| Identification |
| HMDB Protein ID
| CDBP03226 |
| Secondary Accession Numbers
| Not Available |
| Name
| Translocon-associated protein subunit gamma |
| Description
| Not Available |
| Synonyms
|
- SSR-gamma
- Signal sequence receptor subunit gamma
- TRAP-gamma
|
| Gene Name
| SSR3 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in cotranslational protein targeting to membrane |
| Specific Function
| TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins |
| GO Classification
|
| Component |
| cell part |
| membrane part |
| translocon complex |
| sec61 translocon complex |
| macromolecular complex |
| intrinsic to membrane |
| protein complex |
| intrinsic to organelle membrane |
| intrinsic to endoplasmic reticulum membrane |
| integral to endoplasmic reticulum membrane |
| Process |
| protein targeting |
| protein targeting to membrane |
| cotranslational protein targeting to membrane |
| establishment of localization |
| transport |
| protein transport |
| intracellular protein transport |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q25.31 |
| SNPs
| SSR3 |
| Gene Sequence
|
>558 bp
ATGGCTCCTAAAGGCAGCTCCAAACAGCAGTCTGAGGAGGACCTGCTCCTGCAGGATTTC
AGCCGCAATCTCTCGGCCAAGTCCTCCGCGCTCTTCTTCGGAAACGCGTTCATCGTGTCT
GCCATCCCCATCTGGTTATACTGGCGAATATGGCATATGGATCTTATTCAGTCTGCTGTT
TTGTATAGTGTGATGACCCTAGTAAGCACATATTTGGTAGCCTTTGCATACAAGAATGTG
AAATTTGTTCTCAAGCACAAAGTAGCACAGAAGAGGGAGGATGCTGTTTCCAAAGAAGTG
ACTCGAAAACTTTCTGAAGCTGATAATAGAAAGATGTCTCGGAAGGAGAAAGATGAAAGA
ATCTTGTGGAAGAAGAATGAAGTTGCTGATTATGAAGCTACAACATTTTCCATCTTCTAT
AACAACACTCTGTTCCTGGTCGTGGTCATTGTTGCTTCCTTCTTCATATTGAAGAACTTC
AACCCCACAGTGAACTACATATTGTCCATAAGTGCTTCATCAGGACTCATCGCCCTCCTG
TCTACTGGCTCCAAATAG
|
| Protein Properties |
| Number of Residues
| 185 |
| Molecular Weight
| 21080.3 |
| Theoretical pI
| 10.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["28-48", "55-76", "136-157", "164-184"]
|
| Protein Sequence
|
>Translocon-associated protein subunit gamma
MAPKGSSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAV
LYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDER
ILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIALL
STGSK
|
| External Links |
| GenBank ID Protein
| 33150654 |
| UniProtKB/Swiss-Prot ID
| Q9UNL2 |
| UniProtKB/Swiss-Prot Entry Name
| SSRG_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF087907 |
| GeneCard ID
| SSR3 |
| GenAtlas ID
| SSR3 |
| HGNC ID
| HGNC:11325 |
| References |
| General References
| Not Available |