| Identification |
|---|
| HMDB Protein ID
| CDBP03314 |
| Secondary Accession Numbers
| Not Available |
| Name
| Villin-1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| VIL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in actin binding |
| Specific Function
| Ca(2+)-regulated actin-binding protein |
| GO Classification
|
| Function |
| actin binding |
| binding |
| protein binding |
| cytoskeletal protein binding |
| Process |
| cytoskeleton organization |
| cellular process |
| cellular component organization at cellular level |
| organelle organization |
|
| Cellular Location
|
- Cytoplasm
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2q35 |
| SNPs
| VIL1 |
| Gene Sequence
|
>2484 bp
ATGACCAAGCTGAGCGCCCAAGTCAAAGGCTCTCTCAACATCACCACCCCGGGGCTGCAG
ATATGGAGGATCGAGGCCATGCAGATGGTGCCTGTTCCTTCCAGCACCTTTGGAAGCTTC
TTCGATGGTGACTGCTACATCATCCTGGCTATCCACAAGACAGCCAGCAGCCTGTCCTAT
GACATCCACTACTGGATTGGCCAGGACTCATCCCTGGATGAGCAGGGGGCAGCTGCCATC
TACACCACACAGATGGATGACTTCCTGAAGGGCCGGGCTGTGCAGCACCGCGAGGTCCAG
GGCAACGAGAGCGAGGCCTTCCGAGGCTACTTCAAGCAAGGCCTTGTGATCCGGAAAGGG
GGCGTGGCTTCTGGCATGAAGCACGTGGAGACCAACTCCTATGACGTCCAGAGGCTGCTG
CATGTCAAGGGCAAGAGGAACGTGGTAGCTGGAGAGGTAGAGATGTCCTGGAAGAGTTTC
AACCGAGGGGATGTTTTCCTCCTGGACCTTGGGAAGCTTATCATCCAGTGGAATGGACCG
GAAAGCACCCGTATGGAGAGACTCAGGGGCATGACTCTGGCCAAGGAGATCCGAGACCAG
GAGCGGGGAGGGCGCACCTATGTAGGCGTGGTGGACGGAGAGAATGAATTGGCATCCCCG
AAGCTGATGGAGGTGATGAACCACGTGCTGGGCAAGCGCAGGGAGCTGAAGGCGGCCGTG
CCCGACACGGTGGTGGAGCCGGCACTCAAGGCTGCACTCAAACTGTACCATGTGTCTGAC
TCCGAGGGGAATCTGGTGGTGAGGGAAGTCGCCACACGGCCACTGACACAGGACCTGCTC
AGTCACGAGGACTGTTACATCCTGGACCAGGGGGGCCTGAAGATCTACGTGTGGAAAGGG
AAGAAAGCCAATGAGCAGGAGAAGAAGGGAGCCATGAGCCATGCGCTGAACTTCATCAAA
GCCAAGCAGTACCCACCAAGCACACAGGTGGAGGTGCAGAATGATGGGGCTGAGTCGGCC
GTCTTTCAGCAGCTCTTCCAGAAGTGGACAGCGTCCAACCGGACCTCAGGCCTAGGCAAA
ACCCACACTGTGGGCTCCGTGGCCAAAGTGGAACAGGTGAAGTTCGATGCCACATCCATG
CATGTCAAGCCTCAGGTGGCTGCCCAGCAGAAGATGGTAGATGATGGGAGTGGGGAAGTG
CAGGTGTGGCGCATTGAGAACCTAGAGCTGGTACCTGTGGATTCCAAGTGGCTAGGCCAC
TTCTATGGGGGCGACTGCTACCTGCTGCTCTACACCTACCTCATCGGCGAGAAGCAGCAT
TACCTGCTCTACGTTTGGCAGGGCAGCCAGGCCAGCCAAGATGAAATTACAGCATCAGCT
TATCAAGCCGTCATCCTGGACCAGAAGTACAATGGTGAACCAGTCCAGATCCGGGTCCCA
ATGGGCAAGGAGCCACCTCATCTTATGTCCATCTTCAAGGGACGCATGGTGGTCTACCAG
GGAGGCACCTCCCGAACTAACAACTTGGAGACCGGGCCCTCCACACGGCTGTTCCAGGTC
CAGGGAACTGGCGCCAACAACACCAAGGCCTTTGAGGTCCCAGCGCGGGCCAATTTCCTC
AATTCCAATGATGTCTTTGTCCTCAAGACCCAGTCTTGCTGCTATCTATGGTGTGGGAAG
GGTTGTAGCGGGGACGAGCGGGAGATGGCCAAGATGGTTGCTGACACCATCTCCCGGACG
GAGAAGCAAGTGGTGGTGGAAGGGCAGGAGCCAGCCAACTTCTGGATGGCCCTGGGTGGG
AAGGCCCCCTATGCCAACACCAAGAGACTACAGGAAGAAAACCTGGTCATCACCCCCCGG
CTCTTTGAGTGTTCCAACAAGACTGGGCGCTTCCTGGCCACAGAGATCCCTGACTTCAAT
CAGGATGACTTGGAAGAGGATGATGTGTTCCTACTAGATGTCTGGGACCAGGTCTTCTTC
TGGATTGGGAAACATGCCAACGAGGAGGAGAAGAAGGCCGCAGCAACCACTGCACAGGAA
TACCTCAAGACCCATCCCAGCGGGCGTGACCCTGAGACCCCCATCATTGTGGTGAAGCAG
GGACACGAGCCCCCCACCTTCACAGGCTGGTTCCTGGCTTGGGATCCCTTCAAGTGGAGT
AACACCAAATCCTATGAGGACCTGAAGGCGGAGCTTGGCAACTCTAGGGACTGGAGCCAG
ATCACTGCTGAGGTCACAAGCCCCAAAGTGGACGTGTTCAATGCTAACAGCAACCTCAGT
TCTGGGCCTCTGCCCATCTTCCCCCTGGAGCAGCTAGTGAACAAGCCTGTAGAGGAGCTC
CCCGAGGGTGTGGACCCCAGCAGGAAGGAGGAACACCTGTCCATTGAAGATTTCACTCAG
GCCTTTGGGATGACTCCAGCTGCCTTCTCTGCTCTGCCTCGATGGAAGCAACAAAACCTC
AAGAAAGAAAAAGGACTATTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 827 |
| Molecular Weight
| 92694.6 |
| Theoretical pI
| 6.35 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Villin-1
MTKLSAQVKGSLNITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSY
DIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKG
GVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGP
ESTRMERLRGMTLAKEIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAV
PDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKG
KKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGK
THTVGSVAKVEQVKFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGH
FYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVP
MGKEPPHLMSIFKGRMVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFL
NSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGG
KAPYANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFF
WIGKHANEEEKKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWS
NTKSYEDLKAELGNSRDWSQITAEVTSPKVDVFNANSNLSSGPLPIFPLEQLVNKPVEEL
PEGVDPSRKEEHLSIEDFTQAFGMTPAAFSALPRWKQQNLKKEKGLF
|
| External Links |
|---|
| GenBank ID Protein
| 194394237 |
| UniProtKB/Swiss-Prot ID
| P09327 |
| UniProtKB/Swiss-Prot Entry Name
| VILI_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_007127.2 |
| GeneCard ID
| VIL1 |
| GenAtlas ID
| VIL1 |
| HGNC ID
| HGNC:12690 |
| References |
|---|
| General References
| Not Available |