| Identification |
| HMDB Protein ID
| CDBP03250 |
| Secondary Accession Numbers
| Not Available |
| Name
| Synaptotagmin-like protein 3 |
| Description
| Not Available |
| Synonyms
|
- Exophilin-6
|
| Gene Name
| SYTL3 |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in Rab GTPase binding |
| Specific Function
| May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions |
| GO Classification
|
| Function |
| small gtpase regulator activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
| enzyme regulator activity |
| rab gtpase binding |
| nucleoside-triphosphatase regulator activity |
| gtpase regulator activity |
| Process |
| transport |
| protein transport |
| intracellular protein transport |
| establishment of localization |
|
| Cellular Location
|
- Endomembrane system
- Peripheral membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:6 |
| Locus
| 6q25.3 |
| SNPs
| SYTL3 |
| Gene Sequence
|
>1833 bp
ATGGCCCAAGAAATAGATCTGAGTGCTCTCAAGGAGTTAGAACGCGAGGCCATTCTCCAG
GTCCTGTACCGAGACCAGGCGGTTCAAAACACAGAGGAGGAGAGGACACGGAAACTGAAA
ACACACCTGCAGCATCTCCGGTGGAAAGGAGCGAAGAACACGGACTGGGAGCACAAAGAG
AAGTGCTGTGCGCGCTGCCAGCAGGTGCTGGGGTTCCTGCTGCACCGGGGCGCCGTGTGC
CGGGGCTGCAGCCACCGCGTGTGTGCCCAGTGCCGAGTGTTCCTGAGGGGGACCCATGCC
TGGAAGTGCACGGTGTGCTTCGAGGACAGGAATGTCAAAATAAAAACTGGAGAATGGTTC
TATGAGGAACGAGCCAAGAAATTTCCAACTGGAGGCAAACATGAGACAGTTGGAGGGCAG
CTCTTGCAATCTTATCAGAAGCTGAGCAAAATTTCTGTGGTTCCTCCTACTCCACCTCCT
GTCAGCGAGAGCCAGTGCAGCCGCAGTCCTGGCAGGTTACAGGAATTTGGTCAGTTTAGA
GGATTTAATAAGTCCGTGGAAAATTTGTTTCTGTCTCTTGCTACCCACGTGAAAAAGCTC
TCCAAATCCCAGAATGATATGACTTCTGAGAAGCATCTTCTCGCCACGGGCCCCAGGCAG
TGTGTGGGACAGACAGAGAGACGGAGCCAGTCTGACACTGCGGTCAACGTCACCACCAGG
AAGGTCAGTGCACCAGATATTCTGAAACCTCTCAATCAAGAGGATCCCAAATGCTCTACT
AACCCTATTTTGAAGCAACAGAATCTCCCATCCAGTCCGGCACCCAGTACCATATTCTCT
GGAGGTTTTAGACACGGAAGTTTAATTAGCATTGACAGCACCTGTACAGAGATGGGCAAT
TTTGACAATGCTAATGTCACTGGAGAAATAGAATTTGCCATTCATTATTGCTTCAAAACC
CATTCTTTAGAAATATGCATCAAGGCCTGTAAGAACCTTGCCTATGGAGAAGAAAAGAAG
AAAAAGTGCAATCCGTATGTGAAGACCTACCTGTTGCCCGACAGATCCTCCCAGGGAAAG
CGCAAGACTGGAGTCCAAAGGAACACCGTGGACCCGACCTTTCAGGAGACCTTGAAGTAT
CAGGTGGCCCCTGCCCAGCTGGTGACCCGGCAGCTGCAGGTCTCGGTGTGGCATCTGGGC
ACGCTGGCCCGGAGAGTGTTTCTTGGAGAAGTGATCATTCCTCTGGCCACGTGGGACTTT
GAAGACAGCACAACACAGTCCTTCCGCTGGCATCCGCTCCGGGCCAAGGCGGAGAAATAC
GAAGACAGCGTTCCTCAGAGTAATGGAGAGCTCACAGTCCGGGCTAAGCTGGTTCTCCCT
TCACGGCCCAGAAAACTCCAAGAGGCTCAAGAAGGGACAGATCAGCCATCACTTCATGGT
CAACTTTGTTTGGTAGTGCTAGGAGCCAAGAATTTACCTGTGCGGCCAGATGGCACCTTG
AACTCATTTGTTAAGGGCTGTCTCACTCTGCCAGACCAACAAAAACTGAGACTGAAGTCG
CCAGTCCTGAGGAAGCAGGCTTGCCCCCAGTGGAAACACTCATTTGTCTTCAGTGGCGTA
ACCCCAGCTCAGCTGAGGCAGTCAAGCTTGGAGTTAACTGTCTGGGATCAGGCCCTCTTT
GGAATGAACGACCGCTTGCTTGGAGGAACCAGACTTGGTTCAAAGGGAGACACAGCTGTT
GGCGGGGATGCATGCTCACTATCGAAGCTCCAGTGGCAGAAAGTCCTTTCCAGCCCCAAT
CTATGGACAGACATGACTCTTGTCCTGCACTGA
|
| Protein Properties |
| Number of Residues
| 610 |
| Molecular Weight
| 68559.1 |
| Theoretical pI
| 9.78 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Synaptotagmin-like protein 3
MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE
KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF
YEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRLQEFGQFR
GFNKSVENLFLSLATHVKKLSKSQNDMTSEKHLLATGPRQCVGQTERRSQSDTAVNVTTR
KVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGN
FDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGK
RKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDF
EDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHG
QLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGV
TPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPN
LWTDMTLVLH
|
| External Links |
| GenBank ID Protein
| 66347777 |
| UniProtKB/Swiss-Prot ID
| Q4VX76 |
| UniProtKB/Swiss-Prot Entry Name
| SYTL3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AL589931 |
| GeneCard ID
| SYTL3 |
| GenAtlas ID
| SYTL3 |
| HGNC ID
| HGNC:15587 |
| References |
| General References
| Not Available |