Showing Protein Chloride intracellular channel protein 1 (CDBP03404)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP03404
Secondary Accession Numbers Not Available
Name Chloride intracellular channel protein 1
Description Not Available
Synonyms
  1. Chloride channel ABP
  2. NCC27
  3. Nuclear chloride ion channel 27
  4. Regulatory nuclear chloride ion channel protein
  5. hRNCC
Gene Name CLIC1
Protein Type Transporter
Biological Properties
General Function Involved in voltage-gated chloride channel activity
Specific Function Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle
GO Classification
Component
membrane
cell part
Function
voltage-gated chloride channel activity
anion channel activity
chloride channel activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
ion channel activity
Process
establishment of localization
transport
chloride transport
anion transport
inorganic anion transport
ion transport
Cellular Location
  1. Cell membrane
  2. Nucleus
  3. Cytoplasm
  4. Nucleus membrane
  5. Single-pass membrane protein (Probable)
  6. Single-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6p21.3
SNPs CLIC1
Gene Sequence 
>726 bp
ATGGCTGAAGAACAACCGCAGGTCGAATTGTTCGTGAAGGCTGGCAGTGATGGGGCCAAG
ATTGGGAACTGCCCATTCTCCCAGAGACTGTTCATGGTACTGTGGCTCAAGGGAGTCACC
TTCAATGTTACCACCGTTGACACCAAAAGGCGGACCGAGACAGTGCAGAAGCTGTGCCCA
GGGGGGCAGCTCCCATTCCTGCTGTATGGCACTGAAGTGCACACAGACACCAACAAGATT
GAGGAATTTCTGGAGGCAGTGCTGTGCCCTCCCAGGTACCCCAAGCTGGCAGCTCTGAAC
CCTGAGTCCAACACAGCTGGGCTGGACATATTTGCCAAATTTTCTGCCTACATCAAGAAT
TCAAACCCAGCACTCAATGACAATCTGGAGAAGGGACTCCTGAAAGCCCTGAAGGTTTTA
GACAATTACTTAACATCCCCCCTCCCAGAAGAAGTGGATGAAACCAGTGCTGAAGATGAA
GGTGTCTCTCAGAGGAAGTTTTTGGATGGCAACGAGCTCACCCTGGCTGACTGCAACCTG
TTGCCAAAGTTACACATAGTACAGGTGGTGTGTAAGAAGTACCGGGGATTCACCATCCCC
GAGGCCTTCCGGGGAGTGCATCGGTACTTGAGCAATGCCTACGCCCGGGAAGAATTCGCT
TCCACCTGTCCAGATGATGAGGAGATCGAGCTCGCCTATGAGCAAGTGGCAAAGGCCCTC
AAATAA
Protein Properties
Number of Residues 241
Molecular Weight 26922.5
Theoretical pI 4.82
Pfam Domain Function Not Available
Signals
  • ["None"]
Transmembrane Regions
  • ["26-46"]
Protein Sequence 
>Chloride intracellular channel protein 1
MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP
GGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN
SNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL
LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL
K
GenBank ID Protein 4426567
UniProtKB/Swiss-Prot ID O00299
UniProtKB/Swiss-Prot Entry Name CLIC1_HUMAN
PDB IDs
GenBank Gene ID AF034607
GeneCard ID CLIC1
GenAtlas ID CLIC1
HGNC ID HGNC:2062
References
General References Not Available