Showing Protein Trimeric intracellular cation channel type A (CDBP03269)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03269
Secondary Accession Numbers Not Available
Name Trimeric intracellular cation channel type A
Description Not Available
Synonyms
  1. TRIC-A
  2. TRICA
  3. Transmembrane protein 38A
Gene Name TMEM38A
Protein Type Transporter
Biological Properties
General Function Involved in cation channel activity
Specific Function Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores
GO Classification
Component
membrane
cell part
Function
transporter activity
ion channel activity
cation channel activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
Process
establishment of localization
transport
monovalent inorganic cation transport
ion transport
cation transport
Cellular Location
  1. Multi-pass membrane protein
  2. Sarcoplasmic reticulum membrane
  3. Nucleus membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19p13.11
SNPs TMEM38A
Gene Sequence 
>900 bp
ATGGAGCTGCTCTCGGCGCTGAGCCTGGGCGAACTGGCGCTCAGCTTCTCGCGGGTGCCG
CTCTTCCCCGTCTTCGACCTCAGTTACTTCATCGTCTCCATCCTCTACCTCAAGTATGAG
CCAGGAGCAGTCGAACTGTCCCGGCGCCACCCCATCGCGTCCTGGCTGTGCGCCATGCTG
CATTGCTTCGGGAGCTACATCCTGGCTGATCTGCTCCTTGGGGAGCCACTGATCGATTAC
TTCAGCAACAACTCCAGCATCCTGCTGGCCTCAGCTGTCTGGTACTTGATTTTCTTCTGC
CCCCTGGACCTCTTCTACAAGTGTGTCTGCTTCCTGCCTGTGAAACTCATCTTCGTGGCC
ATGAAGGAGGTGGTGCGAGTCCGCAAGATCGCGGTGGGCATCCATCACGCCCATCACCAC
TACCACCACGGGTGGTTCGTCATGATTGCAACTGGGTGGGTCAAAGGTTCTGGTGTCGCC
CTCATGTCCAACTTTGAGCAGCTGCTCCGAGGGGTCTGGAAGCCAGAGACCAACGAGATC
CTGCACATGTCTTTCCCCACCAAGGCCAGCCTGTATGGAGCCATCCTCTTCACCCTCCAG
CAGACCCGCTGGCTCCCAGTGTCCAAAGCCAGCCTCATCTTCATCTTCACCTTGTTCATG
GTGTCCTGTAAGGTGTTTCTGACAGCCACCCACTCACACAGCTCCCCCTTTGATGCCCTG
GAGGGCTACATCTGCCCCGTGCTGTTTGGTTCGGCCTGCGGGGGTGACCATCACCACGAC
AACCATGGTGGGTCCCACAGCGGTGGTGGGCCAGGAGCTCAGCATTCGGCCATGCCCGCC
AAGTCCAAGGAGGAGTTGAGCGAGGGCTCCAGGAAGAAGAAGGCCAAGAAGGCGGATTAG
Protein Properties
Number of Residues 299
Molecular Weight 33259.6
Theoretical pI 8.41
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["52-72", "86-106", "145-165", "210-230"]
Protein Sequence 
>Trimeric intracellular cation channel type A
MELLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPIASWLCAML
HCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVA
MKEVVRVRKIAVGIHHAHHHYHHGWFVMIATGWVKGSGVALMSNFEQLLRGVWKPETNEI
LHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTLFMVSCKVFLTATHSHSSPFDAL
EGYICPVLFGSACGGDHHHDNHGGSHSGGGPGAQHSAMPAKSKEELSEGSRKKKAKKAD
GenBank ID Protein 10438670
UniProtKB/Swiss-Prot ID Q9H6F2
UniProtKB/Swiss-Prot Entry Name TM38A_HUMAN
PDB IDs Not Available
GenBank Gene ID AK025981
GeneCard ID TMEM38A
GenAtlas ID TMEM38A
HGNC ID HGNC:28462
References
General References Not Available