| Identification |
| HMDB Protein ID
| CDBP03224 |
| Secondary Accession Numbers
| Not Available |
| Name
| Translocon-associated protein subunit beta |
| Description
| Not Available |
| Synonyms
|
- SSR-beta
- Signal sequence receptor subunit beta
- TRAP-beta
|
| Gene Name
| SSR2 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in signal sequence binding |
| Specific Function
| TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins |
| GO Classification
|
| Component |
| intracellular membrane-bounded organelle |
| integral to membrane |
| cell part |
| membrane part |
| endoplasmic reticulum |
| intrinsic to membrane |
| organelle |
| membrane-bounded organelle |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21-q23 |
| SNPs
| SSR2 |
| Gene Sequence
|
>552 bp
ATGAGGCTGCTGTCATTTGTGGTGTTGGCTCTATTTGCTGTCACTCAAGCAGAGGAAGGA
GCCAGGCTTTTGGCTTCCAAATCACTGCTGAACAGATACGCCGTGGAGGGACGAGACCTG
ACCTTGCAGTACAACACCTACAATGTTGGCTCAAGTGCTGCATTAGACGTGGAACTATCT
GATGATTCCTTCCCTCCAGAAGACTTTGGCATTGTGTCTGGAATGCTCAATGTCAAATGG
GACCGGATTGCCCCTGCTAGCAATGTCTCCCACACTGTGGTCCTGCGCCCTCTCAAGGCT
GGTTATTTCAACTTCACCTCGGCAACAATTACTTACCTGGCCCAGGAGGATGGGCCCGTT
GTGATTGGCTCTACCAGTGCACCTGGACAGGGAGGAATCCTGGCTCAGCGGGAGTTTGAC
AGGCGATTCTCCCCTCATTTTCTGGACTGGGCAGCCTTTGGGGTCATGACCCTTCCCTCC
ATCGGCATCCCCCTGCTATTGTGGTACTCCAGCAAGAGGAAATATGACACTCCCAAAACG
AAGAAGAACTGA
|
| Protein Properties |
| Number of Residues
| 183 |
| Molecular Weight
| 20134.8 |
| Theoretical pI
| 8.79 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Translocon-associated protein subunit beta
MRLLSFVVLALFAVTQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELS
DDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPV
VIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKT
KKN
|
| External Links |
| GenBank ID Protein
| 62896759 |
| UniProtKB/Swiss-Prot ID
| P43308 |
| UniProtKB/Swiss-Prot Entry Name
| SSRB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK222600 |
| GeneCard ID
| SSR2 |
| GenAtlas ID
| SSR2 |
| HGNC ID
| HGNC:11324 |
| References |
| General References
| Not Available |