| Identification |
|---|
| HMDB Protein ID
| CDBP03237 |
| Secondary Accession Numbers
| Not Available |
| Name
| Synapsin-3 |
| Description
| Not Available |
| Synonyms
|
- Synapsin III
|
| Gene Name
| SYN3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| May be involved in the regulation of neurotransmitter release and synaptogenesis |
| GO Classification
|
| Component |
| coated vesicle |
| clathrin-coated vesicle |
| synaptic vesicle |
| organelle |
| vesicle |
| cytoplasmic vesicle |
| cytoplasmic membrane-bounded vesicle |
| Function |
| binding |
| catalytic activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| Process |
| neurotransmitter secretion |
| biological regulation |
| regulation of biological quality |
| regulation of neurotransmitter levels |
|
| Cellular Location
|
- Peripheral membrane protein
- Cytoplasmic vesicle
- Cytoplasmic side
- secretory vesicle
- synaptic vesicle membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22q12.3 |
| SNPs
| SYN3 |
| Gene Sequence
|
>1743 bp
ATGAATTTCCTCCGGCGACGTCTCTCTGACAGCAGCTTCATGGCCAACCTGCCTAATGGC
TATATGACGGACCTGCAACGCCCAGATAGCTCCACCAGCTCACCTGCTTCCCCCGCCATG
GAGAGGAGGCACCCCCAGCCCCTGGCTGCCTCCTTCTCCTCTCCAGGATCCAGCCTTTTT
AGCTCCCTCTCCAGTGCCATGAAGCAGGCCCCTCAGGCCACCTCAGGACTGATGGAGCCT
CCAGGTCCCTCCACGCCCATTGTTCAAAGACCCAGGATCCTGTTGGTGATCGATGATGCC
CATACAGACTGGTCGAAGTATTTCCATGGGAAGAAGGTGAATGGAGAGATTGAGATCCGA
GTGGAGCAGGCTGAATTCTCAGAGTTGAACCTAGCTGCCTATGTGACCGGGGGCTGCATG
GTGGACATGCAGGTCGTGAGAAATGGGACCAAAGTGGTGAGCAGATCCTTCAAGCCAGAC
TTCATCCTGGTCCGCCAGCATGCCTACAGCATGGCCCTGGGGGAAGACTACCGCAGCCTG
GTCATCGGCCTGCAGTATGGAGGGCTGCCTGCTGTCAACTCTCTCTACTCCGTCTACAAC
TTCTGCAGCAAGCCCTGGGTGTTCTCTCAGCTCATTAAGATCTTCCATTCCCTGGGTCCT
GAGAAGTTCCCGCTTGTGGAGCAAACATTTTTCCCCAACCATAAGCCAATGGTCACAGCC
CCACACTTCCCGGTGGTAGTCAAGCTGGGACATGCCCACGCTGGAATGGGAAAGATCAAA
GTGGAAAACCAGCTTGACTTCCAGGACATCACCAGCGTGGTCGCCATGGCCAAAACATAC
GCCACCACCGAGGCGTTCATCGACTCCAAGTACGACATCCGCATCCAGAAAATTGGATCC
AACTACAAGGCTTACATGAGAACCTCCATCTCTGGGAACTGGAAGGCCAACACAGGCTCT
GCCATGCTGGAGCAGGTGGCCATGACAGAGAGGTACAGGCTGTGGGTGGACAGCTGCTCG
GAAATGTTTGGCGGCCTGGACATCTGTGCCGTCAAGGCTGTCCACAGCAAGGATGGCAGA
GATTACATCATCGAGGTAATGGACAGCTCAATGCCGCTGATTGGAGAGCATGTGGAAGAG
GACAGACAGCTGATGGCCGACCTTGTTGTCTCCAAAATGAGCCAGCTCCCGATGCCAGGA
GGCACAGCGCCCTCCCCCCTCAGACCTTGGGCTCCACAGATTAAATCAGCGAAATCCCCA
GGGCAAGCCCAGCTGGGGCCTCAGCTAGGCCAGCCCCAGCCACGCCCACCTCCGCAAGGA
GGCCCTCGCCAAGCTCAGTCTCCTCAGCCCCAGAGATCTGGAAGCCCCTCCCAACAGAGG
CTCTCCCCACAAGGCCAGCAGCCCCTGAGCCCCCAGTCCGGATCTCCACAGCAGCAAAGG
TCACCAGGCTCTCCGCAGCTATCCCGGGCATCCAGTGGCAGCTCCCCAAACCAGGCCTCC
AAGCCAGGTGCCACCCTCGCCTCACAGCCCCGGCCCCCTGTGCAGGGCCGTAGTACCTCC
CAGCAGGGTGAAGAGTCCAAGAAGCCAGCACCACCCCATCCGCATCTCAACAAATCTCAG
TCCCTGACTAACAGCCTCAGCACATCCGACACCTCCCAGCGTGGGACCCCAAGTGAAGAC
GAGGCCAAGGCTGAAACCATCCGCAACCTGAGGAAGTCTTTTGCCAGCCTGTTCTCTGAC
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 580 |
| Molecular Weight
| 63302.2 |
| Theoretical pI
| 9.86 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Synapsin-3
MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF
SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR
VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL
VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA
PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS
NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR
DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP
GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR
SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ
SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD
|
| External Links |
|---|
| GenBank ID Protein
| 3090889 |
| UniProtKB/Swiss-Prot ID
| O14994 |
| UniProtKB/Swiss-Prot Entry Name
| SYN3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF046873 |
| GeneCard ID
| SYN3 |
| GenAtlas ID
| SYN3 |
| HGNC ID
| HGNC:11496 |
| References |
|---|
| General References
| Not Available |