| Identification |
|---|
| HMDB Protein ID
| CDBP03273 |
| Secondary Accession Numbers
| Not Available |
| Name
| Troponin I, slow skeletal muscle |
| Description
| Not Available |
| Synonyms
|
- Troponin I, slow-twitch isoform
|
| Gene Name
| TNNI1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in actin binding |
| Specific Function
| Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Muscle/Heart Contraction |    | Not Available | | Acebutolol Action Pathway |    | Not Available | | Alprenolol Action Pathway |    | Not Available | | Atenolol Action Pathway |    | Not Available | | Betaxolol Action Pathway |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q31.3 |
| SNPs
| TNNI1 |
| Gene Sequence
|
>564 bp
ATGCCGGAAGTCGAGAGAAAACCCAAGATCACTGCCTCCCGCAAACTCTTGCTGAAGAGC
CTGATGCTGGCCAAGGCCAAGGAATGCTGGGAGCAGGAGCACGAGGAGCGCGAGGCTGAG
AAGGTGCGCTACCTGGCAGAGCGCATCCCCACGCTGCAGACCCGTGGCCTGTCCCTCAGT
GCCCTGCAGGACCTGTGCCGGGAGCTGCACGCCAAGGTGGAGGTGGTGGATGAGGAGCGA
TACGACATTGAGGCCAAATGCCTCCACAACACCAGGGAGATTAAGGACCTGAAGCTGAAG
GTGATGGACCTCCGTGGGAAGTTCAAGCGCCCGCCCCTGCGTCGAGTCCGTGTCTCGGCT
GACGCCATGCTCCGGGCCCTGCTGGGCTCCAAGCACAAGGTGTCCATGGATCTGCGGGCC
AACCTCAAGTCTGTGAAGAAGGAAGACACAGAGAAGGAGCGGCCTGTGGAGGTGGGTGAC
TGGAGGAAGAACGTGGAGGCCATGTCTGGCATGGAAGGCCGGAAGAAGATGTTTGATGCC
GCCAAGTCTCCGACCTCACAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 187 |
| Molecular Weight
| 21692.1 |
| Theoretical pI
| 10.3 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Troponin I, slow skeletal muscle
MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSA
DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDA
AKSPTSQ
|
| External Links |
|---|
| GenBank ID Protein
| 56682969 |
| UniProtKB/Swiss-Prot ID
| P19237 |
| UniProtKB/Swiss-Prot Entry Name
| TNNI1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_003281.3 |
| GeneCard ID
| TNNI1 |
| GenAtlas ID
| TNNI1 |
| HGNC ID
| HGNC:11945 |
| References |
|---|
| General References
| Not Available |