| Identification |
|---|
| HMDB Protein ID
| CDBP03378 |
| Secondary Accession Numbers
| Not Available |
| Name
| FMRFamide-related peptides |
| Description
| Not Available |
| Synonyms
|
- Neuropeptide NPSF
- Neuropeptide NPVF
- Neuropeptide RFRP-1
- Neuropeptide RFRP-2
- Neuropeptide RFRP-3
- Neuropeptide VF
|
| Gene Name
| NPVF |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor activity |
| Specific Function
| Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide NPSF induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced analgesia |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7p21-p15 |
| SNPs
| NPVF |
| Gene Sequence
|
>591 bp
ATGGAAATTATTTCATCAAAACTATTCATTTTATTGACTTTAGCCACTTCAAGCTTGTTA
ACATCAAACATTTTTTGTGCAGATGAATTAGTGATGTCCAATCTTCACAGCAAAGAAAAT
TATGACAAATATTCTGAGCCTAGAGGATACCCAAAAGGGGAAAGAAGCCTCAATTTTGAG
GAATTAAAAGATTGGGGACCAAAAAATGTTATTAAGATGAGTACACCTGCAGTCAATAAA
ATGCCACACTCCTTCGCCAACTTGCCATTGAGATTTGGGAGGAACGTTCAAGAAGAAAGA
AGTGCTGGAGCAACAGCCAACCTGCCTCTGAGATCTGGAAGAAATATGGAGGTGAGCCTC
GTGAGACGTGTTCCTAACCTGCCCCAAAGGTTTGGGAGAACAACAACAGCCAAAAGTGTC
TGCAGGATGCTGAGTGATTTGTGTCAAGGATCCATGCATTCACCATGTGCCAATGACTTA
TTTTACTCCATGACCTGCCAGCACCAAGAAATCCAGAATCCCGATCAAAAACAGTCAAGG
AGACTGCTATTCAAGAAAATAGATGATGCAGAATTGAAACAAGAAAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 196 |
| Molecular Weight
| 22326.4 |
| Theoretical pI
| 9.52 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>FMRFamide-related peptides
MEIISSKLFILLTLATSSLLTSNIFCADELVMSNLHSKENYDKYSEPRGYPKGERSLNFE
ELKDWGPKNVIKMSTPAVNKMPHSFANLPLRFGRNVQEERSAGATANLPLRSGRNMEVSL
VRRVPNLPQRFGRTTTAKSVCRMLSDLCQGSMHSPCANDLFYSMTCQHQEIQNPDQKQSR
RLLFKKIDDAELKQEK
|
| External Links |
|---|
| GenBank ID Protein
| 11125708 |
| UniProtKB/Swiss-Prot ID
| Q9HCQ7 |
| UniProtKB/Swiss-Prot Entry Name
| RFRP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB040290 |
| GeneCard ID
| NPVF |
| GenAtlas ID
| NPVF |
| HGNC ID
| HGNC:13782 |
| References |
|---|
| General References
| Not Available |