| Identification |
|---|
| HMDB Protein ID
| CDBP03343 |
| Secondary Accession Numbers
| Not Available |
| Name
| Glycoprotein hormone alpha-2 |
| Description
| Not Available |
| Synonyms
|
- Putative secreted protein Zsig51
- Thyrostimulin subunit alpha
|
| Gene Name
| GPHA2 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in hormone activity |
| Specific Function
| Stimulates the thyroid. Binds and activates THSR, leads to increased cAMP production |
| GO Classification
|
| Component |
| extracellular region |
| Function |
| hormone activity |
| binding |
| protein binding |
| receptor binding |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q13.1 |
| SNPs
| GPHA2 |
| Gene Sequence
|
>390 bp
ATGCCTATGGCGTCCCCTCAAACCCTGGTCCTCTATCTGCTGGTCCTGGCAGTCACTGAA
GCCTGGGGCCAGGAGGCAGTCATCCCAGGCTGCCACTTGCACCCCTTCAATGTGACAGTG
CGAAGTGACCGCCAAGGCACCTGCCAGGGCTCCCACGTGGCACAGGCCTGTGTGGGCCAC
TGTGAGTCCAGCGCCTTCCCTTCTCGGTACTCTGTGCTGGTGGCCAGTGGTTACCGACAC
AACATCACCTCCGTCTCTCAGTGCTGCACCATCAGTGGCCTGAAGAAGGTCAAAGTACAG
CTGCAGTGTGTGGGGAGCCGGAGGGAGGAGCTCGAGATCTTCACGGCCAGGGCCTGCCAG
TGTGACATGTGTCGCCTCTCTCGCTACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 129 |
| Molecular Weight
| 14163.3 |
| Theoretical pI
| 8.27 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glycoprotein hormone alpha-2
MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGH
CESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQ
CDMCRLSRY
|
| External Links |
|---|
| GenBank ID Protein
| 14009506 |
| UniProtKB/Swiss-Prot ID
| Q96T91 |
| UniProtKB/Swiss-Prot Entry Name
| GPHA2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF260739 |
| GeneCard ID
| GPHA2 |
| GenAtlas ID
| GPHA2 |
| HGNC ID
| HGNC:18054 |
| References |
|---|
| General References
| Not Available |