| Identification |
|---|
| HMDB Protein ID
| CDBP03253 |
| Secondary Accession Numbers
| Not Available |
| Name
| Taste receptor type 2 member 16 |
| Description
| Not Available |
| Synonyms
|
- T2R16
|
| Gene Name
| TAS2R16 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor activity |
| Specific Function
| Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 |
| GO Classification
|
| Component |
| intrinsic to membrane |
| integral to membrane |
| cell part |
| membrane part |
| Function |
| receptor activity |
| transmembrane receptor activity |
| molecular transducer activity |
| signal transducer activity |
| g-protein coupled receptor activity |
| Process |
| g-protein coupled receptor protein signaling pathway |
| multicellular organismal process |
| system process |
| neurological system process |
| sensory perception |
| sensory perception of chemical stimulus |
| sensory perception of taste |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q31.1-q31.3|7q31 |
| SNPs
| TAS2R16 |
| Gene Sequence
|
>876 bp
ATGATACCCATCCAACTCACTGTCTTCTTCATGATCATCTATGTGCTTGAGTCCTTGACA
ATTATTGTGCAGAGCAGCCTAATTGTTGCAGTGCTGGGCAGAGAATGGCTGCAAGTCAGA
AGGCTGATGCCTGTGGACATGATTCTCATCAGCCTGGGCATCTCTCGCTTCTGTCTACAG
TGGGCATCAATGCTGAACAATTTTTGCTCCTATTTTAATTTGAATTATGTACTTTGCAAC
TTAACAATCACCTGGGAATTTTTTAATATCCTTACATTCTGGTTAAACAGCTTGCTTACC
GTGTTCTACTGCATCAAGGTCTCTTCTTTCACCCATCACATCTTTCTCTGGCTGAGGTGG
AGAATTTTGAGGTTGTTTCCCTGGATATTACTGGGTTCTCTGATGATTACTTGTGTAACA
ATCATCCCTTCAGCTATTGGGAATTACATTCAAATTCAGTTACTCACCATGGAGCATCTA
CCAAGAAACAGCACTGTAACTGACAAACTTGAAAATTTTCATCAGTATCAGTTCCAGGCT
CATACAGTTGCATTGGTTATTCCTTTCATCCTGTTCCTGGCCTCCACCATCTTTCTCATG
GCATCACTGACCAAGCAGATACAACATCATAGCACTGGTCACTGCAATCCAAGCATGAAA
GCGCGCTTCACTGCCCTGAGGTCCCTTGCCGTCTTATTTATTGTGTTTACCTCTTACTTT
CTAACCATACTCATCACCATTATAGGTACTCTATTTGATAAGAGATGTTGGTTATGGGTC
TGGGAAGCTTTTGTCTATGCTTTCATCTTAATGCATTCCACTTCACTGATGCTGAGCAGC
CCTACGTTGAAAAGGATTCTAAAGGGAAAGTGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 291 |
| Molecular Weight
| 33985.5 |
| Theoretical pI
| 9.65 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["2-22", "42-62", "85-105", "126-146", "183-203", "229-249", "258-278"]
|
| Protein Sequence
|
>Taste receptor type 2 member 16
MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQ
WASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRW
RILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQA
HTVALVIPFILFLASTIFLMASLTKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYF
LTILITIIGTLFDKRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
|
| External Links |
|---|
| GenBank ID Protein
| 30142034 |
| UniProtKB/Swiss-Prot ID
| Q9NYV7 |
| UniProtKB/Swiss-Prot Entry Name
| T2R16_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC004838 |
| GeneCard ID
| TAS2R16 |
| GenAtlas ID
| TAS2R16 |
| HGNC ID
| HGNC:14921 |
| References |
|---|
| General References
| Not Available |