| Identification |
|---|
| HMDB Protein ID
| CDBP03366 |
| Secondary Accession Numbers
| Not Available |
| Name
| Myomegalin |
| Description
| Not Available |
| Synonyms
|
- Cardiomyopathy-associated protein 2
- Phosphodiesterase 4D-interacting protein
|
| Gene Name
| PDE4DIP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Replication, recombination and repair |
| Specific Function
| May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Cytoplasm
- Cytoplasm
- Golgi apparatus
- cytoskeleton
- centrosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q12 |
| SNPs
| PDE4DIP |
| Gene Sequence
|
>7041 bp
ATGTCTAATGGATATCGCACTCTGTCCCAGCACCTCAATGACCTGAAGAAGGAGAACTTC
AGCCTCAAGCTGCGCATCTACTTCCTGGAGGAGCGCATGCAACAGAAGTATGAGGCCAGC
CGGGAGGACATCTACAAGCGGAACATTGAGCTGAAGGTTGAAGTGGAGAGCTTGAAACGA
GAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGGGCTGATGTGGAGAATCTCAAC
AGTCAGAATGAAGCTGAGCTCCGACGCCAGTTTGAGGAGCGACAGCAGGAGACGGAGCAT
GTTTATGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAGGAGGAATCCAGGCTAGCAAAG
AATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAGAAGGAGTGTAACCTGGAGCTC
TCAGAGAAACTGAAGGGAGTCACCAAAAACTGGGAAGATGTACCAGGAGACCAGGTCAAG
CCCGACCAATACACTGAGGCCCTGGCCCAGAGGGACAAGAGAATTGAAGAACTGAATCAG
AGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCTCGGGAGAAACAACAACTGCTA
CATCTGTTGGAGGAGCCAACTAGCATGGAAGTGCAGCCCATGACTGAAGAGTTGCTGAAA
CAACAAAAGCTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATCTGATTCCCAC
TTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAG
AAACTTAATGAAATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGAT
GGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGACTGAGGAGTTG
TACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAA
AGCCAGCTTGGACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCT
CTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAAGCTCCAGAGG
GTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAG
GCTGCAGCACACGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTG
CGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACAGCTTCGTGCC
TGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAAC
CATAGTCTGAGTCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGA
GATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACTTCGCCAGCGA
ATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAA
GAGAAAGAAAAAGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTA
GAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTATGGAGAGTCTC
CTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGG
CTGAAAGAAGAAATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATT
CAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCTTAGTGCAACA
CTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTA
CAGCGAAAGGAAAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAA
CATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCAGGAAAGCCAA
GCTGCTGCAGAGAAGTTGGTGCAAGCCTTAATGGAAAGAAATTCAGAATTACAGGCCCTG
CGCCAATATTTAGGAGGGAGAGACTCCCTGATGTCCCAAGCACCCATCTCTAACCAACAA
GCTGAAGTTACCCCCACTGGCTGTCTTGGAAAACAGACTGATCAAGGTTCAATGCAGATA
CCTTCCAGAGATGATAGCACTTCATTGACTGCCAAAGAGGATGTCAGCATACCCAGATCC
ACATTAGGAGACTTGGACACAGTTGCAGGGCTGGAAAAAGAACTGAGTAATGCCAAAGAG
GAACTTGAACTCATGGCTAAAAAAGAAAGAGAAAGTCAGATGGAACTTTCTGCTCTACAG
TCCATGATGGCTGTGCAGGAAGAAGAGCTGCAGGTGCAGGCTGCTGATATGGAGTCTCTG
ACCAGGAACATACAGATTAAAGAAGATCTCATAAAGGACCTGCAAATGCAACTGGTTGAT
CCTGAAGACATACCAGCTATGGAACGCCTGACCCAGGAAGTCTTACTTCTTCGGGAAAAA
GTTGCTTCAGTAGAATCCCAGGGTCAAGAAATTTCAGGAAACCGAAGACAACAGTTGCTG
CTGATGCTAGAAGGACTAGTAGATGAACGGAGTCGGCTCAATGAGGCCTTACAAGCAGAG
AGACAGCTCTATAGCAGTCTGGTGAAGTTCCATGCCCATCCAGAGAGCTCTGAGAGAGAC
CGAACTCTGCAGGTGGAACTGGAAGGGGCTCAGGTGTTACGCAGTCGGCTAGAAGAAGTT
CTTGGAAGAAGCTTGGAGCGCTTAAACAGGCTGGAGACCCTGGCCGCCATTGGAGGTGCA
GCTGCAGGGGATGACACCGAAGATACAAGCACTGAGTTCACTGACAGTATTGAGGAGGAG
GCTGCACACCATAGTCACCAGCAACTTGTCAAGGTGGCTTTGGAGAAAAGTCTGGCAACT
GTGGAGACCCAGAACCCATCTTTTTCCCCTCCTTCTCCGATGGGAGGGGACAGTAACAGG
TGTCTTCAGGAAGAAATGCTCCACCTGAGGGCTGAGTTCCACCAGCACTTAGAAGAGAAG
AGGAAAGCTGAGGAGGAACTGAAGGAGCTAAAGGCTCAAATTGAGGAAGCAGGATTCTCC
TCAGTGTCCCACATCAGGAACACCATGCTGAGCCTTTGCCTTGAGAATGCGGAGCTGAAA
GAGCAGATGGGAGAAGCAATGTCTGATGGATGGGAGATCGAGGAAGACAAGGAGAAGGGC
GAGGTGATGGTTGAGACTGTGGTAACCAAAGAGGGTCTGAGTGAGAGTAGCCTTCAGGCT
GAGTTCAGAAAGCTCCAGGGAAAACTGAAGAATGCCCACAATATCATCAACCTCCTCAAA
GAACAACTTGTGCTGAGTAGCAAGGAAGGGAATAGTAAACTTACTCCAGAGCTCCTTGTG
CATCTGACCAGCACCATTGAAAGAATAAACACAGAACTGGTTGGTTCCCCTGGGAAGCAC
CAACACCAAGAGGAGGGGAATGTGACTGTGAGGCCTTTCCCCAGACCCCAGAGCCTTGAC
CTTGGGGCTACCTTCACAGTGGATGCCCACCAATTGGATAACCAGTCCCAGCCTCGTGAC
CCTGGGCCTCAGTCAGCGTTTAGCCTACCAGGGTCCACCCAGCACCTGCGCTCCCAGCTG
TCACAATGCAAACAACGCTATCAAGATCTCCAGGAGAAGCTGCTGCTATCAGAAGCCACT
GTCTTTGCTCAGGCTAACGAGCTGGAGAAATACAGAGTTATGCTTACAGGTGAATCCTTG
GTGAAGCAGGACAGCAAGCAGATCCAGGTGGACCTCCAGGACCTGGGCTATGAGACTTGT
GGCCGAAGCGAGAATGAGGCTGAACGGGAGGAAACCACCAGTCCTGAGTGTGAGGAGCAC
AACAGCCTCAAGGAAATGGTCCTGATGGAGGGGCTGTGCTCTGAGCAGGGACGCCGGGGC
TCAACACTGGCTAGTTCCTCTGAGAGGAAGCCCTTGGAGAACCAGCTAGGGAAGCAGGAA
GAGTTCCGGGTATATGGAAAGTCAGAAAACATCTTGGTCCTACGAAAGGACATCAAAGAT
CTGAAGGCCCAGCTGCAGAATGCCAACAAGGTCATTCAAAACCTCAAGAGCCGGGTCCGG
TCCCTCTCAGTTACAAGTGATTATTCGTCTAGTCTGGAAAGACCCTGGAAGCTGAGAGCT
GTTGGCACCTTGGAGGGGTCTTCACCTCATAGTGTCCCTGATGAGGATGAGGGGTGGCTG
TCTGATGGCACTGGGGCTTTCTACTCTCCAGGGCTTCAGGCCAAAAAGGACCTGGAGAGT
CTCATCCAGAGAGTATCCCAGCTGGAGGCCCAGCTCCCAAAAAATGGACTAGAAGAGAAG
CTGGCTGAGGAGCTGAGATCAGCCTCGTGGCCTGGGAAATATGATTCCCTGATTCAGGAT
CAGGCCCGGGAACTGTCTTACCTACGGCAAAAAATACGAGAAGGGAGAGGTATTTGTTAT
CTTATCACCCGGCATGCAAAAGATACAGTAAAATCTTTTGAGGATCTCCTAAGGAGCAAT
