Cannabis Compound Database: Showing Protein Tropomyosin beta chain (CDBP03285)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03285

Secondary Accession Numbers

Not Available

Name

Tropomyosin beta chain

Description

Not Available

Synonyms

Beta-tropomyosin
Tropomyosin-2

Gene Name

TPM2

Protein Type

Enzyme

Biological Properties

General Function

Cell cycle control, cell division, chromosome partitioning

Specific Function

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments

GO Classification

Not Available

Cellular Location

Cytoplasm
cytoskeleton

Pathways

Name	SMPDB/Pathwhiz	KEGG
Muscle/Heart Contraction		Not Available
Acebutolol Action Pathway		Not Available
Alprenolol Action Pathway		Not Available
Atenolol Action Pathway		Not Available
Betaxolol Action Pathway		Not Available

Gene Properties

Chromosome Location

Chromosome:9

Locus

9p13

SNPs

TPM2

Gene Sequence

>855 bp
ATGGACGCCATCAAGAAGAAGATGCAGATGCTGAAGCTGGACAAGGAGAACGCCATCGAC
CGCGCCGAGCAGGCCGAAGCCGACAAGAAGCAAGCTGAGGACCGCTGCAAGCAGCTGGAG
GAGGAGCAGCAGGCCCTCCAGAAGAAGCTGAAGGGGACAGAGGATGAGGTGGAAAAGTAT
TCTGAATCCGTGAAGGAGGCCCAGGAGAAACTGGAGCAGGCCGAGAAGAAGGCCACTGAT
GCTGAGGCAGATGTGGCCTCCCTGAACCGCCGCATTCAGCTGGTTGAGGAGGAGCTGGAC
CGGGCCCAGGAGCGCCTGGCTACAGCCCTGCAGAAGCTGGAGGAGGCCGAGAAGGCGGCT
GATGAGAGCGAGAGAGGAATGAAGGTCATCGAAAACCGGGCCATGAAGGATGAGGAGAAG
ATGGAACTGCAGGAGATGCAGCTGAAGGAGGCCAAGCACATCGCTGAGGATTCAGACCGC
AAATATGAAGAGGTGGCCAGGAAGCTGGTGATCCTGGAAGGAGAGCTGGAGCGCTCGGAG
GAGAGGGCTGAGGTGGCCGAGAGTAAATGTGGGGACCTAGAGGAGGAGCTGAAAATTGTT
ACCAACAACTTGAAATCCCTGGAGGCCCAGGCGGACAAGTATTCCACCAAAGAAGATAAA
TATGAAGAGGAGATCAAACTGTTGGAGGAGAAGCTGAAGGAGGCTGAGACCCGAGCAGAG
TTTGCCGAGAGGTCTGTGGCAAAGTTGGAGAAAACCATCGATGACCTAGAAGATGAAGTC
TATGCCCAGAAGATGAAGTACAAGGCCATTAGCGAGGAACTGGACAACGCACTCAATGAC
ATCACCTCCCTCTGA

Protein Properties

Number of Residues

284

Molecular Weight

32850.4

Theoretical pI

4.36

Pfam Domain Function

Tropomyosin (PF00261 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Tropomyosin beta chain
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY
SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE
ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE
FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL

External Links

GenBank ID Protein

42476296

UniProtKB/Swiss-Prot ID

P07951

UniProtKB/Swiss-Prot Entry Name

TPM2_HUMAN

PDB IDs