Showing Protein Tuberoinfundibular peptide of 39 residues (CDBP03268)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03268
Secondary Accession Numbers Not Available
Name Tuberoinfundibular peptide of 39 residues
Description Not Available
Synonyms
  1. Parathyroid hormone 2
  2. TIP39
Gene Name PTH2
Protein Type Enzyme
Biological Properties
General Function Involved in neuropeptide signaling pathway
Specific Function Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits
GO Classification Not Available
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.33
SNPs PTH2
Gene Sequence 
>303 bp
ATGGAGACCCGCCAGGTGTCCAGGAGCCCTCGGGTTCGGCTGCTGCTGCTGCTGCTGCTG
CTGCTGGTGGTGCCCTGGGGCGTCCGCACTGCCTCGGGAGTCGCCCTGCCCCCGGTCGGG
GTCCTCAGCCTCCGCCCCCCAGGACGGGCCTGGGCGGATCCCGCCACCCCCAGGCCGCGG
AGGAGCCTGGCGCTGGCGGACGACGCGGCCTTCCGGGAACGCGCGCGGTTGCTGGCCGCC
CTCGAGCGCCGCCACTGGCTGAACTCGTACATGCACAAGCTGCTGGTGTTGGATGCGCCC
TGA
Protein Properties
Number of Residues 100
Molecular Weight 11202.1
Theoretical pI 12.33
Pfam Domain Function Not Available
Signals
  • ["1-30"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Tuberoinfundibular peptide of 39 residues
METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPR
RSLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q96A98
UniProtKB/Swiss-Prot Entry Name TIP39_HUMAN
PDB IDs Not Available
GenBank Gene ID AY037555
GeneCard ID PTH2
GenAtlas ID PTH2
HGNC ID HGNC:30828
References
General References Not Available