| Identification |
|---|
| HMDB Protein ID
| CDBP03259 |
| Secondary Accession Numbers
| Not Available |
| Name
| Transgelin |
| Description
| Not Available |
| Synonyms
|
- 22 kDa actin-binding protein
- Protein WS3-10
- SM22-alpha
- Smooth muscle protein 22-alpha
|
| Gene Name
| TAGLN |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in muscle organ development |
| Specific Function
| Actin cross-linking/gelling protein. Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence |
| GO Classification
|
| Process |
| muscle organ development |
| developmental process |
| anatomical structure development |
| organ development |
|
| Cellular Location
|
- Cytoplasm (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q23.2 |
| SNPs
| TAGLN |
| Gene Sequence
|
>606 bp
ATGGCCAACAAGGGTCCTTCCTATGGCATGAGCCGCGAAGTGCAGTCCAAAATCGAGAAG
AAGTATGACGAGGAGCTGGAGGAGCGGCTGGTGGAGTGGATCATAGTGCAGTGTGGCCCT
GATGTGGGCCGCCCAGACCGTGGGCGCTTGGGCTTCCAGGTCTGGCTGAAGAATGGCGTG
ATTCTGAGCAAGCTGGTGAACAGCCTGTACCCTGATGGCTCCAAGCCGGTGAAGGTGCCC
GAGAACCCACCCTCCATGGTCTTCAAGCAGATGGAGCAGGTGGCTCAGTTCCTGAAGGCG
GCTGAGGACTATGGGGTCATCAAGACTGACATGTTCCAGACTGTTGACCTCTTTGAAGGC
AAAGACATGGCAGCAGTGCAGAGGACCCTGATGGCTTTGGGCAGCTTGGCAGTGACCAAG
AATGATGGGCACTACCGTGGAGATCCCAACTGGTTTATGAAGAAAGCGCAGGAGCATAAG
AGGGAATTCACAGAGAGCCAGCTGCAGGAGGGAAAGCATGTCATTGGCCTTCAGATGGGC
AGCAACAGAGGGGCCTCCCAGGCCGGCATGACAGGCTACGGACGACCTCGGCAGATCATC
AGTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 201 |
| Molecular Weight
| 22610.8 |
| Theoretical pI
| 9.29 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Transgelin
MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
SNRGASQAGMTGYGRPRQIIS
|
| External Links |
|---|
| GenBank ID Protein
| 2501855 |
| UniProtKB/Swiss-Prot ID
| Q01995 |
| UniProtKB/Swiss-Prot Entry Name
| TAGL_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF013711 |
| GeneCard ID
| TAGLN |
| GenAtlas ID
| TAGLN |
| HGNC ID
| HGNC:11553 |
| References |
|---|
| General References
| Not Available |