Showing Protein Short transient receptor potential channel 5 (CDBP03291)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03291
Secondary Accession Numbers Not Available
Name Short transient receptor potential channel 5
Description Not Available
Synonyms
  1. TRP-5
  2. Transient receptor protein 5
  3. TrpC5
  4. hTRP-5
  5. hTRP5
Gene Name TRPC5
Protein Type Receptor
Biological Properties
General Function Involved in ion channel activity
Specific Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion
GO Classification
Component
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
ion channel activity
cation channel activity
calcium channel activity
Process
di-, tri-valent inorganic cation transport
divalent metal ion transport
calcium ion transport
establishment of localization
transport
transmembrane transport
ion transport
cation transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs TRPC5
Gene Sequence 
>2922 bp
ATGGCCCAACTGTACTACAAAAAGGTCAACTACTCACCGTACAGAGACCGCATCCCCCTG
CAAATTGTGAGGGCTGAGACAGAGCTCTCTGCAGAGGAGAAGGCCTTCCTCAATGCTGTG
GAGAAGGGGGACTATGCCACTGTGAAGCAGGCCCTTCAGGAGGCTGAGATCTACTATAAT
GTTAACATCAACTGCATGGACCCCTTGGGCCGGAGTGCCCTGCTCATTGCCATTGAGAAC
GAGAACCTGGAGATCATGGAGCTACTGCTGAACCACAGCGTGTATGTGGGTGATGCATTG
CTCTATGCCATACGCAAGGAAGTGGTGGGCGCTGTGGAGCTTCTGCTCAGCTACAGGCGG
CCCAGCGGAGAGAAGCAGGTCCCCACTCTGATGATGGACACGCAGTTCTCTGAATTCACA
CCGGACATCACTCCCATCATGCTGGCTGCCCACACCAACAACTACGAAATCATCAAATTG
CTTGTCCAAAAACGGGTCACTATCCCACGGCCCCACCAGATCCGCTGCAACTGTGTGGAG
TGTGTGTCTAGTTCAGAGGTAGACAGCCTGCGCCACTCTCGCTCCCGACTGAACATCTAT
AAGGCTCTGGCAAGCCCCTCACTCATTGCCTTATCAAGTGAGGACCCCATCCTAACTGCC
TTCCGTCTGGGCTGGGAGCTCAAGGAGCTCAGCAAGGTGGAGAATGAGTTCAAGGCCGAG
TATGAGGAGCTCTCTCAGCAGTGCAAGCTCTTTGCCAAAGACCTGCTGGACCAAGCTCGG
AGCTCCAGGGAACTGGAGATCATCCTCAACCATCGAGATGACCACAGTGAAGAGCTTGAC
CCTCAGAAGTACCATGACCTGGCCAAGTTGAAGGTGGCAATCAAATACCACCAGAAAGAG
TTTGTTGCTCAGCCCAACTGCCAACAGTTGCTTGCCACCCTGTGGTATGATGGCTTCCCT
GGATGGCGGCGGAAACACTGGGTAGTCAAGCTTCTAACCTGCATGACCATTGGGTTCCTG
TTTCCCATGCTGTCTATAGCCTACCTGATCTCACCCAGGAGCAACCTTGGGCTGTTCATC
AAGAAACCCTTTATCAAGTTTATCTGCCACACAGCATCCTATTTGACCTTCCTCTTTATG
CTTCTCCTGGCTTCTCAGCACATTGTCAGGACAGACCTTCATGTACAGGGGCCTCCCCCA
ACTGTCGTGGAATGGATGATATTGCCTTGGGTTCTAGGTTTCATTTGGGGTGAGATTAAG
GAAATGTGGGATGGTGGATTTACTGAATACATCCATGACTGGTGGAACCTGATGGATTTT
GCAATGAACTCCCTCTACCTGGCAACTATTTCCCTGAAGATTGTGGCCTATGTCAAGTAT
AATGGTTCTCGTCCAAGGGAGGAATGGGAAATGTGGCACCCGACTCTGATTGCGGAAGCA
CTCTTCGCAATATCCAACATTTTAAGTTCGTTGCGTCTCATATCCCTGTTCACAGCCAAC
TCCCACTTAGGACCTCTGCAGATCTCTTTGGGACGCATGCTGCTTGATATCCTCAAATTC
CTCTTTATCTACTGCCTGGTACTACTAGCTTTTGCCAATGGACTGAACCAGCTTTACTTC
TATTATGAAACCAGAGCTATCGATGAGCCTAACAACTGCAAGGGGATCCGATGTGAGAAA
CAGAACAATGCCTTCTCCACGCTCTTTGAGACTCTTCAGTCACTCTTCTGGTCTGTATTT
