| Identification |
|---|
| HMDB Protein ID
| CDBP03274 |
| Secondary Accession Numbers
| Not Available |
| Name
| Troponin I, fast skeletal muscle |
| Description
| Not Available |
| Synonyms
|
- Troponin I, fast-twitch isoform
|
| Gene Name
| TNNI2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in actin binding |
| Specific Function
| Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Muscle/Heart Contraction |    | Not Available | | Acebutolol Action Pathway |    | Not Available | | Alprenolol Action Pathway |    | Not Available | | Atenolol Action Pathway |    | Not Available | | Betaxolol Action Pathway |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p15.5 |
| SNPs
| TNNI2 |
| Gene Sequence
|
>549 bp
ATGGGAGATGAGGAGAAGCGGAACAGGGCCATCACGGCCCGCAGGCAGCACCTGAAGAGT
GTGATGCTGCAGATAGCGGCCACGGAGCTGGAGAAGGAGGAGAGCCGCCGTGAGGCAGAG
AAGCAGAACTACCTGGCGGAGCACTGCCCGCCGCTGCATATCCCGGGCTCCATGTCTGAA
GTGCAGGAGCTCTGCAAACAGCTGCACGCCAAGATCGATGCGGCTGAAGAGGAGAAGTAC
GACATGGAGGTGAGGGTGCAGAAGACCAGCAAGGAGCTGGAGGACATGAACCAGAAGCTA
TTTGATCTGCGGGGCAAGTTCAAGCGGCCCCCACTGCGGAGGGTGCGCATGTCGGCCGAT
GCCATGCTCAAGGCCCTGCTGGGCTCGAAGCACAAGGTGTGCATGGACCTGAGGGCCAAC
CTGAAGCAGGTCAAGAAGGAGGACACAGAGAAGGAGCGGGACCTGCGAGACGTGGGTGAC
TGGAGGAAGAACATCGAGGAGAAGTCTGGCATGGAGGGCCGGAAGAAGATGTTTGAGTCC
GAGTCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 182 |
| Molecular Weight
| 21338.4 |
| Theoretical pI
| 9.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Troponin I, fast skeletal muscle
MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
ES
|
| External Links |
|---|
| GenBank ID Protein
| 224967057 |
| UniProtKB/Swiss-Prot ID
| P48788 |
| UniProtKB/Swiss-Prot Entry Name
| TNNI2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001145829.1 |
| GeneCard ID
| TNNI2 |
| GenAtlas ID
| TNNI2 |
| HGNC ID
| HGNC:11946 |
| References |
|---|
| General References
| Not Available |