| Identification |
| HMDB Protein ID
| CDBP03235 |
| Secondary Accession Numbers
| Not Available |
| Name
| Synaptic vesicle glycoprotein 2B |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| SV2B |
| Protein Type
| Transporter |
| Biological Properties |
| General Function
| Involved in transmembrane transport |
| Specific Function
| Probably plays a role in the control of regulated secretion in neural and endocrine cells |
| GO Classification
|
| Component |
| membrane |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| transporter activity |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Cytoplasmic vesicle
- Cytoplasmic vesicle
- Multi-pass membrane protein
- secretory vesicle
- secretory vesicle
- acrosome
- synaptic vesicle membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 15q26.1 |
| SNPs
| SV2B |
| Gene Sequence
|
>2052 bp
ATGGATGACTACAAGTATCAGGACAATTATGGGGGCTATGCTCCCAGTGATGGCTATTAC
CGCGGCAATGAGTCCAACCCAGAAGAAGATGCACAGAGTGATGTCACCGAAGGCCATGAT
GAGGAAGACGAGATCTATGAGGGCGAGTACCAGGGTATCCCTCACCCAGATGATGTCAAG
GCCAAGCAGGCCAAGATGGCGCCCTCCAGAATGGACAGCCTTCGGGGCCAGACAGACCTG
ATGGCTGAGAGGCTGGAAGATGAGGAGCAGTTGGCCCACCAGTACGAGACCATCATGGAT
GAGTGTGGCCATGGCCGCTTCCAGTGGATCCTCTTTTTCGTCTTGGGTTTGGCCCTGATG
GCCGATGGGGTGGAAGTGTTCGTGGTGAGTTTTGCCCTGCCCAGTGCAGAGAAGGACATG
TGTCTGTCCAGTTCCAAAAAAGGAATGCTAGGGATGATAGTCTACTTGGGAATGATGGCG
GGCGCCTTCATCCTGGGAGGCCTGGCTGATAAGCTGGGAAGGAAGCGAGTCCTCAGCATG
TCTCTGGCCGTCAATGCCTCCTTCGCCTCCCTCTCTTCCTTCGTGCAGGGATATGGAGCC
TTCCTCTTCTGCCGACTCATCTCAGGCATCGGTATTGGGGGTGCTCTACCGATTGTTTTT
GCCTATTTTTCTGAATTCTTGTCTCGGGAGAAGCGAGGAGAACACCTCAGTTGGCTGGGC
ATCTTCTGGATGACTGGGGGCCTGTACGCATCTGCCATGGCCTGGAGCATCATCCCACAC
TATGGCTGGGGCTTCAGCATGGGGACCAATTACCACTTCCATAGCTGGAGAGTGTTTGTC
ATCGTCTGTGCTCTGCCCTGCACCGTGTCCATGGTGGCCCTGAAGTTCATGCCAGAGAGC
CCAAGGTTTCTGCTAGAGATGGGCAAACATGATGAAGCCTGGATGATTCTCAAGCAAGTC
CATGACACCAACATGAGAGCTAAGGGGACCCCAGAGAAAGTGTTCACGGTTTCCAACATC
AAAACTCCCAAGCAAATGGATGAATTCATTGAGATCCAAAGTTCAACAGGAACCTGGTAC
CAGCGCTGGCTGGTCAGATTCAAGACCATTTTCAAGCAGGTCTGGGATAATGCCCTGTAC
TGTGTGATGGGGCCCTACAGAATGAATACACTGATTCTGGCCGTGGTTTGGTTTGCCATG
GCATTCAGTTACTATGGACTGACAGTTTGGTTTCCTGATATGATCCGCTATTTTCAAGAT
GAAGAATACAAGTCTAAAATGAAGGTGTTTTTTGGTGAGCATGTGTACGGCGCCACAATC
AACTTCACGATGGAAAATCAGATCCACCAACATGGGAAACTTGTGAATGATAAGTTCACA
AGAATGTACTTTAAACATGTACTCTTTGAGGACACATTCTTTGACGAGTGCTATTTTGAA
GACGTAACATCAACAGATACCTACTTCAAAAATTGTACCATTGAATCAACCATCTTTTAC
AACACAGACCTCTACGAGCACAAGTTCATCAACTGTCGGTTTATCAACTCCACCTTCCTG
GAGCAGAAGGAGGGCTGCCACATGGACTTGGAGCAAGATAATGACTTCCTGATTTACCTC
GTCAGCTTCCTGGGCAGCCTGTCTGTCTTACCCGGGAACATCATTTCTGCCCTGCTCATG
GATAGAATTGGAAGGCTCAAGATGATTGGTGGCTCCATGCTAATCTCTGCAGTCTGCTGC
TTCTTCCTGTTTTTTGGCAACAGTGAGTCTGCAATGATCGGCTGGCAGTGCCTGTTCTGT
GGGACAAGCATTGCAGCCTGGAATGCTCTGGATGTGATCACAGTGGAGCTGTATCCCACC
AACCAGAGAGCAACAGCCTTCGGCATTCTCAATGGATTATGCAAATTTGGCGCCATCCTG
GGAAACACCATCTTTGCTTCTTTTGTTGGGATAACCAAAGTGGTCCCCATCCTTCTGGCT
GCTGCTTCTCTGGTTGGGGGTGGCCTGATTGCCCTTCGACTGCCAGAGACTCGAGAACAG
GTCCTGATGTGA
|
| Protein Properties |
| Number of Residues
| 683 |
| Molecular Weight
| 77443.7 |
| Theoretical pI
| 5.12 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["109-129", "149-169", "183-203", "206-226", "238-258", "278-298", "391-411", "536-556", "566-586", "593-613", "627-649", "654-672"]
|
| Protein Sequence
|
>Synaptic vesicle glycoprotein 2B
MDDYKYQDNYGGYAPSDGYYRGNESNPEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVK
AKQAKMAPSRMDSLRGQTDLMAERLEDEEQLAHQYETIMDECGHGRFQWILFFVLGLALM
ADGVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSM
SLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLG
IFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPES
PRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWY
QRWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQD
EEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDTFFDECYFE
DVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYL
VSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFC
GTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLA
AASLVGGGLIALRLPETREQVLM
|
| External Links |
| GenBank ID Protein
| 7662270 |
| UniProtKB/Swiss-Prot ID
| Q7L1I2 |
| UniProtKB/Swiss-Prot Entry Name
| SV2B_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_014848.4 |
| GeneCard ID
| SV2B |
| GenAtlas ID
| SV2B |
| HGNC ID
| HGNC:16874 |
| References |
| General References
| Not Available |