| Identification |
| HMDB Protein ID
| CDBP03301 |
| Secondary Accession Numbers
| Not Available |
| Name
| Trypsin-2 |
| Description
| Not Available |
| Synonyms
|
- Anionic trypsinogen
- Serine protease 2
- Trypsin II
|
| Gene Name
| PRSS2 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in serine-type endopeptidase activity |
| Specific Function
| Preferential cleavage:Arg-|-Xaa, Lys-|-Xaa |
| GO Classification
|
| Function |
| hydrolase activity |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| endopeptidase activity |
| serine-type endopeptidase activity |
| catalytic activity |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein metabolic process |
| proteolysis |
|
| Cellular Location
|
- Secreted
- extracellular space
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q34 |
| SNPs
| PRSS2 |
| Gene Sequence
|
>744 bp
ATGAATCTACTCCTGATCCTTACCTTTGTTGCAGCTGCTGTTGCTGCCCCCTTTGATGAT
GATGACAAGATCGTTGGGGGCTACATCTGTGAGGAGAATTCTGTCCCCTACCAGGTGTCC
TTGAATTCTGGCTACCACTTCTGCGGTGGCTCCCTCATCAGCGAACAGTGGGTGGTGTCA
GCAGGTCACTGCTACAAGTCCCGCATCCAGGTGAGACTGGGAGAGCACAACATCGAAGTC
CTGGAGGGGAATGAACAGTTCATCAATGCGGCCAAGATCATCCGCCACCCCAAATACAAC
AGCCGGACTCTGGACAATGACATCCTGCTGATCAAGCTCTCCTCACCTGCCGTCATCAAT
TCCCGCGTGTCCGCCATCTCTCTGCCCACTGCCCCTCCAGCTGCTGGCACCGAGTCCCTC
ATCTCCGGCTGGGGCAACACTCTGAGTTCTGGTGCCGACTACCCAGACGAGCTGCAGTGC
CTGGATGCTCCTGTGCTGAGCCAGGCTGAGTGTGAAGCCTCCTACCCTGGAAAGATTACC
AACAACATGTTCTGTGTGGGCTTCCTCGAGGGAGGCAAGGATTCCTGCCAGGGTGATTCT
GGTGGCCCTGTGGTCTCCAATGGAGAGCTCCAAGGAATTGTCTCCTGGGGCTATGGCTGT
GCCCAGAAGAACAGGCCTGGAGTCTACACCAAGGTCTACAACTATGTGGACTGGATTAAG
GACACCATAGCTGCCAACAGCTAA
|
| Protein Properties |
| Number of Residues
| 247 |
| Molecular Weight
| 26487.6 |
| Theoretical pI
| 4.54 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Trypsin-2
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
DTIAANS
|
| External Links |
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P07478 |
| UniProtKB/Swiss-Prot Entry Name
| TRY2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M27602 |
| GeneCard ID
| PRSS2 |
| GenAtlas ID
| PRSS2 |
| HGNC ID
| HGNC:9483 |
| References |
| General References
| Not Available |