Showing Protein Trimeric intracellular cation channel type B (CDBP03270)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03270
Secondary Accession Numbers Not Available
Name Trimeric intracellular cation channel type B
Description Not Available
Synonyms
  1. TRIC-B
  2. TRICB
  3. Transmembrane protein 38B
Gene Name TMEM38B
Protein Type Transporter
Biological Properties
General Function Involved in cation channel activity
Specific Function Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores
GO Classification
Component
membrane
cell part
Function
ion channel activity
cation channel activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
Process
establishment of localization
transport
monovalent inorganic cation transport
ion transport
cation transport
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9q31.2
SNPs TMEM38B
Gene Sequence 
>876 bp
ATGGATTCTCCATGGGACGAGTTGGCTCTGGCCTTCTCCCGCACGTCCATGTTTCCCTTT
TTTGACATCGCGCACTATCTAGTGTCAGTGATGGCGGTGAAACGTCAGCCGGGAGCAGCT
GCATTGGCATGGAAGAATCCTATTTCAAGCTGGTTTACTGCTATGCTCCACTGTTTTGGT
GGAGGAATTTTATCCTGTCTACTGCTTGCAGAGCCTCCATTGAAGTTTCTTGCAAACCAC
ACTAACATATTACTGGCATCTTCAATCTGGTATATTACATTTTTTTGCCCGCATGACCTA
GTTTCCCAGGGCTATTCATATCTACCTGTTCAACTACTGGCTTCGGGAATGAAGGAAGTG
ACCAGAACTTGGAAAATAGTAGGTGGAGTCACACATGCTAATAGCTATTACAAAAATGGC
TGGATAGTCATGATAGCTATTGGATGGGCCCGAGGTGCAGGTGGTACCATTATAACGAAT
TTTGAGAGGTTGGTAAAAGGAGATTGGAAACCAGAAGGTGATGAATGGCTGAAGATGTCA
TACCCTGCCAAGGTAACCCTGCTGGGGTCAGTTATCTTCACATTCCAGCACACCCAGCAT
CTGGCAATATCAAAGCATAATCTTATGTTCCTTTATACCATCTTTATTGTGGCCACAAAG
ATAACCATGATGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATACATTG
AGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCA
AAGTCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGAT
AATGTTAAAAAGAAACATACTAAGAAGAATGAATAA
Protein Properties
Number of Residues 291
Molecular Weight 32509.6
Theoretical pI 9.48
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["50-70", "76-96", "141-161", "208-228"]
Protein Sequence 
>Trimeric intracellular cation channel type B
MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
GenBank ID Protein 7022563
UniProtKB/Swiss-Prot ID Q9NVV0
UniProtKB/Swiss-Prot Entry Name TM38B_HUMAN
PDB IDs Not Available
GenBank Gene ID AK001355
GeneCard ID TMEM38B
GenAtlas ID TMEM38B
HGNC ID HGNC:25535
References
General References Not Available