GGCCTTTTAAATCTATATGTCACCAATGTGAAAGCCAGACACGAATTCACCGAGTTTGTA
GGAGCTACCATGTTTGGAACATACAATGTCATCTCCCTGGTAGTGCTGCTGAACATGCTG
ATTGCTATGATGAACAACTCCTATCAGCTTATTGCCGATCATGCTGATATCGAGTGGAAG
TTTGCAAGGACGAAGCTCTGGATGAGTTACTTTGATGAAGGTGGCACCTTGCCACCTCCT
TTCAACATCATCCCCAGCCCCAAGTCATTTCTATACCTTGGTAACTGGTTCAACAACACC
TTCTGCCCCAAAAGAGACCCTGACGGTAGACGGAGAAGGCGCAACTTGAGAAGTTTCACA
GAACGCAATGCTGACAGCCTGATACAAAATCAACATTATCAGGAAGTTATCAGGAATTTA
GTCAAAAGATATGTGGCTGCTATGATAAGAAATTCCAAAACACATGAGGGACTTACAGAA
GAAAATTTTAAGGAATTAAAGCAAGACATCTCCAGCTTTCGGTATGAAGTGCTTGACCTC
TTGGGAAATAGAAAACATCCAAGGAGCTTTTCCACTAGCAGCACTGAACTGTCTCAGAGA
GACGATAATAATGATGGCAGTGGTGGGGCTCGGGCCAAATCCAAGAGTGTCTCTTTTAAT
TTAGGCTGCAAGAAAAAGACTTGCCATGGGCCACCTCTCATCAGAACCATGCCAAGGTCC
AGTGGTGCCCAAGGAAAGTCAAAAGCTGAGTCATCAAGCAAACGCTCCTTCATGGGTCCT
TCTCTCAAGAAACTGGGTCTCCTATTCTCCAAATTTAATGGTCATATGTCTGAACCCAGT
TCAGAGCCAATGTACACAATTTCTGATGGAATTGTTCAGCAGCACTGTATGTGGCAGGAC
ATCAGATATTCTCAGATGGAGAAAGGGAAAGCAGAGGCCTGTTCTCAAAGTGAAATTAAC
CTCAGTGAGGTAGAATTAGGTGAAGTCCAGGGCGCTGCTCAGAGCAGTGAATGCCCTCTA
GCCTGTTCCAGCTCTCTTCACTGTGCATCCAGCATCTGCTCCTCAAATTCTAAACTTTTA
GACTCCTCAGAGGATGTATTTGAAACTTGGGGAGAGGCTTGTGACTTGCTCATGCACAAA
TGGGGTGATGGACAGGAAGAACAAGTTACAACTCGCCTCTAA
Protein Properties
Number of Residues 973
Molecular Weight 111411.0
Theoretical pI 7.31
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["331-351", "399-419", "438-458", "471-491", "513-533", "604-624"]
Protein Sequence 
>Short transient receptor potential channel 5
MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYN
VNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRR
PSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVE
CVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAE
YEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKE
FVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFI
KKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIK
EMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEA
LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF
YYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFV
GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPP
FNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNL
VKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRSFSTSSTELSQR
DDNNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSSGAQGKSKAESSSKRSFMGP
SLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQMEKGKAEACSQSEIN
LSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHK
WGDGQEEQVTTRL
GenBank ID Protein 6002474
UniProtKB/Swiss-Prot ID Q9UL62
UniProtKB/Swiss-Prot Entry Name TRPC5_HUMAN
PDB IDs Not Available
GenBank Gene ID AF054568
GeneCard ID TRPC5
GenAtlas ID TRPC5
HGNC ID HGNC:12337
References
General References Not Available