| Identification |
|---|
| HMDB Protein ID
| CDBP03240 |
| Secondary Accession Numbers
| Not Available |
| Name
| Synaptotagmin-11 |
| Description
| Not Available |
| Synonyms
|
- Synaptotagmin XI
- SytXI
|
| Gene Name
| SYT11 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in transporter activity |
| Specific Function
| May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis |
| GO Classification
|
| Component |
| coated vesicle |
| clathrin-coated vesicle |
| synaptic vesicle |
| membrane |
| cell part |
| organelle |
| vesicle |
| cytoplasmic vesicle |
| cytoplasmic membrane-bounded vesicle |
| Function |
| transporter activity |
| Process |
| establishment of localization |
| transport |
|
| Cellular Location
|
- Cytoplasmic vesicle
- Membrane
- Single-pass membrane protein
- Single-pass membrane protein
- secretory vesicle
- Cell junction
- synapse
- synaptic vesicle membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21.2 |
| SNPs
| SYT11 |
| Gene Sequence
|
>1296 bp
ATGGCTGAGATCACCAATATCCGACCTAGCTTTGATGTGTCACCGGTGGTGGCCGGCCTC
ATCGGGGCCTCTGTGCTGGTGGTGTGTGTCTCGGTGACCGTCTTTGTCTGGTCATGCTGC
CACCAGCAGGCAGAGAAGAAGCACAAGAGCCCACCATACAAGTTTATTCACATGCTCAAA
GGCATCAGCATATACCCAGAGACCCTCAGCAACAAGAAGAAAATCATCAAAGTGCGGAGA
GACAAAGATGGTCCTGGGAGGGAAGGTGGACGTAGGAACCTGTTGGTGGACGCAGCAGAG
GCTGGCCTGCTAAGCCGAGACAAAGATCCCAGGGGGCCTAGCTCTGGATCTTGTATAGAC
CAATTACCCATCAAAATGGACTATGGGGAAGAACTAAGGAGCCCTATTACAAGCCTGACC
CCTGGGGAGAGCAAAACCACCTCTCCATCATCTCCAGAGGAGGATGTCATGCTAGGATCC
CTCACCTTCTCAGTGGACTATAACTTCCCGAAAAAAGCCCTGGTGGTGACAATCCAGGAG
GCCCACGGGCTGCCAGTGATGGATGACCAGACCCAGGGATCTGACCCCTACATCAAAATG
ACCATCCTTCCTGACAAACGGCATCGGGTGAAGACCAGAGTGCTGCGGAAGACCCTGGAC
CCTGTGTTTGACGAGACCTTCACCTTCTATGGCATCCCCTACAGCCAGCTGCAGGACCTG
GTGCTGCACTTCCTTGTCCTCAGCTTTGACCGCTTCTCTCGGGATGATGTCATTGGCGAG
GTCATGGTGCCACTGGCAGGGGCGGACCCCAGCACAGGCAAGGTACAACTGACCAGGGAC
ATCATCAAAAGGAATATCCAGAAGTGCATCAGCAGAGGGGAGCTCCAGGTGTCTCTGTCA
TATCAGCCTGTGGCACAGAGAATGACAGTGGTGGTCCTCAAAGCCAGACACTTGCCGAAG
ATGGATATCACCGGTCTCTCAGGTAATCCTTATGTCAAGGTGAACGTCTACTACGGCAGA
AAGCGCATTGCCAAGAAGAAAACCCATGTGAAGAAGTGCACTTTGAACCCCATCTTCAAT
GAATCTTTCATCTACGACATCCCCACTGACCTCCTGCCTGATATCAGCATCGAGTTCCTC
GTTATCGACTTCGATCGCACCACCAAGAATGAGGTGGTGGGGAGGCTGATCCTGGGGGCA
CACAGTGTCACAGCCAGTGGTGCTGAACACTGGAGAGAGGTCTGCGAGAGCCCCCGCAAG
CCTGTGGCCAAGTGGCACAGTCTGAGCGAGTACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 431 |
| Molecular Weight
| 48296.5 |
| Theoretical pI
| 9.45 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Synaptotagmin-11
MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
PVAKWHSLSEY
|
| External Links |
|---|
| GenBank ID Protein
| 14042290 |
| UniProtKB/Swiss-Prot ID
| Q9BT88 |
| UniProtKB/Swiss-Prot Entry Name
| SYT11_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK027540 |
| GeneCard ID
| SYT11 |
| GenAtlas ID
| SYT11 |
| HGNC ID
| HGNC:19239 |
| References |
|---|
| General References
| Not Available |