Showing Protein Relaxin-3 receptor 1 (CDBP03381)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP03381
Secondary Accession Numbers Not Available
Name Relaxin-3 receptor 1
Description Not Available
Synonyms
  1. G protein-coupled receptor SALPR
  2. G-protein coupled receptor GPCR135
  3. RLN3 receptor 1
  4. Relaxin family peptide receptor 3
  5. Somatostatin- and angiotensin-like peptide receptor
Gene Name RXFP3
Protein Type Receptor
Biological Properties
General Function Involved in G-protein coupled receptor protein signaling pathway
Specific Function Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
receptor activity
n-formyl peptide receptor activity
molecular transducer activity
signal transducer activity
peptide receptor activity
peptide receptor activity, g-protein coupled
Process
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5p15.1-p14
SNPs RXFP3
Gene Sequence 
>1410 bp
ATGCAGATGGCCGATGCAGCCACGATAGCCACCATGAATAAGGCAGCAGGCGGGGACAAG
CTAGCAGAACTCTTCAGTCTGGTCCCGGACCTTCTGGAGGCGGCCAACACGAGTGGTAAC
GCGTCGCTGCAGCTTCCGGACTTGTGGTGGGAGCTGGGGCTGGAGTTGCCGGACGGCGCG
CCGCCAGGACATCCCCCGGGCAGCGGCGGGGCAGAGAGCGCGGACACAGAGGCCCGGGTG
CGGATTCTCATCAGCGTGGTGTACTGGGTGGTGTGCGCCCTGGGGTTGGCGGGCAACCTG
CTGGTTCTCTACCTGATGAAGAGCATGCAGGGCTGGCGCAAGTCCTCTATCAACCTCTTC
GTCACCAACCTGGCGCTGACGGACTTTCAGTTTGTGCTCACCCTGCCCTTCTGGGCGGTG
GAGAACGCTCTTGACTTCAAATGGCCCTTCGGCAAGGCCATGTGTAAGATCGTGTCCATG
GTGACGTCCATGAACATGTACGCCAGCGTGTTCTTCCTCACTGCCATGAGTGTGACGCGC
TACCATTCGGTGGCCTCGGCTCTGAAGAGCCACCGGACCCGAGGACACGGCCGGGGCGAC
TGCTGCGGCCGGAGCCTGGGGGACAGCTGCTGCTTCTCGGCCAAGGCGCTGTGTGTGTGG
ATCTGGGCTTTGGCCGCGCTGGCCTCGCTGCCCAGTGCCATTTTCTCCACCACGGTCAAG
GTGATGGGCGAGGAGCTGTGCCTGGTGCGTTTCCCGGACAAGTTGCTGGGCCGCGACAGG
CAGTTCTGGCTGGGCCTCTACCACTCGCAGAAGGTGCTGCTGGGCTTCGTGCTGCCGCTG
GGCATCATTATCTTGTGCTACCTGCTGCTGGTGCGCTTCATCGCCGACCGCCGCGCGGCG
GGGACCAAAGGAGGGGCCGCGGTAGCCGGAGGACGCCCGACCGGAGCCAGCGCCCGGAGA
CTGTCGAAGGTCACCAAATCAGTGACCATCGTTGTCCTGTCCTTCTTCCTGTGTTGGCTG
CCCAACCAGGCGCTCACCACCTGGAGCATCCTCATCAAGTTCAACGCGGTGCCCTTCAGC
CAGGAGTATTTCCTGTGCCAGGTATACGCGTTCCCTGTGAGCGTGTGCCTAGCGCACTCC
AACAGCTGCCTCAACCCCGTCCTCTACTGCCTCGTGCGCCGCGAGTTCCGCAAGGCGCTC
AAGAGCCTGCTGTGGCGCATCGCGTCTCCTTCGATCACCAGCATGCGCCCCTTCACCGCC
ACTACCAAGCCGGAGCACGAGGATCAGGGGCTGCAGGCCCCGGCGCCGCCCCACGCGGCC
GCGGAGCCGGACCTGCTCTACTACCCACCTGGCGTCGTGGTCTACAGCGGGGGGCGCTAC
GACCTGCTGCCCAGCAGCTCTGCCTACTGA
Protein Properties
Number of Residues 469
Molecular Weight 51123.2
Theoretical pI 8.93
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["82-102", "120-140", "157-177", "216-236", "271-291", "330-350", "357-377"]
Protein Sequence 
>Relaxin-3 receptor 1
MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA
PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF
VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR
YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK
VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA
GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS
QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA
TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY
GenBank ID Protein 29824922
UniProtKB/Swiss-Prot ID Q9NSD7
UniProtKB/Swiss-Prot Entry Name RL3R1_HUMAN
PDB IDs Not Available
GenBank Gene ID AY236541
GeneCard ID RXFP3
GenAtlas ID RXFP3
HGNC ID HGNC:24883
References
General References Not Available