGCTGGGCATTAACCTCGCAGGTGTCAAATGGATAATC
CGCCTCCAGCTGCTGTTGCTGTTCCTGCTGGCCGTGTCCACACTGGACTTTGTGGTGGGT
TCTTTCACCCACCTGGACCCAGAACATGGTTTCATTGGATATTCACCCGAACTGCTACAG
AACAACACGCTGCCCGATTACAGCCCGGGGGAATCTTTTTTCACTGTCTTTGGGGTTTTC
TTCCCAGCGGCTACAGGAGTCATGGCCGGCTTCAACATGGGGGGCGACCTCAGGGAGCCT
GCCGCCAGCATTCCCCTGGGCTCCCTGGCAGCTGTTGGCATCTCGTGGTTTCTGTACATC
GTCTTCGTCTTCCTCCTGGGCGCCATCTGCACTCGAGAGGCCCTTCGCTATGACTTCCTG
ATAGCGGAAAAGGTATCCCTCATGGGCTTCCTGTTCCTTTTGGGCTTATACATCTCGTCC
CTGGCTTCCTGCATGGGAGGACTTTATGGAGCTCCCCGCATCCTGCAGTGCATTGCCCAG
GAGAAAGTGATCCCTGCACTTGCCTGTCTGGGACAAGGGAAGGGGCCAAACAAAACACCC
GTGGCTGCCATCTGCCTGACCAGCTTGGTGACCATGGCCTTTGTTTTTGTGGGTCAAGTG
AACGTTCTGGCCCCCATCGTCACCATCAACTTCATGCTGACATACGTTGCAGTGGACTAC
TCTTACTTCTCCCTGTCCATGTGTTCCTGCAGCCTGACCCCGGTGCCTGAGCCGGTGCTC
AGGGAGGGCGCAGAAGGCCTCCACTGCTCTGAGCACCTGCTCTTAGAGAAAGCTCCCAGT
TACGGCTCTGAGGGACCTGCCCAAAGAGTCTTGGAGGGCACGCTACTGGAATTCACCAAG
GACATGGATCAGCTCCTCCAGCTAACCAGGAAGCTTGAGAGTAGCCAGCCCAGGCAAGGA
GAGGGTAACAGGACCCCAGAAAGTCAGAAGAGGAAAAGCAAGAAGGCCACCAAGCAGACC
CTACAAGATAGCTTCCTCTTGGACCTCAAATCCCCTCCTTCTTTCCCTGTCGAGATCTCT
GACAGGTTGCCCGCTGCCTCCTGGGAGGGGCAGGAGTCCTGCTGGAACAAGCAGACTTCC
AAGAGCGAAGGGACTCAGCCTGAGGGAACATATGGAGAGCAACTTGTTCCTGAGCTGTGC
AACCAATCAGAGTCCAGTGGAGAAGATTTCTTCCTGAAGTCCAGGCTCCAAGAACAAGAT
GTCTGGAGAAGATCCACTTCTTTCTATACCCACATGTGCAACCCCTGGGTCTCCCTGTTG
GGGGCTGTTGGGTCCCTTCTCATCATGTTTGTGATACAGTGGGTGTATACCCTGGTTAAC
ATGGGTGTTGCTGCCATCGTGTATTTCTACATTGGCCGGGCCAGTCCAGGGCTTCACCTT
GGATCAGCCTCCAACTTCAGCTTTTTCCGGTGGATGAGGTCTCTCTTGCTCCCCTCCTGC
AGGAGCTTGCGGTCCCCTCAGGAGCAGATCATCTTGGCGCCGTCCCTGGCTAAGGTTGAC
ATGGAGATGACTCAGCTCACCCAGGAGAATGCAGACTTCGCCACTCGGGATCGCTACCAC
CACTCCTCCCTCGTGAACCGGGAGCAGCTGATGCCTCACTACTAG
Protein Properties
Number of Residues 714
Molecular Weight 78222.1
Theoretical pI 5.5
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["37-60", "72-93", "99-116", "123-142", "154-173", "185-205", "233-254", "266-289", "309-331", "360-377", "383-403", "593-616", "622-643"]
Protein Sequence 
>Solute carrier family 12 member 8
MTQMSQVQELFHEAAQQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFL
RTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGG
TIGLLYVFGQCVAGAMYITGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWII
RLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVF
FPAATGVMAGFNMGGDLREPAASIPPGSLAAVGISWFLYIIFVFLLGAICTREALRYDFL
IAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTP
VAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVL
REGAEGLHCSEHLLLEKAPSYGSEGPAQRVLEGTLLEFTKDMDQLLQLTRKLESSQPRQG
EGNRTPESQKRKSKKATKQTLQDSFLLDLKSPPSFPVEISDRLPAASWEGQESCWNKQTS
KSEGTQPEGTYGEQLVPELCNQSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLL
GAVGSLLIMFVIQWVYTLVNMGVAAIVYFYIGRASPGLHLGSASNFSFFRWMRSLLLPSC
RSLRSPQEQIILAPSLAKVDMEMTQLTQENADFATRDRYHHSSLVNREQLMPHY
GenBank ID Protein 306774092
UniProtKB/Swiss-Prot ID A0AV02
UniProtKB/Swiss-Prot Entry Name S12A8_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001195483.1
GeneCard ID SLC12A8
GenAtlas ID SLC12A8
HGNC ID HGNC:15595
References
General References Not Available