| Identification |
|---|
| HMDB Protein ID
| CDBP03352 |
| Secondary Accession Numbers
| Not Available |
| Name
| cAMP-dependent protein kinase type II-alpha regulatory subunit |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| PRKAR2A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cAMP-dependent protein kinase regulator activity |
| Specific Function
| Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase |
| GO Classification
|
| Component |
| macromolecular complex |
| protein complex |
| camp-dependent protein kinase complex |
| Function |
| enzyme regulator activity |
| kinase regulator activity |
| protein kinase regulator activity |
| camp-dependent protein kinase regulator activity |
| Process |
| regulation of cellular protein metabolic process |
| regulation of protein modification process |
| regulation of protein amino acid phosphorylation |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of cellular process |
| signal transduction |
| regulation of cellular metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p21.3-p21.2 |
| SNPs
| PRKAR2A |
| Gene Sequence
|
>1215 bp
ATGAGCCACATCCAGATCCCGCCGGGGCTCACGGAGCTGCTGCAGGGCTACACGGTGGAG
GTGCTGCGACAGCAGCCGCCTGACCTCGTCGAATTCGCAGTGGAGTACTTCACCCGCCTG
CGCGAGGCCCGCGCCCCAGCCTCAGTCCTGCCCGCCGCCACCCCACGCCAGAGCCTGGGC
CACCCCCCGCCAGAACCCGGCCCGGACCGTGTCGCCGACGCCAAAGGGGACAGCGAGTCG
GAGGAGGACGAGGACTTGGAAGTTCCAGTTCCTAGCAGATTTAATAGACGAGTATCAGTC
TGTGCTGAGACCTATAACCCTGATGAGGAAGAGGAAGATACAGATCCAAGGGTGATTCAT
CCTAAAACTGATGAACAGAGATGCAGACTTCAGGAAGCTTGCAAAGATATTCTCCTTTTC
AAAAATCTTGATCAGGAACAGCTTTCTCAAGTTCTCGATGCCATGTTTGAAAGGATAGTC
AAAGCTGATGAGCATGTCATTGACCAAGGAGATGATGGAGACAACTTTTATGTCATAGAA
CGGGGAACTTATGACATTTTAGTAACAAAAGATAATCAAACCCGCTCTGTTGGTCAATAT
GACAACCGTGGCAGTTTTGGAGAACTAGCTCTGATGTACAACACCCCGAGAGCTGCTACC
ATTGTTGCTACCTCAGAAGGCTCCCTTTGGGGACTGGACCGGGTGACTTTTAGAAGAATC
ATAGTGAAAAATAATGCAAAGAAGAGGAAGATGTTTGAATCATTTATTGAGTCTGTGCCC
CTCCTTAAATCACTAGAGGTGTCAGAACGAATGAAGATTGTGGATGTAATAGGAGAGAAG
ATCTATAAGGATGGAGAACGCATAATCACTCAGGGTGAAAAGGCTGATAGCTTTTACATC
ATAGAGTCTGGCGAAGTGAGCATCTTGATTAGAAGCAGGACTAAATCAAACAAGGATGGT
GGGAACCAGGAGGTCGAGATTGCCCGCTGCCATAAGGGGCAGTACTTTGGAGAGCTTGCC
CTGGTCACCAACAAACCCAGAGCTGCCTCAGCTTATGCAGTTGGAGATGTCAAATGCTTA
GTTATGGATGTACAAGCATTCGAGAGGCTTCTGGGGCCCTGCATGGACATCATGAAGAGG
AACATCTCACACTATGAGGAACAGCTGGTGAAGATGTTTGGCTCCAGCGTGGATCTGGGC
AACCTCGGGCAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 404 |
| Molecular Weight
| 45518.0 |
| Theoretical pI
| 4.7 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>cAMP-dependent protein kinase type II-alpha regulatory subunit
MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG
HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH
PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE
RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI
IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI
IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL
VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ
|
| External Links |
|---|
| GenBank ID Protein
| 29648 |
| UniProtKB/Swiss-Prot ID
| P13861 |
| UniProtKB/Swiss-Prot Entry Name
| KAP2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X14968 |
| GeneCard ID
| PRKAR2A |
| GenAtlas ID
| PRKAR2A |
| HGNC ID
| HGNC:9391 |
| References |
|---|
| General References
| Not Available |