GACATTGACTACTACCTGGGACAGAGCTTCCGGGAGCAACTCGCCCAGGGAAGCCAGCTG
ACAGAGAGGCTCACCAGCAAACTCAGCACCAAGGATCATAAAAGTGAGAAAGATCAAGCT
GGACTTGAGCCACTGGCCCTCAGGCTCAGCAGGGAGCTGCAGGAGAAGGAGAAAGTGATT
GAAGTCCTGCAGGCCAAGCTGGATGCTCGGTCCCTCACACCCTCCAGCAGCCATGCCTTG
TCTGACTCCCACCGCTCTCCCAGCAGCACCTCTTTCCTGTCTGATGAACTGGAAGCCTGC
TCTGACATGGACATAGTCAGCGAGTACACACACTATGAAGAGAAGAAAGCTTCTCCCAGT
CACTCAGATTCCATCCATCATTCGAGTCATTCTGCTGTGTTGTCTTCTAAACCATCATCA
ACCAGTGCATCTCAGGGGGCTAAGGCCGAATCCAACAGCAACCCCATCAGCTTGCCAACT
CCCCAGAATACCCCCAAGGAGGCCAACCAGGCCCATTCAGGCTTTCATTTTCACTCCATA
CCCAAGCTGGCTAGCCTTCCTCAGGCACCATTGCCCTCAGCTCCATCCAGCTTCCTGCCT
TTCAGCCCCACTGGCCCTCTCCTCCTTGGCTGCTGTGAGACACCAGTGGTCTCCTTGGCT
GAGGCTCAGCAGGAGCTACAGATGCTGCAGAAGCAGTTGGGAGAAAGTGCCAGCACTGTT
CCTCCTGCTTCCACAGCTACATTGCTGAGCAACGACTTGGAAGCCGACTCTTCCTACTAC
CTCAACTCTGCCCAGCCTCACTCTCCTCCAAGGGGCACCATAGAACTGGGAAGAATCCTA
GAGCCTGGGTACCTGGGCAGCAGTGGCAAGTGGGATGTGATGAGGCCTCAGAAAGGGAGT
GTATCTGGGGACCTATCCTCAGGCTCCTCTGTGTACCAGCTTAACTCCAAACCCACAGGG
GCTGACCTGCTGGAAGAGCATCTTGGTGAAATCCGGAACCTGCGCCAGCGCCTGGAGGAA
TCCATCTGCATCAATGACCGCCTACGGGAGCAACTGGAACACCGGCTGACCTCTACTGCT
CGTGGAAGGGGATCCACTTCTAACTTCTACAGTCAGGGCCTGGAGTCCATACCTCAGCTC
TGCAATGAGAACAGAGTCCTCAGGGAAGACAATCGAAGACTTCAGGCTCAACTGAGTCAT
GTTTCCAGAGAGCACTCCCAGGAAACAGAAAGCCTGAGGGAGGCTCTGCTGTCCTCTCGA
TCCCACCTTCAAGAGCTGGAAAAGGAGCTGGAGCACCAGAAGGTGGAAAGGCAGCAGCTT
TTGGAAGACTTGAGGGAGAAGCAGCAAGAGGTCTTGCATTTCAGGGAGGAACGTCTTTCC
CTCCAGGAAAACGACTCCAGACTGCAGCACAAGCTGGTTCTCCTGCAGCAACAGTGTGAA
GAGAAACAGCAGCTCTTTGAGTCCCTCCAGTCAGAGCTACAAATCTACGAGGCACTTTAT
GGCAATTCCAAGAAGGGGCTGAAAGCTTACAGCCTGGATGCCTGTCACCAAATCCCTTTG
AGCAGTGACCTGAGCCACCTGGTGGCAGAGGTACGAGCTCTGAGAGGGCAGCTGGAGCAG
AGCATTCAGGGGAACAATTGTCTGCGACTGCAGCTGCAACAGCAGCTGGAGAGCGGTGCT
GGCAAAGCCAGCCTCAGCCCCTCCTCCATTAACCAGAACTTCCCAGCCAGCACTGACCCT
GGAAACAAGCAGCTGCTCCTCCAAGATTCAGCTGTGTCCCCTCCAGTCCGGGATGTTGGT
ATGAATTCCCCAGCTCTGGTCTTCCCCAGCTCTGCTTCCTCTACTCCTGGCTCAGAAACG
CCCATAATCAACAGAGCAAATGGCTTGGGTTTGGATACTTCTCCAGTAATGAAGACCCCT
CCCAAGCTAGAGGGTGATGCTACTGATGGCTCCTTTGCCAATAAGCATGGCCGCCATGTC
ATTGGCCACATTGATGACTACAGTGCCCTAAGACAGCAGATTGCGGAGGGCAAGCTGCTG
GTCAAAAAGATAGTGTCTCTTGTGAGATCAGCGTGCAGCTTCCCTGGCCTTGAAGCCCAA
GGCACAGAGGTGCTAGGCAGCAAAGGTATTCATGAGCTTCGGAGCAGCACCAGTGCCCTG
CACCATGCCCTAGAGGAGTCAGCTTCCCTCCTCACCATGTTCTGGAGAGCGGCCCTGCCA
AGCACCCACATCCCTGTGCTGCCTGGCAAAGTGGGAGAATCAACAGAAAGGGAACTTCTG
GAACTGAGAACCAAAGTATCCAAACAGGAGCGACTCCTTCAGAGCACAACTGAGCATCTG
AAGAACGCCAACCAGCAGAAGGAGAGCATGGAACAGTTCATTGTCAGCCAGCTAACCAGA
ACACATGATGTTTTAAAGAAGGCAAGGACTAACTTAGAGGTGAAATCCCTAAGGGCTCTG
CCATGTACTCCAGCCTTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 2346 |
| Molecular Weight
| 265077.7 |
| Theoretical pI
| 5.14 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Myomegalin
MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR
ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK
NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQ
SLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSH
LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEEL
YQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQR
VVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRA
WEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQR
IHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESL
LRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSAT
LLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQ
AAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQI
PSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQ
SMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREK
VASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERD
RTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEE
AAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEK
RKAEEELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKG
EVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKLTPELLV
HLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRD
PGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESL
VKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRG
STLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVR
SLSVTSDYSSSLERPWKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLES
LIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICY
LITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQA
GLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEAC
SDMDIVSEYTHYEEKKASPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISLPT
PQNTPKEANQAHSGFHFHSIPKLASLPQAPLPSAPSSFLPFSPTGPLLLGCCETPVVSLA
EAQQELQMLQKQLGESASTVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRIL
EPGYLGSSGKWDVMRPQKGSVSGDLSSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRLEE
SICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH
VSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLS
LQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYSLDACHQIPL
SSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDP
GNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANGLGLDTSPVMKTP
PKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKLLVKKIVSLVRSACSFPGLEAQ
GTEVLGSKGIHELRSSTSALHHALEESASLLTMFWRAALPSTHIPVLPGKVGESTERELL
ELRTKVSKQERLLQSTTEHLKNANQQKESMEQFIVSQLTRTHDVLKKARTNLEVKSLRAL
PCTPAL
|
| External Links |
|---|
| GenBank ID Protein
| 157311604 |
| UniProtKB/Swiss-Prot ID
| Q5VU43 |
| UniProtKB/Swiss-Prot Entry Name
| MYOME_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_014644.4 |
| GeneCard ID
| PDE4DIP |
| GenAtlas ID
| PDE4DIP |
| HGNC ID
| HGNC:15580 |
| References |
|---|
| General References
| Not Available |