| Identification |
|---|
| HMDB Protein ID
| CDBP03266 |
| Secondary Accession Numbers
| Not Available |
| Name
| Trefoil factor 1 |
| Description
| Not Available |
| Synonyms
|
- Breast cancer estrogen-inducible protein
- PNR-2
- Polypeptide P1.A
- Protein pS2
- hP1.A
|
| Gene Name
| TFF1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in growth factor activity |
| Specific Function
| Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 21q22.3 |
| SNPs
| TFF1 |
| Gene Sequence
|
>255 bp
ATGGCCACCATGGAGAACAAGGTGATCTGCGCCCTGGTCCTGGTGTCCATGCTGGCCCTC
GGCACCCTGGCCGAGGCCCAGACAGAGACGTGTACAGTGGCCCCCCGTGAAAGACAGAAT
TGTGGTTTTCCTGGTGTCACGCCCTCCCAGTGTGCAAATAAGGGCTGCTGTTTCGACGAC
ACCGTTCGTGGGGTCCCCTGGTGCTTCTATCCTAATACCATCGACGTCCCTCCAGAAGAG
GAGTGTGAATTTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 84 |
| Molecular Weight
| 9149.4 |
| Theoretical pI
| 4.01 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Trefoil factor 1
MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDD
TVRGVPWCFYPNTIDVPPEEECEF
|
| External Links |
|---|
| GenBank ID Protein
| 10280534 |
| UniProtKB/Swiss-Prot ID
| P04155 |
| UniProtKB/Swiss-Prot Entry Name
| TFF1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AB038162 |
| GeneCard ID
| TFF1 |
| GenAtlas ID
| TFF1 |
| HGNC ID
| HGNC:11755 |
| References |
|---|
| General References
| Not Available |